Mathematical Modeling for Practical ProblemsLiwei Ren任力偉
Mathematical modeling is an important step for developing many advanced technologies in various domains such as network security, data mining and etc… This lecture introduces a process that the speaker summarizes from his past practice of mathematical modeling and algorithmic solutions in IT industry, as an applied mathematician, algorithm specialist or software engineer , and even as an entrepreneur. A practical problem from DLP system will be used as an example for creating math models and providing algorithmic solutions.
Mathematical Modeling for Practical ProblemsLiwei Ren任力偉
Mathematical modeling is an important step for developing many advanced technologies in various domains such as network security, data mining and etc… This lecture introduces a process that the speaker summarizes from his past practice of mathematical modeling and algorithmic solutions in IT industry, as an applied mathematician, algorithm specialist or software engineer , and even as an entrepreneur. A practical problem from DLP system will be used as an example for creating math models and providing algorithmic solutions.
Differential geometry three dimensional spaceSolo Hermelin
This presentation describes the mathematics of curves and surfaces in a 3 dimensional (Euclidean) space.
The presentation is at an Undergraduate in Science (Math, Physics, Engineering) level.
Plee send comments and suggestions to improvements to solo.hermelin@gmail.com. Thanks/
More presentations can be found at my website http://www.solohermelin.com.
Classification of mathematical modeling,
Classification based on Variation of Independent Variables,
Static Model,
Dynamic Model,
Rigid or Deterministic Models,
Stochastic or Probabilistic Models,
Comparison Between Rigid and Stochastic Models
Properties of Caputo Operator and Its Applications to Linear Fractional Diffe...IJERA Editor
The purpose of this paper is to demonstrate the power of two mostly used definitions for fractional differentiation, namely, the Riemann-Liouville and Caputo fractional operator to solve some linear fractional-order differential equations. The emphasis is given to the most popular Caputo fractional operator which is more suitable for the study of differential equations of fractional order..Illustrative examples are included to demonstrate the procedure of solution of couple of fractional differential equations having Caputo operator using Laplace transformation. Itshows that the Laplace transforms is a powerful and efficient technique for obtaining analytic solution of linear fractional differential equations
* Model exponential growth and decay.
* Use Newton’s Law of Cooling.
* Use logistic-growth models.
* Choose an appropriate model for data.
* Express an exponential model in base e.
Differential geometry three dimensional spaceSolo Hermelin
This presentation describes the mathematics of curves and surfaces in a 3 dimensional (Euclidean) space.
The presentation is at an Undergraduate in Science (Math, Physics, Engineering) level.
Plee send comments and suggestions to improvements to solo.hermelin@gmail.com. Thanks/
More presentations can be found at my website http://www.solohermelin.com.
Classification of mathematical modeling,
Classification based on Variation of Independent Variables,
Static Model,
Dynamic Model,
Rigid or Deterministic Models,
Stochastic or Probabilistic Models,
Comparison Between Rigid and Stochastic Models
Properties of Caputo Operator and Its Applications to Linear Fractional Diffe...IJERA Editor
The purpose of this paper is to demonstrate the power of two mostly used definitions for fractional differentiation, namely, the Riemann-Liouville and Caputo fractional operator to solve some linear fractional-order differential equations. The emphasis is given to the most popular Caputo fractional operator which is more suitable for the study of differential equations of fractional order..Illustrative examples are included to demonstrate the procedure of solution of couple of fractional differential equations having Caputo operator using Laplace transformation. Itshows that the Laplace transforms is a powerful and efficient technique for obtaining analytic solution of linear fractional differential equations
* Model exponential growth and decay.
* Use Newton’s Law of Cooling.
* Use logistic-growth models.
* Choose an appropriate model for data.
* Express an exponential model in base e.
NCV 4 Mathematical Literacy Hands-On Support Slide Show - Module 1 Part 2Future Managers
This slide show complements the learner guide NCV 4 Mathematical Literacy Hands-On Training by San Viljoen, published by Future Managers Pty Ltd. For more information visit our website www.futuremanagers.net
Physical Quantities--Units and Measurement--Conversion of UnitsKhanSaif2
This presentation covers physical quantities and their types, units and their types, conversion of units and order of magnitude in a very interactive manner. I hope this presentation will be helpful for teachers as well as students.
Pada Transformasi Laplace bag. kedua, sifat-sifat transformasi laplace yang lebih mendalam dan khusus akan dipelajari. Sifat-sifat ini akan banyak digunakan dalam penerapan metode transformasi laplade dalam menyelesaikan masalah nilai awal dengan persamaan diferensial yang yang berkaitan dengan fungsi-fungsi tangga (piecewise function)
Transformasi Laplace adalah transformasi yang sering digunakan untuk menyelesaikan masalah syarat awal. Metode penyelesaian persamaan diferensial biasa menggunakan transformasi laplace terbukti cukup ampuh digunakan untuk menyelesaikan berbagai masalah nilai awal.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
2. Melalui pengamatan dan proses berpikir (reasoning), kita mampu
menjelaskan apa yang terjadi di alam secara sederhana
Ahli pikir Yunani yang pertama kali menemukan bahwa
matematika tidak hanya dapat digunakan untuk menghitung,
namun juga untuk mempelajari alam semesta.
Penemu Pertama sistem berpikir logis (logical reasoning) yang
merupakan akar dari pemodelan
Salah satu dari The Seven Sages of Greece
Beberapa hasil pemikiran:
1. Memprediksi gerhana matahari pada 25 Mei 585 SM dengan
tepat (dari The Historis of Herodotus).
2. Menggunakan geometri untuk menghitung tinggi piramida
dan jarak kapal dari pelabuhan.
PHYTAGORAS
THALES of MILETUS
(624-546 SM)
3. • Model matematika adalah jembatan antara dunia nyata (real world) dengan dunia
berpikir (thinking) untuk memecahkan suatu masalah.
• Pemodelan (Modelling) adalah proses menerima, memfomulasikan, memproses,
dan menampilkan kembali persepsi dunia nyata.
• Pemodelan dapat menghindari atau mengurangi biaya yang dibutuhkan, biaya yang
tidak perlu ataupun eksperimen yang tidak mungkin dilakukan di dunia nyata.
Neglected variables
Exogenous variables Endogenous variables
4. 1. Simplify reality
2. Created for a particular purposes
3. Attempt to mimic nature
4. Able to consider only certain effects, the object being to see which effects
account for given observations and which effect are immaterial.
5. Never ends process, since the mathematical model is continually revised
and improved
Modelling is essential to “explain” the world.
5. REAL-WORLD PROBLEM Well-defined
math problem
Solution to
model behavior
Predictions/
Explanations
simplification
inform
interpretation
observation
Governing
equations
DATA
MATH WORLD‘REAL’ WORLD
Make assumptions,
Start simple
Solve with whatever it
takes
(analytic/asymptotic/
numerical)
validate
6. PROPERTIES OF THE MODEL
FIDELITY
The preciseness of a
model’s representation of
reality
Real-world observations
Experiments
Simulations
Constructed Models
Selected Models
Real-world observations
Experiments
Simulations
Constructed Models
Selected Models
Real-world
observations
Experiments
Simulations
Constructed Models
Selected Models
COSTS
The total cost of the
modeling process
FLEXIBILITY
The ability to change and control
conditions affecting the model as
required data are gathered
7. Model Dinamik Stokastik
Model yang dihasilkan dari interaksi
antara skala waktu dan ketidakpastian
Tanpa mengandalkan data riil
Dari pengamatan empiris data riil
Empiris
Analitis
DATA RIIL
tidak mempertimbangkan aspek waktu
mempertimbangkan aspek waktu
Dinamik
Statis
SKALA WAKTU
tidak mempertimbangkan aspek ketidakpastian
mempertimbangkan aspek ketidakpastian
Stokastik
Determinisitik
KETIDAKPASTIAN
Replication of
behavior
Mathematical
Representation
Phenomenon
of interest
Model construction
Model Selection
Experimentation
Simulation
8. 1. A spring-mass system
2. Modeling change
a. A saving certificate
b. Sewage Treatment
c. Mortaging Home
d. Growth of a Yeast Culture
e. Growth of a Yeast Culture Revisited
f. Spread of a contagious disease
g. Decay of Digoxin in the bloodstream
h. Heating of a cooled object
3. Systems of difference equations
a. A car Rental company
b. The Battle of Trafalgar
c. Traveler’s Tendencies at a Regional Airport
9. Consider a spring-mass system, such as the one shown in figure below. We conduct an
experiment to measure the stretch of the spring as a function of the mass (measured
as weight) placed on the spring. Consider the data collected for this experiment,
displayed in Table.
Mass ∆𝒙
50 1.000
100 1.875
150 2.750
200 3.250
250 4.375
300 4.875
350 5.675
400 6.500
450 7.250
500 8.000
550 8.750
𝑆𝑙𝑜𝑝𝑒 =
4.875 − 3.25
300 − 200
= 0.01625
∆𝒙 = 𝟎. 𝟎𝟏𝟔𝟐𝟓 𝒎
10. Change = Future Value – Present value
Future Value = Present Value + Change
𝑎 𝑛+1 = 𝑎 𝑛 + ∆𝑎 𝑛
If the behavior is taking place over iscrete time period, the preceding construct
lead to a difference equations.
If the behavior is taking place continuously with respect to time, then the
conctruct leads to a differential equation
11. Consider the value of a savings certificate initially worth $1000 that accumulates interest
paid each month at 1% per month. No deposits or withdrawal occured in the account. The
following sequences of number represents the value of the certificate month by month.
𝐴 = (1000,1010,1020.10,1030.30, … )
𝒂 𝒏+𝟏 = 𝟏. 𝟎𝟏𝒂 𝒏, 𝒏 = 𝟎, 𝟏, 𝟐, …
𝒂 𝟎 = 𝟏𝟎𝟎𝟎
12. Six years ago, your parents purchased a home by financing $80.000 for 20 years,
paying monthly payments of $880.87 with a monthly interest of 1%. They have
made 72 payments and wish to know how much they owe on the mortgage,
which they are considering paying off with an inheritance they received.
Answer :
The change in the amount owed each period increases by the amount of interest
and decreases by the amount of the payment :
∆𝑏 𝑛 = 𝑏 𝑛+1 − 𝑏 𝑛 = 0.01𝑏 𝑛 − 880.87
with initial condition 𝑏0 = 80000.
13. The data in table below were collected from an experiment measuring the growth of a
yeast culture. The graph represents the assumption that the change in population is
proportional to the current size of the population. That is,
∆𝑝 𝑛 = 𝑝 𝑛+1 − 𝑝 𝑛 = 𝑘𝑝 𝑛,
where 𝑝 𝑛 represents the size of the population biomass after 𝑛 hours, and 𝑘 is a
positive constant. The value of 𝑘 depends on the time measurement.
Time in
hours
(n)
Observed yeast
Biomass
(pn)
Change in
Biomass
(pn+1-pn)
0 9.6
1 18.3 8.7
2 29.0 10.7
3 47.2 18.2
4 71.1 23.9
5 119.1 48.0
6 174.6 55.5
7 257.3 82.7
14. From the third column of the data, note that the change in population per hour
becomes smaller as the resources become more limited or constrained. From the
graph of population versus time, the population appears to be approaching a limiting
value, or carrying capacity. Based on our graph, we estimate the carrying capacity to
be 665. Nevertheless, as 𝑝 𝑛 approaches 665, the change dose slow considerably.
Because 665 − 𝑝 𝑛 gets smaller as 𝑝 𝑛 approaches 665, we propose the model
∆𝑝 𝑛 = 𝑝 𝑛+1 − 𝑝 𝑛 = 𝑘 665 − 𝑝 𝑛 𝑝 𝑛
Time in
biomass
n
Yeast
Biomass
pn
Change
per hour
pn+1-pn
0 9.6 8.7
1 18.3 10.7
2 29.0 18.2
3 47.2 23.9
4 71.1 48.0
5 119.1 55.5
6 174.6 82.7
pn+1-pn pn(665-pn)
8.7 6291.84
10.7 11834.61
18.2 18444.00
23.9 29160.16
48.0 42226.29
55.5 65016.69
82.7 85623.84
15. Suppose that there are 400 students in a college dormitory and that one or more
students has a severe of the flu. Let 𝑖 𝑛 represent the number of infected students after
𝑛 time periods, Assume that some interaction between those infecte and those not
infected is required to pass on the disease. If all are susceptible to the disease, then
400 − 𝑖 𝑛 represents those susceptible but not yet infected. If those infected remain
contagious, we can model the change of those infected as a proportionality to the
product of those infected by those susceptible but not yet infected, or
∆𝑖 𝑛 = 𝑖 𝑛+1 − 𝑖 𝑛 = 𝑘𝑖 𝑛 400 − 𝑖 𝑛
16. Digoxin is used in the treatment of heart disease. Doctors must prescribe an amount
of medicine that keeps the concentration of digoxin in the bloodstream above an
effective level without exceeding a safe level (there is a variation among patients).
For an initial dosage of 0.5 mg in the bloodstream, Table below shows the amount of
digoxin 𝑎 𝑛 remaining in the blood stream of particular patient after 𝑛 days, together
with the change ∆𝑎 𝑛 each days.
n 0 1 2 3 4 5 6 7 8
𝑎 𝑛 0.5 0.345 0.238 0.164 0.113 0.078 0.054 0.037 0.026
∆𝑎 𝑛 -0.155 -0.107 -0.074 -0.051 -0.035 -0.024 -0.016 -0.011
𝑎 𝑛+1 = 0.69𝑎 𝑛, 𝑎0 = 0.5
17. Suppose a cold can of soda is take from a refrigerator and placed in a warm classroom and
we measure the temperature periodically. The temperature of the soda is initially 400 F
and the room temperature is 720F. Temperature is a measure of energy per unit volume.
Because the volume of the soda is small relative to the volume of the room, we would
expect the room temperature to remain constant. Furthermore, we assume the entire can
of soda is the same temperature, neglecting variation within the can. We might expect the
change in temperature per time period to be greater when the difference in temperature
between the soda and the room is large and the change in temperature per unit time to
be less when the differences in temperatire is small.
Answer:
Letting 𝑡 𝑛 represent the temperature of the soda after 𝑛 time periods, and letting 𝑘 be a
positive constant of proportionality we propose
∆𝑡 𝑛 = 𝑡 𝑛+1 − 𝑡 𝑛 = 𝑘 72 − 𝑡 𝑛 , 𝑡0 = 40
18. A sewage treatment plant processes raw sewage to produce usable fertilizer and clean
water by removing all other contaminants. The process is such that each hour 12% of
remaining contaminants in a processing tank are removed. What percentage of the sewage
would remain after 1 day? How long would it take to lower the amount of sewage by half?
How long until the level of sewage is down to 10% of the original level?
Answer :
Let the initial amount of sewage contaminants be 𝑎0 and let 𝑎 𝑛 denote the amount after 𝑛
hours. We then build the model as
𝑎 𝑛+1 = 𝑎 𝑛 − 0.12𝑎 𝑛 = 0.88𝑎 𝑛
Solusi : 𝑎 𝑘 = 0.88 𝑘
𝑎0
a. n = 1 days = 24 hours => 𝑎24 = 0.88 24
𝑎0 ≈ 45% 𝑎0
b. 𝑎 𝑛 = 50% 𝑎0 => 𝑛 = 5.4223 hours
c. 𝑎 𝑛 = 10% 𝑎0 => 𝑛 = 18.01 hours
19. A car rental company has distributorships is Orlando and Tampa. The company
specializes in catering to travel agents who want to arrange tourist activities in both cities.
Consequently, a traveler will rent a car in one city and drop the car off in the second city.
Travelers may begin their itinerary in either city. The company wants to determine how
much to charge for this drop-off convenience. Because cars are dropped off in both cities,
will a sufficient number of cars ends up in each city to satisfy the demand for cars in that
city? If not, how many cars must the company transport from Orlando to Tampa or from
Tampa to Orlando? The answers these questions will help the company figure out its
expected costs.
The historical records reveal that 60% of the cars rented in Orlando are returne to Orlando,
whereas 40% ended up in Tampa. Of the cars rented from Tampa office, 70% are returned to
Tampa, whereas 30% end up in Orlando.
Answer :
Let 𝑛 represent the number of business days. Define
𝑂 𝑛= the number of cars in Orlando at the end of day 𝑛
𝑇𝑛= the number of cars in Tampa at the end of day 𝑛
Thus the historical records reveal the system
𝑂 𝑛+1 = 0.6𝑂𝑛 + 0.3𝑇𝑛
𝑇𝑛+1 = 0.4𝑂 𝑛 + 0.7𝑇𝑛
20. In the battle of Trafalgar in 1805, a combined French and Spanish naval force under
Napoleon fought a British naval force under Admiral Nelson. Initially, the Frech-Spanish force
had 33 ships and British had 27 ships. During an encounter, each side suffers a loss equal to
10% of the number of ships of the opposing force. For full-force engagements, who will be
the winner of this battle ? (Fractional value are meaningful and indicate that one or more
ships are not at full capacity.)
Answer :
Let 𝑛 denote the encounter stage during the course of the battle and define
𝐵 𝑛 = the number of British ships at stage 𝑛
𝐹𝑛 = the number of French-Spanish ships at stage 𝑛
Then, after an encounter at stage 𝑛, the number of ships remaining on each side is
𝐵 𝑛+1 = 𝐵 𝑛 − 0.1𝐹𝑛, 𝐵0 = 27
𝐹𝑛+1 = 𝐹𝑛 − 0.1𝐵𝑛, 𝐹0 = 33
21. 3th day2nd day1st day
Napoleon’s force of 33 ships was arranged essentially along a line separated into three groups as
shown in figure below.
Lord Nelson’s strategy was to engage force A with 13 British ships (holding 14 in reserve). He
then planned to combine those ships that survived the skirmish against force A with the 14 ships
in reserve to engage force B. Finally, after the battle with force B, he planned to use all
remaining ships to engage force C. Assuming each side loses 15% of the number of ships of the
opposing force for each of the three battle. Who is the winner of this battle?
Force C =13Force B = 17Force A = 3
Force A = 13 Force B = 14
Force C =
remaining ships
22. Consider a regional airport that is supported by three major airlines, American
airlines, united airlines, and US airways, each flying out to respective hubs. We
survey the weekly local business travelers and find 75% of those who traveled on US
Airways traveled again on US Airways, 5% switched to fly United and 20%
switched to fly American. Of those who traveled of United, 60% traveled again on
United but 20% switched to US Airways and 20% switched to American. Of those
who traveled on American, only 40% remained with American, 40% switched to US
Airways and 20% switched to United. We assume these tendencies continue week to
week an that no additional local business travelers enter or leave the system. If the
system has 4000 weekly travelers, how are the long-term behaviour of traveler
number?
Answer :
Let 𝑛 represent the 𝑛th week of traveling and define
𝑆 𝑛= the number of US Airways travelers in week 𝑛
𝑈 𝑛= the number of United Airlines travelers in week 𝑛
𝐴 𝑛= the number of American Airlines travelers in week 𝑛
We have the following dynamical system as
𝑆 𝑛+1 = 0.75𝑆 𝑛 + 0.20𝑈 𝑛 + 0.40𝐴 𝑛
𝑈 𝑛+1 = 0.05𝑆 𝑛 + 0.60𝑈 𝑛 + 0.20𝐴 𝑛
𝐴 𝑛+1 = 0.20𝑆 𝑛 + 0.20𝑈 𝑛 + 0.40𝐴 𝑛
23. Suppose a species of spotted owls competes for survival in a habitat that also supports
hawks. Suppose also that in the absence of the other species, each individual species
exhibits unconstrained growth in which the change in the population during an interval of
time (such as 1 days) is proportional to the population size at the beginning of the interval.
The effect of the presence of the second species is to diminish the growth rate of the other
species, and vice versa. We will assume that this decrease is appriximately proportional to
the number of possible interactions between two species (although there are many ways to
model the mutually detrimental interaction of the two species). If 𝑂 𝑛 represents the size of
the spotted owl population at the end of day 𝑛 and 𝐻 𝑛 represents the competing hawk
population, then contruct mathematical model of Owl and hawk population !
Answer :
𝑂 𝑛=represents the size of the spotted owl population at the end of day 𝑛
𝐻 𝑛=represents the competing hawk population
∆𝑂 𝑛 = 𝑘1 𝑂𝑛 − 𝑘3 𝑂 𝑛 𝐻 𝑛
∆𝐻 𝑛 = 𝑘2 𝐻 𝑛 − 𝑘4 𝑂 𝑛 𝐻 𝑛
With
𝑘1 and 𝑘2 are the constant positive growth rates.
𝑘3 and 𝑘4 are the constant positive competition rates
.
Do the simulation with 𝑘1 = 0.2, 𝑘2 = 0.3, 𝑘3 = 0.001, 𝑘4 = 0.002 and variate
the Initial condition
𝑂 𝑛+1 = 1 + 𝑘1 𝑂𝑛 − 𝑘3 𝑂𝑛 𝐻 𝑛
𝐻 𝑛+1 = 1 + 𝑘2 𝐻 𝑛 − 𝑘4 𝑂𝑛 𝐻 𝑛