Plasters are solid or semisolid masses that adhere to the skin when applied. They are used to provide protection and support, create an occlusive and macerating environment, and bring medication into close contact with the skin surface. They consist of a protective liner, drug-containing layer, and backing layer. Plasters are used for local or regional drug delivery and some therapeutic transdermal systems are used for long-term systemic delivery. Examples include nitroglycerin and estrogen patches.

1. - Plasters are solid or semisolid masses adhere to
the skin when spread upon cotton felt line or
muslin as a backing material and they are mainly
used to,
A- Afford protection and mechanical support.
B- Furnish an occlusive and macerating action.
C- Bring medication into close contact with the
surface of the skin.

2. •Protective
liner
•Drug
containing
layer
•Backing layer

3. 



adhesive plasters
medicated plasters are used for local or
regional drug delivery
transdermal delivery (or therapeutic) systems
(TTS) are used for long-term systemic
delivery of therapeutic agents through the
skin.
Examples: Nitroderm TTS, Estraderm TTS,
Durogesic, etc.

4. 

Also called a sticking plaster
Is a small dressing used for injuries not
serious enough to require a fullsize bandage.

5. 



The adhesive bandage protects the cut from
friction, bacteria, damage, or dirt.
Thus, the healing process of the body is less
disturbed.
Sometimes they have antiseptic properties.
An additional function is to hold the two cut
ends of the skin together to make the healing
process faster.

6. 

An adhesive bandage is usually covered by
woven fabric, plastic, or latex rubber which
has an adhesive.
Adhesive bandages usually have an absorbent
pad, which is sometimes medicated with an
antiseptic solution.

7. 

Some bandages have a thin, porous-polymer
coating over the pad to keep it from sticking
to the wound.
The bandage is applied such that the pad
covers the wound, and the fabric or plastic
sticks to the surrounding skin to hold the
dressing in place and prevent dirt from
entering the wound.

9. 



Band-Aid
Curad
Elastoplast
Nexcare

10. 
Versatis medicated plasters
Versatis medicated plasters contain the
active ingredient lidocaine.
Main use
Active ingredient
Manufacturer
Nerve pain following
shingles
Lidocaine
Grunenthal

11. 





Use with caution in
Severely decreased liver function.
Severely decreased kidney function.
Severe heart problems.
People taking medicines to treat an irregular
heart beat, for example mexiletine.
People using other local anaesthetics.

14. Contents:
 TTS 5 Patches: The average amount of active
substance nitroglycerine releases per
application in 24 hrs is 5mg (Per hour
releases 0.2mg).
 TTS 10 Patches: The average amount of
active substance nitroglycerine releases per
application in 24 hours is 10mg (Per hour
releases 0.4mg).

15. 

Drug Classification: Glyceryl Trinitrate Patch
Trade Name Manufacturer(s):
Novartis

16. 
Estraderm TTS patches contain the active
ingredient estradiol ,which is a naturally
occuring form of the main female sex
hormone, oestrogen.
Main use
Active ingredient
Manufacturer
Symptoms of the
menopause
Estradiol
Novartis

18. Used for
 Hormone replacement therapy to relieve
symptoms of the menopause.
 Second-line option for
preventing osteoporosis in postmenopausal
women who are at high risk of fractures and
cannot take other medicines licensed for
preventing osteoporosis (Estraderm TTS 50
only).

19. Use with caution in
 Decreased kidney function.
 Heart failure.
 History of diabetes.
 History of gallstones.
 History of migraines or severe headaches.
 History of epilepsy.
 History of asthma.

20. Side effects
 Breakthrough bleeding and spotting.
 Breast pain, tenderness or enlargement.
 Headache/migraine.
 Redness or itching at patch application site.
 Leg cramps.
 Fatigue.
 Weight changes.
 Vaginal thrush.
 Depression.
 Anxiety.
 Dizziness.

21. 
Duragesic (fentanyl) is an opioid analgesic
that is used for patients with chronic pain
that is persistent, not managed by other
opioids or non-steroidal analgesics, and are
opioid-tolerant.

23. USES
DURAGESIC is a transdermal formulation of
fentanyl indicated for the management of
persistent, moderate to severe chronic
pain in opioid-tolerant patients 2 years of
age and older when a continuous.

24. SIDE-EFFECTS
 Nausea, vomiting,
 dry mouth, constipation,
 hypotension and hypertension,
 bradycardia, somnolence,
 confusion, hallucinations,
 euphoria, pruritus, sweating and
 urinary retention.

25. 


www.netdoctor.co.uk
www.pakmedinet.com
Remington: The Science and Practice of
Pharmacy 21st edition pages no
948,1029,2309.