English scientist Robert Hooke first observed cells in cork over 300 years ago under a microscope. Scientists later established that all living things are composed of cells, the smallest unit of life, and that new cells arise only from pre-existing cells, according to the cell theory. Cells contain water and four basic macromolecules - nucleic acids which carry genetic information, proteins which perform most cell functions, lipids which form cell membranes and store energy, and carbohydrates which store energy and provide structure.