This document provides an overview of a hematology course taught by Dr. Ahmed Elshebiny. The course covers various topics in clinical hematology including the blood and bone marrow, abnormal blood counts, anemia, and other hematological disorders and diseases. It discusses approaches to classifying anemias and examines various blood cell parameters and abnormalities that can be observed in a blood film. Common causes of abnormalities in red blood cells, white blood cells, platelets, reticulocytes and other values are outlined. References for further learning are also provided.

2. Hematology Course: an overview of Clinical Hematology Dr. Ahmed Elshebiny , MD Lecturer of Internal Medicine Faculty of Medicine, Menoufyia University Former Clinical Research Fellow, Joslin Diabetes Center, Harvard University

4. Structure and Function The blood and bone marrow

7. Blood is continuously renewed

8. The Bone Marrow is the blood Factory May be exposed to damage or failure

14. Fetal and neonatal hemoglobins

15. HB and MCV values with age & sex

18. Aplastic Anemia

19. Bone marrow aspiration and biopsy

20. Bone marrow aspiration

21. P.N.H

22. Hematology Course (2): Clinical Hematology Abnormal Blood count

40. Hematology Course (3): Clinical Hematology Anemia : a clinical approach!

41. Anemia is operationally defined as a reduction in one or more of the major RBC measurements: hemoglobin concentration, hematocrit, or RBC count Keep in mind these are all concentration measures … most accurately measured by obtaining a RBC mass via isotopic dilution methods. Definition:

43. Normal blood film

44. Morphological approach

46. Reticulocytes

48. Iron difficiency anemia Thalassemia

49. Thalassemia

50. Sickle cell anemia

51. Spherocytosis

52. Hemolytic anemia

54. Macrocytic anemia

55. B 12 and folate deficiency

57. THANK YOU