Pulse Polio is an immunisation campaign established by the government of India to eliminate poliomyelitis (polio) in India by vaccinating all children under the age of five years against the polio virus.
This ppt contains all the information about Revised NationalTuberculosis Control programme (RNTCP) It is useful for students of the medical field learning Preventive and social medicine, Swasthavritta (Ayurved) and everyone who is interested in in knowing about it.
Pulse Polio is an immunisation campaign established by the government of India to eliminate poliomyelitis (polio) in India by vaccinating all children under the age of five years against the polio virus.
This ppt contains all the information about Revised NationalTuberculosis Control programme (RNTCP) It is useful for students of the medical field learning Preventive and social medicine, Swasthavritta (Ayurved) and everyone who is interested in in knowing about it.
A decentralized system of disease surveillance for timely and effective public health action with a focus on functional integration of surveillance components of various vertical programmes.
Universal Immunization Program is a vaccination program launched by the Government of India in 1985.
It became a part of Child Survival and Safe Motherhood Program in 1992 and is currently one of the key areas under National Rural Health Mission(NRHM) since 2005.
Program consists of vaccination for 12 diseases -
Tuberculosis
Diphtheria
Pertussis
Tetanus,
Poliomyelitis,
Measles,
Hepatitis B,
Diarrhea,
Japanese-Encephalitis,
Rubella,
Pneumonia
Pneumococcal diseases
This ppt gives you the details about the NRHM scheme. The SWOT analysis has been done which helps you to know the strength and weakness part of the NRHM program.
BY: Dr.Pavithra R (M.H.A)
Polio is a viral disease that destroys the nerve cells present in the spinal cord causing paralysis or muscle weakness to some part of the body.
Pulse Polio Programme was launched in 1995 after a resolution for a global initiative of polio eradication was adopted by World Health Assembly (WHA) in 1988.
A decentralized system of disease surveillance for timely and effective public health action with a focus on functional integration of surveillance components of various vertical programmes.
Universal Immunization Program is a vaccination program launched by the Government of India in 1985.
It became a part of Child Survival and Safe Motherhood Program in 1992 and is currently one of the key areas under National Rural Health Mission(NRHM) since 2005.
Program consists of vaccination for 12 diseases -
Tuberculosis
Diphtheria
Pertussis
Tetanus,
Poliomyelitis,
Measles,
Hepatitis B,
Diarrhea,
Japanese-Encephalitis,
Rubella,
Pneumonia
Pneumococcal diseases
This ppt gives you the details about the NRHM scheme. The SWOT analysis has been done which helps you to know the strength and weakness part of the NRHM program.
BY: Dr.Pavithra R (M.H.A)
Polio is a viral disease that destroys the nerve cells present in the spinal cord causing paralysis or muscle weakness to some part of the body.
Pulse Polio Programme was launched in 1995 after a resolution for a global initiative of polio eradication was adopted by World Health Assembly (WHA) in 1988.
On 19 November 1985, GOI renamed EPI program, modifying the schedule as ‘Universal Immunization Program’ dedicated to the memory of Late Prime Minister Mrs Indira Gandhi.
UIP has two vital components: immunization of pregnant women against tetanus, and immunization of children
Nigeria's National Programme on ImmunisationEsther Ajari
This presentation gives a well-researched overview of Nigeria's National Programme on Immunization. The key areas covered include: Definition of terminologies, history, components, controversies, strategies, and guidelines.
A zoonosis is an infectious disease that has jumped from a non-human animal to humans. Zoonotic pathogens may be bacterial, viral or parasitic, or may involve unconventional agents and can spread to humans through direct contact or through food, water or the environment
COMMUNITY HEALTH NURSING-II
HEALTH PLANNING POLICIES AND
PROBLEMS.To address the unmet needs for contraception, health care infrastructure and health personnel and to provide integrated service delivery for basic reproductive and child health care.
To bring the TFR to replacement level by 2010, through vigorous implication of inter-sectorial operational strategies.
To bring the TFR to replacement level by 2010, through vigorous implication of inter-sectorial operational strategies.
To achieve a stable population by 2045, at a level consistent with the requirements of sustainable economic growth, social development and environmental protection
Address the unmet needs for basic reproductive and child health services, supplies and infrastructure.
Make school education up to age 14 free and compulsory, and reduce drop outs at primary and secondary school levels to below 20 percent for both boys and girls.
Reduce infant mortality rate to below 30 per 1000 live births.Reduce maternal mortality ratio to below 100 per 100,000 live births.
Achieve universal immunization of children against all vaccine preventable diseases
Promote delayed marriage for girls, not earlier than age 18 and preferably after 20 years of age.
Achieve 80 percent institutional deliveries and 100 percent deliveries by trained persons.
Achieve universal access to information/counseling, and services for fertility regulation and contraception with a wide basket of choices.
Achieve 100 per cent registration of births, deaths, marriage and pregnancyContain the spread of Acquired Immunodeficiency Syndrome (AIDS), and promote greater integration between the management of reproductive tract infections (RTI) and sexually transmitted infections (STI) and the National AIDS Control Organisation.
Prevent and control communicable diseasesIntegrate Indian Systems of Medicine (ISM) in the provision of reproductive and child health services, and in reaching out to households.
Promote vigorously the small family norm to achieve replacement levels of TFR.
Bring about convergence in implementation of related social sector programs so that family welfare becomes a people centered programme.Decentralized planning and programme implementation
Convergence of service delivery at village level
Empowering women for improved health and nutrition
Child health and survival
Meeting the unmet needs for family welfare services
Underserved population groups(urban slums, tribals, hill areas, adolescents)
Diverse health care providers
Collaboration with and commitments from non government organisations and private sector
Mainstreaming Indian systems of medicine and Homeopathy
A National Commission on Population, presided over by the Prime Minister, will have the Chief Ministers of all states and UTs, and the Central Minister in charge of the Department of Family Welfare and other concerned Central Ministries and Departments reputed demographers, public health professionals, and NGOs as members.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYNEHA GUPTA
The process of drug discovery and development is a complex and multi-step endeavor aimed at bringing new pharmaceutical drugs to market. It begins with identifying and validating a biological target, such as a protein, gene, or RNA, that is associated with a disease. This step involves understanding the target's role in the disease and confirming that modulating it can have therapeutic effects. The next stage, hit identification, employs high-throughput screening (HTS) and other methods to find compounds that interact with the target. Computational techniques may also be used to identify potential hits from large compound libraries.
Following hit identification, the hits are optimized to improve their efficacy, selectivity, and pharmacokinetic properties, resulting in lead compounds. These leads undergo further refinement to enhance their potency, reduce toxicity, and improve drug-like characteristics, creating drug candidates suitable for preclinical testing. In the preclinical development phase, drug candidates are tested in vitro (in cell cultures) and in vivo (in animal models) to evaluate their safety, efficacy, pharmacokinetics, and pharmacodynamics. Toxicology studies are conducted to assess potential risks.
Before clinical trials can begin, an Investigational New Drug (IND) application must be submitted to regulatory authorities. This application includes data from preclinical studies and plans for clinical trials. Clinical development involves human trials in three phases: Phase I tests the drug's safety and dosage in a small group of healthy volunteers, Phase II assesses the drug's efficacy and side effects in a larger group of patients with the target disease, and Phase III confirms the drug's efficacy and monitors adverse reactions in a large population, often compared to existing treatments.
After successful clinical trials, a New Drug Application (NDA) is submitted to regulatory authorities for approval, including all data from preclinical and clinical studies, as well as proposed labeling and manufacturing information. Regulatory authorities then review the NDA to ensure the drug is safe, effective, and of high quality, potentially requiring additional studies. Finally, after a drug is approved and marketed, it undergoes post-marketing surveillance, which includes continuous monitoring for long-term safety and effectiveness, pharmacovigilance, and reporting of any adverse effects.
3. LESSON OBJECTIVE
At the end of the class the learner
should be able to:
1. Explain in detail Universal
Immunization Programme
2. Explain It’s focus and
implementation strategies
3. Enumerate the preventive
measures for preventing
Vaccine Preventable Disease
7. HISTORY
14 May 1796 - Jenner inoculated
James Phipps, an 8 yr old boy with
cowpox lymph taken from Sara
Nelms, a milkmaid.
Boy recovered after a brief illness
8. Jenner inoculated pus taken from a small pox
patient.
Boy showed no reaction.
Jenner recommended vaccination for prevention
of smallpox
9. Smallpox vaccination being a safe, simple,
effective and inexpensive procedure, gained
universal acceptance.
Main instrument for eradication for smallpox at
global level.
Small pox has since been eradicated but Jenner
lives for ever.
13. The first vaccine having been sent by jenner
himself and used in bombay in 1802.
The pilot projects began during 1960.
WHO certified India to be free of smallpox in
march 1977.
The global eradication of smallpox is arguably
the greatest achievement of twentieth century
medicine
15. VPD
An infectious disease for which an
effective preventive vaccine exists.
If a person dies from it, the death is
considered a vaccine-preventable
death.
28. FULLY IMMUNIZED CHILD
A child who received One dose of
BCG, Three doses of DPT and OPV
One dose of measles before one year
of age.
This gives a child the best chance for
survival
29. MILESTONES IN THE
IMMUNIZATION PROGRAM IN
INDIA
1978: Expanded Program of Immunization (EPI)
introduced after smallpox eradication: BCG, DPT,
OPV, Typhoid.
Limited to mainly urban areas
30. 1985 : Universal Immunization Program (UIP)
introduced; Expanded to entire country; Measles
added.
1990 : Vitamin-A supplementation.
1992: Child Survival and Safe Motherhood
Program.
31. 1995: Polio National Immunization Days.
1997: Reproductive and Child Health
Program (RCH I).
2005 : RCH-II and the National Rural Health
Mission (NRHM).
33. EXPANDED…
Adding more disease controlling antigens
to vaccination schedules.
Extending coverage to all corners of a
country.
Spreading services to reach the less
privileged sectors of the society
34. 1978 – PRIMARY HEALTH
CONCEPT
ALMA – ATA declaration included
immunization as one of the strategies
for achieving HFA by 2000 AD.
WHO named this immunization
programme as EXPANDED
PROGRAMME ON IMMUNIZATION.
35. 1985 – UNICEF re named it as “UNIVERSAL
IMMUNIZATION PROGRAMME”.
There is no difference between both the prog.
36. The goal was to achieve universal immunization by 1990.
EPI is regarded as an instrument of UPI.
37. EPI IN INDIA 1978
The Govt of India launched it’s EPI in 1978.
The objective was to reducing mortality,
morbidity resulting from VPDs.
To achieve a self sufficiency in vaccine
production.
38. EPI IN INDIA 1978
BCG, OPV, DPT & Measles- under 5
children.
TT- pregnant women.
Typhoid added.
OPV- 1979.
40. The UIP was taken up in 1986 as National
Technology Mission & became operational in all
districts in the country during 1989-90.
UIP become a part of the Child Survival and Safe
Motherhood (CSSM) Programme in 1992 and
Reproductive and Child Health (RCH)
Programme in 1997.
41. COMPONENTS OF UIP
1. Immunization of pregnant women
against tetanus.
2.Immunization of children in their first
year of life against 6 VPDs.
43. 3. The aim was to achieve 100 % coverage of
pregnant women with 2 doses of TT.
& at least 85% coverage of children under one
year (with 3 doses of DPT, OPV & one dose of
BCG, One dose of MMR) by 1990
44. UIP was first taken up in 30 selected districts &
catchment areas of Medical Colleges.
A technology Mission on Vaccination &
Immunization of Vulnerable Population was set
up to focus on all aspects of immunization
activity.
48. Though the target was 100% coverage no country
in the world has reached the coverage figure.
Therefore it can be interpreted as “NO CHILD
SHOULD BE DENIED OF IMMUNIZATION” .
51. COMPONENTS:
1.Support for alternative vaccines
delivery from PHC to HSc & out reach
sessions.
2.Deploying retired manpower to
implement vaccination services in
urban slums & underserved areas
52. 3. Mobility support to Dist Immunization
Officer.
4. Reviewing meeting at state level with the
districts at 6 monthly intervals.
5. Training of ANM, cold chain handlers, mid
level managers, refrigerator machines.
59. STATUS FEB 2012
INDIA is removed from the list of
“POLIO ENDEMIC COUNTRIES”
60. REFERENCES
1.Park’s Textbook of Preventive & Social Medicine,
Banarsidas Bhanot publishers,22 Ed
2. Basawanthappa B.T, Community Health Nursing,
Jayapee publications
3. Neelam Kumari, Text book of Community Health
Nursing, S. Vikas Publisher, First Edn
4. Rao.B sridhar, Book of Community Health
Nursing,AITBS publisher, New Delhi
61.
62. EXPECTED QUESTIONS
SHORT NOTES:
EXPANDED PROGRAMME ON
IMMUNIZATION
PULSE POLIO PROGRAMME
SHORT ANSWER
IMMUNIZATION SCHEDULE FROM
BIRTH TO UNDER FIVE