Human physiology explains the biological and chemical factors responsible for life through the study of the structure and function of the human body. The human body is made up of cells that come together to form tissues, organs and body systems. These systems work interdependently to maintain homeostasis, or internal stability, which is essential for survival. The major body systems include the circulatory, respiratory, digestive, urinary, integumentary, nervous, endocrine, immune, skeletal, and reproductive systems.