This paper analyzes whether technical change is skill-biased when accounting for international fragmentation of production. Using data from the World Input Output Database, the authors estimate factor cost shares across 280 manufacturing industries and 20 countries from 1995-2007. Their results from translog cost function regressions provide support for skill-biased technical change, with high-skilled labor and capital showing positive and significant coefficients, while low-skilled and medium-skilled labor show negative coefficients. The findings are robust across specifications and imply cumulative biases over the period in favor of high-skilled labor and capital, and against low-skilled labor. The discussant comments that this makes a significant contribution but raises questions around the use of a Leontief