Hyphenated technique is a combination or coupling of two analytical techniques with the help of proper interface.
In this presentation Hyphenated techniques-LC-MS/MS, GC-MS/MS, HPTLC-MS has been discussed
Hyphenated technique is a combination or coupling of two analytical techniques with the help of proper interface.
In this presentation Hyphenated techniques-LC-MS/MS, GC-MS/MS, HPTLC-MS has been discussed
The versatile instrument is used to isolate unknown compounds from a HPTLC/TLC plate and transfer them into a mass spectrometer for identification or structure elucidation.
Process of implementing and developing technical standards based on the consensus of different parties that include firms, users, interest groups, standards organizations and governments
Introduction
Definition
History
Types of chromatography
Principle of column chromatography
Types of column chromatography
Process of column chromatography
Requirement
Procedure
Precautions
Applications
Advantage of Column chromatography
Disadvantage of Column chromatography
Conclusion
References
Industrial Applications Of Chromatography Techniquerita martin
Chromatography Technologies plays vital role in various industrial application sectors, this techniques as been used across various chemical and pharmaceutical industries. This technique is used to purify sugar from molasses, separation of enantiomers and purification of pharmaceutical proteins, pharmaceutical industry for the purification of enantiomers from racemic mixtures. Its applications were also used in food chemistry, biochemistry, petro chemistry, pharmaceutical chemistry. Also plays important roles in Purification of proteins, pharmaceuticals, fine chemicals
The versatile instrument is used to isolate unknown compounds from a HPTLC/TLC plate and transfer them into a mass spectrometer for identification or structure elucidation.
Process of implementing and developing technical standards based on the consensus of different parties that include firms, users, interest groups, standards organizations and governments
Introduction
Definition
History
Types of chromatography
Principle of column chromatography
Types of column chromatography
Process of column chromatography
Requirement
Procedure
Precautions
Applications
Advantage of Column chromatography
Disadvantage of Column chromatography
Conclusion
References
Industrial Applications Of Chromatography Techniquerita martin
Chromatography Technologies plays vital role in various industrial application sectors, this techniques as been used across various chemical and pharmaceutical industries. This technique is used to purify sugar from molasses, separation of enantiomers and purification of pharmaceutical proteins, pharmaceutical industry for the purification of enantiomers from racemic mixtures. Its applications were also used in food chemistry, biochemistry, petro chemistry, pharmaceutical chemistry. Also plays important roles in Purification of proteins, pharmaceuticals, fine chemicals
Aula de Apresentação do Seminário: "SOBRE A IGREJA..."
Ministrado durante a E.B.D. da Igreja Batista Central de Jacarepaguá, pelo Pr. Júlio César.
Mais informações no Site: http://www.ibcjrj.com.br
Chromatography is a technique for separating various inorganic and organic compounds. It is one of the separation techniques used as differential migration. It is more advantageous over conventional separating methods such as crystallization, solvent extraction and distillation. The purpose of presentation is to present various chromatographic techniques included a few advanced forms such as FC, HPLC,UPLC and UPCC (Super Critical chromatography).These are rapid forms of chromatographic techniques based on air pressure driven, optimized for rapid and precise separation of an organic compound.
Hyphenated techniques have received ever-increasing attention as the principal means to solve complex analytical problems.
Hyphenated techniques are widely used in chemistry and biochemistry and used for both quantitative and qualitative analysis of unknown compounds in complex natural product extracts or fraction and estimation of protein samples also.
The hyphenated technique is a combination or coupling of two analytical techniques with the help of a proper interface.
The aim of the coupling is to obtain an information-rich detection for both identification and quantification compared to that with a single analytical technique.
SEPARATION, BIOANALYTICAL TECHNIQUES, EXTRACTION, LC MS, LIQUID CHROMATOGRAPHY AND MASS SPECTROSCOPY, MBAT, M.PHARM, PHARMACEUTICAL ANALYSIS, 1 ST YEAR
A Review on Step-by-Step Analytical Method Validationiosrphr_editor
When analytical method is utilized to generate results about the characteristics of drug related samples it is essential that the results are trustworthy. They may be utilized as the basis for decisions relating to administering the drug to patients. Analytical method validation required during drug development and manufacturing and these analytical methods are fit for their intended purpose. To comply with the requirements of GMP pharmaceutical industries should have an overall validation policy which documents how validation will be performed. The purpose of this validation is to show that processes involved in the development and manufacture of drug, production and analytical testing can be performed in an effective and reproducible manner. This review article provides guidance on how to perform validation characteristics for the analytical method which are utilized in pharmaceutical analysis.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
Safalta Digital marketing institute in Noida, provide complete applications that encompass a huge range of virtual advertising and marketing additives, which includes search engine optimization, virtual communication advertising, pay-per-click on marketing, content material advertising, internet analytics, and greater. These university courses are designed for students who possess a comprehensive understanding of virtual marketing strategies and attributes.Safalta Digital Marketing Institute in Noida is a first choice for young individuals or students who are looking to start their careers in the field of digital advertising. The institute gives specialized courses designed and certification.
for beginners, providing thorough training in areas such as SEO, digital communication marketing, and PPC training in Noida. After finishing the program, students receive the certifications recognised by top different universitie, setting a strong foundation for a successful career in digital marketing.
Biological screening of herbal drugs: Introduction and Need for
Phyto-Pharmacological Screening, New Strategies for evaluating
Natural Products, In vitro evaluation techniques for Antioxidants, Antimicrobial and Anticancer drugs. In vivo evaluation techniques
for Anti-inflammatory, Antiulcer, Anticancer, Wound healing, Antidiabetic, Hepatoprotective, Cardio protective, Diuretics and
Antifertility, Toxicity studies as per OECD guidelines
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
5. LC-MS
Liquid chromatography–mass spectrometry
1) Most frequently used technique in the field of bioanalysis.
2) Components of a complex mixture must be detected and identified.
3) LC-MS is frequently used in drug development at many different
stages including
- peptide mapping,
- glycoprotein mapping,
- natural products de-replication,
- in vivo drug screening,
- impurity identification,
-quantitative bio-analysis and quality control
6. HPTLC
High performance thin layer chromatography
1) Used in analyzing the purity and efficacy of many
pharmaceutical preparations and dosage forms.
2) It is also an ideal screening tool for adulterations.
3) HPTLC is used for purity control of chemicals,
pesticides, steroids, and water analysis.
4) Phytochemical analysis, biomedical analysis, herbal
drug quantification.
7. GAS CHROMATOGRAPHY
1) Qualitative analysis :
a) By comparing the retention times/volumes of the
unknown with the standard.
b) By comparing the individual components.
2) Quantitative analysis :
- depends upon the fact that the area unde a single
component peak is proportional to quantity of the detected
component.
8. 3) Miscellaneous :
a) Detection of steroids
b) Analysis of foods
c) Separation & identification of lipids, proteins,
carbohydrates, vitamins, pesticides .
d) Analysis of dairy products
e) Separation & identification of volatile materials like
plastics, natural & synthetic polymers.
9. GC-MS
Gas chromatography–mass spectrometry
1) Sports anti-doping analysis
-GC-MS is the main tool used in sports anti-doping laboratories
to test athletes' urine samples for prohibited performance-
enhancing drugs.
e.g. anabolic steroids
2) Food, beverage and perfume analysis.
3) Law enforcement
-GC-MS is increasingly used for detection of illegal narcotics.
10. 4) Separation & identification of degradation products of
organic & organometallics making the elucidation of their
stuctures.
5) Diagnosis of inborn errors of metabolism in New borns.
11. Supercritical Fluid
Chromatography
SFC is used in industry primarily for separation of chiral
molecules,
SFC is now commonly used for achiral separations and
purifications in the pharmaceutical industry.
12. UPLC
Ultra Performance Liquid Chromatography
1. LOW SAMPLE CONSUMPTION
2. TIME SAVING
3. DRUG DISCOVERY
4. ANALYSIS OF ENVIRONMENTAL RESIDUES
5. SEPARTION OF AMINO ACID