A solution is a homogeneous mixture of two or more substances where a solute is dissolved in a solvent. The concentration of a solution refers to the amount of solute dissolved in a fixed amount of solvent. Solutions can be dilute, containing a small amount of solute, or concentrated, containing a large amount of solute. Soft drinks are considered solutions but contain many unhealthy additives like sugar, artificial sweeteners, caffeine, carbon dioxide, preservatives, artificial flavors, colorings, and sodium. Long term consumption of soft drinks can increase risks of diseases, cancer, and other health issues.
I Hope You all like it very much. I wish it is beneficial for all of you and you can get enough knowledge from it. Clear and appropriate objectives, in terms of what the audience ought to feel, think, and do as a result of seeing the presentation. Objectives are realistic – and may be intermediate parts of a wider plan.
Molarity vs Molality What is molarity? Molarity is also known as molar concentration, it is the ratio of moles of substance to volume in liter. Where mole is weight in gram divided by molecular weight. Molarity is chemistry terminology. Molarity... read more at https://chemistrynotesinfo.com/molarity-vs-molality/
Introduction to redox reactions
References
Tindale, Ritchie et al, 2014, Chemistry for CSEC 2nd Edition, Nelson Thornes. p156-159
Electron Transfer in Redox Reactions Todayhttps://www.sewanhakaschools.org
I Hope You all like it very much. I wish it is beneficial for all of you and you can get enough knowledge from it. Clear and appropriate objectives, in terms of what the audience ought to feel, think, and do as a result of seeing the presentation. Objectives are realistic – and may be intermediate parts of a wider plan.
Molarity vs Molality What is molarity? Molarity is also known as molar concentration, it is the ratio of moles of substance to volume in liter. Where mole is weight in gram divided by molecular weight. Molarity is chemistry terminology. Molarity... read more at https://chemistrynotesinfo.com/molarity-vs-molality/
Introduction to redox reactions
References
Tindale, Ritchie et al, 2014, Chemistry for CSEC 2nd Edition, Nelson Thornes. p156-159
Electron Transfer in Redox Reactions Todayhttps://www.sewanhakaschools.org
As the world becomes more connected, we have greater access to information than we could have thought possible only a few years ago. This has had a tremendous impact on education, and English teaching is no exception. From greater education and training requirements to a growing emphasis on the use of technology both in and outside the classroom, how can teachers keep up with the pace of change? This talk will discuss current and future trends in teaching and give teachers ideas about how they can stay informed and professionally up-to-date in today’s fast-paced world.
Educational issues in the context of urbanization, globalization and privatiz...Hathib KK
It deals: what is urbanization? What are the positive impact of urbanization on education? what are the negative impact of urbanization on education? What is globalization? What is the positive impact of globalization on education? what is the negative impact of globalization on education? What is privatization? what is the positive impact of privatization on education?What is the negative impact of privatization on education?
Serenity Health information series # 12 KIDNEY STONESMICHELLE Edmonds
MIND Emotional Cause: √Lumps of undissolved anger
BODY
√Uva Ursi Tea
√Dandelion Root as a tea
√Youngevity OSTEO Liquid
Calcium with Minerals-binds w/
Oxalate which makes most stones
√Focus on Serenity’s week #1
Fresh GREEN juices
SPIRIT
√Think about primary root
of your anger
√Pray and ask GOD to help you
rechannel the anger positively,
so you can release it
Dehydration occurs when your body is unable to retain fluids and electrolytes. When there is a reduction in the water content of the body, the salt-sugar balance goes haywire, which affects the functioning of the body. There are many factors that cause dehydration
Hello everyone,
The aim of this powerpoint presentation is to raise the self awareness concerning th use of sugar. If you want to leave longer , you just have to omit sugar from your life !
I hope you will enjoy my humble work :)
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
2. A solution is a
homogeneous mixture
composed of two or
more substance.In
such a mixture a
solute is a substance
dissolved in another
substance known as
solvent.
3. CONCENTRATION OF A SOLUTION
• It refers to the amount of solute dissolved in a fixed
amount of solvent.
•A solution containing a small amount of solute is
known as dilute solution
•A solution containing large amount of solute is
known as concentrated solution.
4.
5.
6. MIXTURES
• All solutions are mixtures.
•Mixtures are of two types ;
A)Homogeneous Mixture
A mixture which has uniform composition and
properties throughout. For example, air is ahomogeneous
mixture of gases. A teaspoonful of table salt stirred into a
glass of water also makes a homogeneous mixture.
B)Heterogeneous Mixture
A heterogeneous mixture is simply any mixture that
is not uniform in composition – it's a non-uniform mixture of
smaller constituent parts. Using various means, the parts in
the mixture can be separated from one another.
Eg:Cereal in milk is anexample of a heterogeneous mixture.
Soil is another example. Soil has pebbles, plant matter and
sand in it.
7.
8. TRUE SOLUTION
A true solution is a homogeneous solution in which the solute
particles have diameters less than 10-7cm. i.e., the solute
particles are of molecular dimensions. The particles are
invisible even under powerful microscopes. For example,
sodium chloride in water is a true solution.
COLLOID
A colloid is a solution that has particles ranging between 1 and
1000 nanometers in diameter, yet are still able to remain evenly
distributed throughout the solution. These are also known
as colloidal dispersions because the substances remain
dispersed and do not settle to the bottom of the container.
SUSPENSION
A suspension is a heterogeneous mixture in which solute-like
particles settle out of a solvent-like phase some time after their
introduction.
We apply the word 'suspension' when particles are big enough
to eventually settle. We use the terms 'solute-like' and 'solvent-
like,' because we are dealing with a heterogeneous mixture,
while the terms solute and solvent refer to solutions, which
are homogeneous.
9.
10.
11.
12.
13.
14.
15. SOFT DRINKS
•Soft drinks” is a term used for beverages that don’t contain
alcohol (“hard” liquor). If you really know what the contents
of soft drinks are, you would not think it is “soft”. It is really
“hard” on your health.
•Soft drinks have become so much a part of
modern living, especially in major cities around the
world. It particularly appeals to the younger
generation who drinks soft drinks in place of
water.
•Soft drinks advertisements target young people
who are oblivious to the harm these drinks can do
to their bodies. No wonder the people love
drinking soft drinks too–they give the refreshing
feeling and seem to quench thirsts on a blistering
hot day. Vending machines are making the
“killing” easier.
16. soft drinks contain:
•SUGAR
•A majority of soft drinks contain large amounts of
refined sugar content of up to 15 teaspoons each in a
325 ml can. One can a day gives you more sugar than
is necessary for your body.
•Sugar erodes teeth, increases your
risks of diabetes, heart disease,
indigestion and skin problems. As
sugar enters the bloodstream and
increases the sugar level rapidly, it
causes a dependency situation
whereby the body craves for a
constant flow of sugar to maintain
its levels. This keeps you craving for
more, creating a vicious cycle that
gets you hooked.
17. ARTIFICIAL SWEETENERS
Soft drinks disguised as “diet soda” or “tonic water” contain
calorie-reduced sweeteners such as aspartame, acesulfame-K,
saccharin or sucralose.
Aspartame is 200 times sweeter than sugar, so very little is used
to sweeten the soft drink. It does enhance the taste of the drink but
it also cause numerous adverse side-effects. Common complaints
include migraine, memory loss, emotional disorders, blurred vision,
ringing in the ears, heart palpitations and shortness of breath.
Acesulfame-K (Ace-K)is 100-200 times sweeter than sugar,
with a slight bitter after-taste. Initial tests have indicated that this
substance may be carcinogenic. Even though thorough tests are still
incomplete, there are reasons to be careful not to ingest this
compound as tests on lab animals have shown rapid increase in
cancerous tumors.
Saccharin is a non-nutritive sweetener which is 300 times
sweeter than sugar. It has been proven to cause bladder cancer and
is banned in Canada, New Zealand and several European countries.
Saccharin is found to be present in Pepsi Diet, Diet Coke and Diet
Sarsi.
18. CAFFEINE
Caffeine is an addictive drug that enhances the soda
flavor. It artificially stimulates the nervous system
and increases the heart rate. When consumed, it may
temporarily arouse the intellect and diminish fatigue.
Over-stimulation depletes the body of vital energy as
it struggles to deal with the toxin that enters the
bloodstream. Excessive caffeine consumption is
linked to cancers of the bladder and stomach, raised
blood pressure and aggravating diabetes symptoms.
Worst of all, it may even contribute to birth defects in
babies.
Drinking soft drinks after a physical workout can
cause calcium and potassium loss which in turn can
cause sore muscles and delayed recovery time after
exercise.
19. CARBON DIOXIDE
Carbonated drinks are made by injecting
carbon dioxide into the water under pressure. The
more carbon dioxide injected, the lower the pH, the
more acidic it gets, the more fizzy it is.
We all know that carbon dioxide is a waste
product exhaled by human. We don’t need carbon
dioxide, so why are we taking it by drinking soft
drinks? Too much carbon dioxide kills healthy cells.
Dead cells cause an acidic environment. As
mentioned above, in an acidic environment, some
cells may survive by becoming abnormal
malignant cells.
20. PRESERVATIVES
Preservatives are added into soft drinks to prevent
spoilage, and to prolong shelf life. Storage
conditions and time can affect the taste and flavor,
and these preservatives help to preserve that.
The labels may list these as “permitted
preservatives” but the exceeded amount can cause
untold number of health problems.
Sodium benzoate (a.k.a. benzoic acid) is present in
most soft drinks. This chemical is known to cause
asthma, rashes and hyperactivity.
Sulphur dioxide is also used in some soft drinks to
preserve the color of say, carbonated lemon juice
from turning brown. This chemical is used for
industrial bleaching. It is so toxic that repeated
exposures to it can cause fainting spells, skin
eruptions, swelling, tightening of the chest, shock,
coma and even death.
21. ARTIFICIAL FLAVORINGS AND
COLORINGS
Artificial flavorings are commonly used in making
soft drinks to give each flavor its distinctive taste. These
have adverse effect on hyperactive children and must be
eliminated from their diet.
Tartrazine is an orange-yellowish drink coloring that is
banned in Norway and Finland. It can cause allergic
reactions like skin rashes, swelling, excessive mucus and
bloodshot eyes.
Carmoisine is a reddish drink coloring that is banned in
the US and Canada. It can cause allergic reactions, food
poisoning and even cancer.
Brilliant Blue is another cancer-causing agent that is now
banned in many developed countries. Sadly, it is still being
used in my country to produce soft drinks. This chemical
can cause chromosomal damage and allergic reactions.
22. SODIUM
Most soft drinks contain some inorganic
sodium. Sodium is used as an
emulsifying, stabilizing and thickening
agent to ensure that the contents of the
drinks are kept evenly distributed.
Excessive consumption of inorganic
sodium thickens and stiffens arteries,
leading to stroke, cardiac failure, high
blood pressure and many other
diseases.