This document discusses the generation of frequency modulation (FM) using direct and indirect methods. The direct method uses a reactance modulator like a varactor diode or FET placed across an LC oscillator tank circuit to vary the capacitance or inductance in proportion to the modulating voltage. The indirect method generates FM through phase modulation using a crystal oscillator and phase modulator, then detecting the phase changes to create FM. Vector diagrams are also presented to illustrate phase modulation. Effects of frequency changing like multiplication and mixing on FM signals are explained.
Details: https://electronicsembeddedworld.blogspot.com/2018/06/performance-management-mcq.html
FM demodulation involves changing the frequency variations in a signal into amplitude variations at baseband, e.g. audio. There are several techniques and circuits that can be used each with its own advantages and disadvantages.
In any radio that is designed to receive frequency modulated signals there is some form of FM demodulator or detector. This circuit takes in frequency modulated RF signals and takes the modulation from the signal to output only the modulation that had been applied at the transmitter.
There are several types of FM detector / demodulator that can be used. Some types were more popular in the days when radios were made from discrete devices, but nowadays the PLL based detector and quadrature / coincidence detectors are the most widely used as they lend themselves to being incorporated into integrated circuits very easily...
Salient Features:
The magnitude response is nearly constant(equal to 1) at lower frequencies
There are no ripples in passband and stop band
The maximum gain occurs at Ω=0 and it is H(Ω)=1
The magnitude response is monotonically decreasing
As the order of the filter ‘N’ increases, the response of the filter is more close to the ideal response
Frequency-Shift Keying, also known as FSK is a type of digital frequency modulation. It is also often called as binary frequency shift keying or BFSK
Similar to analog FM, it is a constant-amplitude angle modulation.
This presentation will discuss the concepts behind FSK
Details: https://electronicsembeddedworld.blogspot.com/2018/06/performance-management-mcq.html
FM demodulation involves changing the frequency variations in a signal into amplitude variations at baseband, e.g. audio. There are several techniques and circuits that can be used each with its own advantages and disadvantages.
In any radio that is designed to receive frequency modulated signals there is some form of FM demodulator or detector. This circuit takes in frequency modulated RF signals and takes the modulation from the signal to output only the modulation that had been applied at the transmitter.
There are several types of FM detector / demodulator that can be used. Some types were more popular in the days when radios were made from discrete devices, but nowadays the PLL based detector and quadrature / coincidence detectors are the most widely used as they lend themselves to being incorporated into integrated circuits very easily...
Salient Features:
The magnitude response is nearly constant(equal to 1) at lower frequencies
There are no ripples in passband and stop band
The maximum gain occurs at Ω=0 and it is H(Ω)=1
The magnitude response is monotonically decreasing
As the order of the filter ‘N’ increases, the response of the filter is more close to the ideal response
Frequency-Shift Keying, also known as FSK is a type of digital frequency modulation. It is also often called as binary frequency shift keying or BFSK
Similar to analog FM, it is a constant-amplitude angle modulation.
This presentation will discuss the concepts behind FSK
Electrical current, voltage, resistance, capacitance, and inductance are a few of the basic elements of electronics and radio. Apart from current, voltage, resistance, capacitance, and inductance, there are many other interesting elements to electronic technology. ... Use Electronics Notes to learn electronics online.
Hardware Analysis of Resonant Frequency Converter Using Isolated Circuits And...IJERD Editor
-LLC resonant frequency converter is basically a combo of series as well as parallel resonant ckt. For
LCC resonant converter it is associated with a disadvantage that, though it has two resonant frequencies, the
lower resonant frequency is in ZCS region[5]. For this application, we are not able to design the converter
working at this resonant frequency. LLC resonant converter existed for a very long time but because of
unknown characteristic of this converter it was used as a series resonant converter with basically a passive
(resistive) load. . Here, it was designed to operate in switching frequency higher than resonant frequency of the
series resonant tank of Lr and Cr converter acts very similar to Series Resonant Converter. The benefit of LLC
resonant converter is narrow switching frequency range with light load[6] . Basically, the control ckt plays a
very imp. role and hence 555 Timer used here provides a perfect square wave as the control ckt provides no
slew rate which makes the square wave really strong and impenetrable. The dead band circuit provides the
exclusive dead band in micro seconds so as to avoid the simultaneous firing of two pairs of IGBT’s where one
pair switches off and the other on for a slightest period of time. Hence, the isolator ckt here is associated with
each and every ckt used because it acts as a driver and an isolation to each of the IGBT is provided with one
exclusive transformer supply[3]. The IGBT’s are fired using the appropriate signal using the previous boards
and hence at last a high frequency rectifier ckt with a filtering capacitor is used to get an exact dc
waveform .The basic goal of this particular analysis is to observe the wave forms and characteristics of
converters with differently positioned passive elements in the form of tank circuits.
Electronics and Communication Engineering is the Branch of Engineering. Electronics and Communication Engineering field requires an understanding of core areas including Engineering Graphics, Computer Programming,Electronics Devices and Circuits-I, Network Analysis, Signals and Systems, Communication Systems, Electromagnetics Engineering, Digital Signal Processing, Embedded Systems, Microprocessor and Computer Architecture. Ekeeda offers Online Mechanical Engineering Courses for all the Subjects as per the Syllabus. Visit : https://ekeeda.com/streamdetails/stream/Electronics-and-Communication-Engineering
three level diode clamp inverter. that converts any type of DC ( rectified, PV cell, battery etc.) to AC supply. we made by mosfet and ardiuno . in this ppt we present the Simulink model of a three-level inverter and the hardware presentation of the inverter.
Design and Simulation of Low Pass Filter for Single phase full bridge Inverte...IJERA Editor
Sinusoidal pulse width modulation SPWM technique is widely preferred to other modulation techniques as the
Inverter output frequency obtained is equal to the required fundamental frequency. SPWM with unipolar voltage
switching is used as it results in cancellation of harmonic component at the switching frequencyin the output
voltage, also the sidebands of the switching frequency harmonics disappear and in addition to this, other
dominant harmonic at twice the switching frequency gets eliminated. Hence, due to these advantages unipolar
voltage switching with SPWMis used for Inverter switching. In this paper, an in-depth analysis of unipolar
voltage switching technique with SPWM as applied to a single-phase full bridge Inverter is described and
designing of an efficient, active low pass filter LPF is discussed for an particular cut-off frequency,푓푐 and
damping factor zeta, 휁 and the filter is placed at the output side of a single-phase full bridge Inverter and
therefore eliminating the harmonic component from the Inverter output voltage resulting in a pure sinusoidal ac
voltage waveform.
Introduction
Band Pass Amplifiers
Series & Parallel Resonant Circuits & their Bandwidth
Analysis of Single Tuned Amplifiers
Analysis of Double Tuned Amplifiers
Primary & Secondary Tuned Amplifiers with BJT & FET
Merits and de-merits of Tuned Amplifiers
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
2. Basic requirements to produce FM
Variable output frequency with the
variation proportional to the
instantaneous amplitude of the
modulating voltage.
The amplitude of the carrier remains
constant during modulation.
3.
4.
5. HOW FM IS GENERATED?
If either the capacitance or
inductance of an LC oscillator tank is
varied, FM is generated.
Two methods:
1. Direct method
2. Indirect method
6. DIRECT METHOD
To provide variation, reactance
modulator or varactor diode is
placed across the tank , and the tank
is tuned so that the oscillating
frequency is equal to the desired
carrier frequency.
The C or L is changed accordance
with modulating voltage.
7.
8. FET Reactance
Modulator
3 terminal reactance that can be
connected across tank circuit.
The value of this reactance is
proportional to the
trasconductance of the device.
9. THEORY
To determine Z, a voltage ‘v’ is
applied to the terminals A-A
between which the impedance is
to be measured, and the
resulting current ‘I’ is calculated
10. Impedance to be a pure reactance two
requirements must be fulfilled.
1. Bias network current ‘ib’ must be
negligible compared to the drain
current.
2. Drain to gate impedance (Xc) must
be greater than the gate to source
impedance (R).
11. Ceq = gmRC
Ceq depends on device gm and can
be varied with bias voltage.
Capacitance can be adjusted by
varying the components R and C.
This expression has the correct
dimensions of capacitance.
Xc > R
12. If R is not << than Xc the Vg
will no longer be exactly 90° out
of phase with the ‘v’.
Thus the input impedance will
no longer be purely reactive.
13. The gate to drain impedance is, in
practice made five to ten times the
gate to source impedance.
Let Xc = nR (at the carrier frequency)
in the capacitive RC reactance FET.
15. In all arrangements drain current must be
much greater than bias network current.
Commonly used oscillators:
1. Hartley oscillator
2. Colpitts (Clapp Gouriet) an RC
capacitive transistor reactance
modulator operates on tank circit.
16. VARACTOR DIODE
Junction capacitance varies linearly
with the applied voltage when the
diode is reverse biased.
It is employed together with a
reactance modulator to provide
automatic frequency correction for an
FM transmitter.
17. This diode is back biased to provide
the junction capacitance(capacitance
associated with charge variation in the
depletion layer) effect.
This bias is varied by the modulating
voltage which is in series with it.
It is often used for automatic
frequency control and remote tuning.
19. INDIRECT METHOD
Generating FM through phase
modulation , where a crystal oscillator
can be used.
Operating frequency for crystal
oscillator and phase modulator is
1MHz.
Armstrong system
20. Crystal oscillator: It is an electronic oscillator
circuit that uses the mechanical resonance of
a vibrating crystal of piezoelectric material
to create an electrical signal with a precise
frequency.
Phase modulation: It encodes a message
signal as variations in the instantaneous
phase of a carrier wave.
21.
22.
23. BLOCK DIAGRAM EXPLANATION
The effect of mixing on an FM
signal is to change the center
frequency only.
The effect of frequency
multiplication is to multiply center
frequency and deviation equally.
24. Frequency mixer: A nonlinear
electrical circuit that creates new
frequencies from two signals applied
to it.
Frequency multiplier: An electronic
circuit that generates an output
signal whose output frequency is a
harmonic of its input frequency.
26. DIAGRAM 1
The resultant of two sideband
frequency vectors is always in phase
with the unmodulated carrier vector.
So there is a phase change of 90° of
sideband voltages with carrier vector.
27. DIAGRAM 2
If an amplitude modulated
voltage is added to an
unmodulated voltage of the
same frequency and the two
are kept 90° apart in phase.
28. DIAGRAM 3
The carrier of the amplitude modulated
signal has been removed so that only the two
sidebands are added to unmodulated
voltage.
The resultant of the 2 sideband voltages will
always be in quadrature with the carrier
voltage.
Modulation↑ phase deviation ↑ hence phase
modulation is obtained
29. The resultant voltage will be phase
modulated but with little amplitude
modulation also.
If amplitude limiter is used then there will be
phase modulation only.
The modulating voltage will have to be
equalized before it enters the balanced
modulator.
30. The modulating voltage will have to
be equalized before it enters the
balanced modulator.
In FM broadcasting,ῳL =R at 30Hz.
As frequency increases above that
the output of the equalizer will fall at
a rate of 6dB/octave.
31.
32. Effects of frequency changing on
an FM signal
Armstrong system is often used with
reactance modulator.
Modulation index is multiplied by
the same factor as the center
frequency.
33. If a frequency modulated signal fc is
fed to a frequency doubler, the output
signal will contain twice each input
frequency. (2fc±2 )
When a frequency modulated wave is
mixed with frequency f0 then output will
be fc-f0- and fc-f0+ .
Maximum frequency is a .
34. Modulating frequency has remained
constant in both cases.
But the modulating index will be
affected.
It is possible to raise the modulation
index without affecting the center
frequency by multiplying both by 9 and
mixing the result with a frequency 8
times the original frequency.
35. Characteristics of Phase
modulation
Angle of phase modulation is
proportional to the amplitude of the
modulating voltage not the angle.
To keep the angle of deviation small
both mixing and multiplication must
be done.
36. For broadcast purpose,
operating frequency is 180MHz
with initial fc=1MHz and
=60Hz.
Hence a deviation 10.8kHz at
180MHz is achieved and that is
adequate for FM mobile
network.
