Eukaryotic DNA is organized differently than prokaryotes, containing multiple chromosomes made of linear DNA molecules packaged around histone proteins to form chromatin. The cell cycle regulates cell division, ensuring daughter cells receive a full copy of the genome through DNA replication and cell growth or repair. Researchers found inhibiting signaling pathways in brain cancer cells stopped their reproduction and migration, making them more sensitive to chemotherapy. Studying chromatin remodeling genes in pancreatic cancer showed restoring expression of missing genes slowed cancer cell growth and induced senescence.