Niosomes are non-ionic surfactant-based vesicles that can be used to deliver drugs. They are divided into small unilamellar vesicles, large unilamellar vesicles, and multi-lamellar vesicles based on their size and number of bilayers. Niosomes can be used for controlled drug release, to improve drug stability and bioavailability, and for targeted drug delivery to tissues like the liver, spleen, and tumors. They have applications in drug delivery via various routes of administration like oral, topical, and intravenous delivery.