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TRANSPORT OF SMALL MOLECULE ACROSS CELL
MEMBRANE: PASSIVE MECHANISM
By
KAUSHAL KUMAR SAHU
Assistant Professor (Ad Hoc)
Department of Biotechnology
Govt. Digvijay Autonomous P. G. College
Raj-Nandgaon ( C. G. )
CONTENT
 INTRODUCTION OF PLASMA MEMBRANE
 MODEL OF PLASMA MEMBRANE
 TRANSPORT OF SMALL MOLECULE
 PASSIVE TRANSPORT
 TYPE ( DIFFUSION, FACILITATED)
 MECHANISM
 REFRENCES
PLASMA MEMBRANE
Cytoplasm enclosed by a layer is called as plasma
membrane.
 This term was first coined by C.NAGELI & C.CRAMER
(1855).
 IN 1925, Two Dutch Scientist EDWIN GORTER &
F.GRENDEL extracted membrane lipid from red blood cell
corresponding to the surface of plasma membrane..
 Plasma membrane is selectively permeable membrane.
 Membrane maintain the equilibrium between the two
compartment & act as a barrier.
 Membrane made up of phospholipids bi-layer, protein,
carbohydrate.
FLUID MOSIC MODEL
Transport Of Small Molecule
PASSIVE TRANSPORT
 Net movement of substance across the
membrane without requirement of ATP.
 The activity of a cell depend on the
material that enter or leave the cell.
 To stay alive a cell must exchange
material such as food, oxygen, water with
it surrounding.
TYPE OF PASSIVE TRANSPORT
Simple
diffusion
Facilitated
diffusion
SIMPLE DIFFUSION
OSMOSIS
TONICITY
PLASMOLYSIS
FACTOE AFFECT DIFFUSION RATE
 Concentration
 Temperature
 Molecular size
 Viscosity
SIGNIFICATION OF OSMOSIS
 Plant absorbed water from the soil by root
& root hair through osmosis.
 Water move amongst the cell on the
principle of osmosis.
 Osmosis control the opening & closing of
stomata.
 Osmosis maintain the turgidity of leaves.
FACILITATED DIFFUSION
 The small molecule use carrier protein to
cross the membrane is called Facilitated
Diffusion.
 Transport can be carried out by:
Carrier protein & Ion channel.
NO need of requirement of ATP.
TRANSPORT OF GLUCOSE
 Glucose bind with
protein.
 Conformation change
takes place.
 Glucose releases
inside the cell.
 Return to their
original conformation.
ION CHANNEL
 Transport through channel is extremely rapid,
more than a million ions per second flow
through open channel.
 Ion channel are highly selective because narrow
pore in the channel restrict the passage of ion.
 Most ion channel are not permanent open ,its
opening & closing is regulated gate.
 Gate can be:
 Voltage-gate channel.
 Ligand –gate channel.
REFERENCES
 Geoffrey M. Cooper , Robert E. Hausman (2007) The Cell
Molecular Approach. 4rth Edition
Published By :Sinauer Association, Inc.
 Gupta And Jangir (1998) The Cell Biology Fundamental
Application
Published By : Agro Botanica.
 E.E.P De Robert, E.M.F De Robert (1995) Cell And
Molecular Biology 8th Edition
Published By: B.I. Waverly Pvt. Ltd.
Wikipedia .com /passive transport .html

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Transport of small molecule across cell membrane By KK Sahu Sir

  • 1. TRANSPORT OF SMALL MOLECULE ACROSS CELL MEMBRANE: PASSIVE MECHANISM By KAUSHAL KUMAR SAHU Assistant Professor (Ad Hoc) Department of Biotechnology Govt. Digvijay Autonomous P. G. College Raj-Nandgaon ( C. G. )
  • 2. CONTENT  INTRODUCTION OF PLASMA MEMBRANE  MODEL OF PLASMA MEMBRANE  TRANSPORT OF SMALL MOLECULE  PASSIVE TRANSPORT  TYPE ( DIFFUSION, FACILITATED)  MECHANISM  REFRENCES
  • 3. PLASMA MEMBRANE Cytoplasm enclosed by a layer is called as plasma membrane.  This term was first coined by C.NAGELI & C.CRAMER (1855).  IN 1925, Two Dutch Scientist EDWIN GORTER & F.GRENDEL extracted membrane lipid from red blood cell corresponding to the surface of plasma membrane..  Plasma membrane is selectively permeable membrane.  Membrane maintain the equilibrium between the two compartment & act as a barrier.  Membrane made up of phospholipids bi-layer, protein, carbohydrate.
  • 6. PASSIVE TRANSPORT  Net movement of substance across the membrane without requirement of ATP.  The activity of a cell depend on the material that enter or leave the cell.  To stay alive a cell must exchange material such as food, oxygen, water with it surrounding.
  • 7. TYPE OF PASSIVE TRANSPORT Simple diffusion Facilitated diffusion
  • 12. FACTOE AFFECT DIFFUSION RATE  Concentration  Temperature  Molecular size  Viscosity
  • 13. SIGNIFICATION OF OSMOSIS  Plant absorbed water from the soil by root & root hair through osmosis.  Water move amongst the cell on the principle of osmosis.  Osmosis control the opening & closing of stomata.  Osmosis maintain the turgidity of leaves.
  • 14. FACILITATED DIFFUSION  The small molecule use carrier protein to cross the membrane is called Facilitated Diffusion.  Transport can be carried out by: Carrier protein & Ion channel. NO need of requirement of ATP.
  • 15. TRANSPORT OF GLUCOSE  Glucose bind with protein.  Conformation change takes place.  Glucose releases inside the cell.  Return to their original conformation.
  • 16. ION CHANNEL  Transport through channel is extremely rapid, more than a million ions per second flow through open channel.  Ion channel are highly selective because narrow pore in the channel restrict the passage of ion.  Most ion channel are not permanent open ,its opening & closing is regulated gate.  Gate can be:  Voltage-gate channel.  Ligand –gate channel.
  • 17. REFERENCES  Geoffrey M. Cooper , Robert E. Hausman (2007) The Cell Molecular Approach. 4rth Edition Published By :Sinauer Association, Inc.  Gupta And Jangir (1998) The Cell Biology Fundamental Application Published By : Agro Botanica.  E.E.P De Robert, E.M.F De Robert (1995) Cell And Molecular Biology 8th Edition Published By: B.I. Waverly Pvt. Ltd. Wikipedia .com /passive transport .html