Chromosomal abnormalities often involve gaining or losing chromosomes together across cancer types and can develop different cancers like kidney, bone, and liver cancers. Studies of consistent chromosomal aberrations in specific cancer types have identified some cancer-causing genes. Understanding chromosomal patterns may be key to preventing cancer development and progression.

2. FOLDING

3. FOLDING

4. • Many chromosomal pars
are lost or gained togeher
Patterns of across various cancer
chromosomes types.
• This chromosomal
Abnormality: aberrations can develop a
The key to differents cancer types
such as: Kidney, skeleton
cáncer? and liver cancer.
Making • The CPEB (Cytoplasmic
polyadenylation element
memories last: binding protein) is a
Prion-like RNA-binding protein that
promotes the elongation
protein plays of the polyadenine tail of
messenger RNA.CPEB
key role in most commonly activates
storing long- the target RNA for
translation, but can also
term memories. act as a repressor.

5. Making memories last: Prion-like protein plays
key role in storing long-term memories.
Science Daily (January. 23, 2012).

6. Making memories last: Prion-like protein plays
key role in storing long-term memories.
Science Daily (January. 23, 2012).
• The prion domain of CPEB causes self-
perpetuation in neurons and this is the
mechanism that maintains long-term memory
in neurons.

7. Making memories last: Prion-like protein plays
key role in storing long-term memories.
Science Daily (January. 23, 2012).
• The Orb2 and the CPEB has the same function
apparently , shows the organisms with relatively
simple nervous systems offer a realistic platform to
understand how and where memories are formed
and stored in defined neural circuits.

8. Making memories last: Prion-like protein plays
key role in storing long-term memories.
Science Daily (January. 23, 2012).

9. Making memories last: Prion-like protein plays
key role in storing long-term memories.
Science Daily (January. 23, 2012).
• This kind of study may help to the doctors and
the scientists to understand all pathologic process
in the neurodegerative disease, and also give
them an idea to treatment. In the new the
scientist tries to make emphasis in some common
pathology caused by proteins like: Alzheimer
Huntington Parkinson and Creutzfeldt-Jakob this
show us that oligomer-linked diseases are
relatively common.

10. Patterns of chromosome abnormality: The key
to cancer?
Science daily (Jan. 27, 2012)

11. Patterns of chromosome abnormality: The
key to cancer?
Science daily (Jan. 27, 2012)
• Cancer may be defined as a progressive series of
genetic events that occur in a single clone of cells
because of alterations in a limited number of specific
genes: the oncogenes and tumor suppressor genes.

12. Patterns of chromosome abnormality: The
key to cancer?
Science daily (Jan. 27, 2012)
• The association of consistent chromosome
aberrations with particular types of cancer has
led to the identification of some of these genes
and the elucidation of their mechanisms of
action.

13. Patterns of chromosome abnormality: The key
to cancer?
Science daily (Jan. 27, 2012)

14. Patterns of chromosome abnormality: The
key to cancer?
Science daily (Jan. 27, 2012)

15. • The study and the
different theories about
the memory
development are very
important in the
medicine, because the
existence of oligomers
and proteins for example
the CPEB allows to find
new answer and new
treatment in the
neurological disease like
the Alzheimer or
dementia.

16. • The existence of this kind of proteins like CPEB in the neurons can
help to the medical staff to understand strange pathologies as well
as prion disease, because this kind of disease involve spread in the
brain of toxic oligomers of various protein, so only with the
interruption of spread of this protein could be the solution for the
creutzfel-jakob disease.

18. • The different kind of
embryonic cancer types can
be develop owing to a: the
abnormality in the synthesis
of chromosomes and the
chromosomes aberration.
From the information that
gives us a karyogram we can
prevent the development and
expansion of the cancer, and
we can to know since the
intrauterine life the high risk
of suffer it.

19. BIBILIOGRAFIA
• Patterns of chromosomes Abnormality: The
key to cancer? (Online)
http://www.sciencedaily.com/releases/2012/0
1/120123115527.htm (January. 23, 2012)
• Making memories last: Prion-like protein plays
key role in storing long-term memories
(online)
http://www.sciencedaily.com/releases/2012/0
1/120127162409.htm (January. 27, 2012)