1. The document provides an overview of common pediatric surgical conditions, including congenital diaphragmatic hernia, esophageal atresia with tracheoesophageal fistula, congenital hypertrophic pyloric stenosis, intussusception, Meckel's diverticulum, Hirschsprung disease, and anorectal malformations. 2. It describes the definition, etiology, pathophysiology, clinical presentation, diagnostic workup, and management of each condition. Diagrams and images are provided to illustrate key aspects. 3. The review is intended for 6th year medical students to familiarize them with important pediatric surgical topics.

1. Paediatric Surgery ReviewPaediatric Surgery Review
(for 6(for 6thth
year medical students)year medical students)
Mustafa RedwanMustafa Redwan
Assistant Lecturer of General &Assistant Lecturer of General &
Paediatric SurgeryPaediatric Surgery
Sohag Faculty of MedicineSohag Faculty of Medicine
20132013

2. OutlineOutline
• Congenital Diaphragmatic Hernia (CDH)
• Esophageal Atresia &/Tracheo-esophageal fistula
(EA -TEF)
• Congenital Hypertrophic Pyloric Stenosis(CHPS)
• Intussuception
• Meckel’s Diverticulum
• Hirschsprung Disease (HSD)
• Anorectal Malformations (ARM)
• Intestinal Malrotation.

3. 1-Congenital Diaphragmatic1-Congenital Diaphragmatic
HerniaHernia
(CDH)(CDH)

4. • Herniation of abdominal contents into the chest
through a congenital defect in the diaphragm.
• Aetiology & Embryology: failure of fusion of the
septum transversum w the dorso-lateral
diaphragmatic processes(pleuro-peritoneal
membranes)
• Types :
-Posterior (Bochdalek) 90% , lt 5x >Rt
-Anterior (Morgagni)
-Eventration (just weakness & upward eversion of
the diaphragm with no actual defect)
DefinitionDefinition

5. Schematic illustration of a left congenital diaphragmatic
hernia showing translocation of abdominal viscera through
a posterolateral aperture into the chest.

6. -Ipsilateral lung hypoplasia & cyanosis
-Contralateral lung compression
-Pulmonary hypertension & Rt to Lt
shunting(Persistent fetal circulation)
-Ischemia of herniated bowel
Pathophysiology:Pathophysiology:

7. DiagnosisDiagnosis
• Antenatal diagnosis:
-Maternal polyhydramnios
-U/S
• After birth:
Severe cases :
immediate severe RD ,cyanosis & gasping
Unequal air entry
Shifted heart sounds
Scaphoid abdomen
Mild cases (delayed diagnosis)
Recurrent chest infections
Accidental auscultation of bowel sounds

8. InvestigationsInvestigations
• Chest X-ray
• Arterial Blood gases
• Echocardiogram
• Ultrasound
• CT chest

11. DD:DD:
• Other causes of respiratory distress
Mention…………?

12. ManagementManagement
• Preop. Care:
1-NG tube
2-ET intubation & ventilation
3-I.V fluids
4-Warming
5-NICU admission

13. Operation :Operation :
1-Abdominal approach (Subcostal incision)
2-Reduction of the content
3-Repair of the defect

14. A.Schematic drawing of an unreduced left congenital diaphragmatic hernia as seen
from the abdomen. B, The same hernia but now reduced, Sutures have been placed
for a primary repair. C, Completed primary repair of a left congenital diaphragmatic
hernia D, Repaired left congenital diaphragmatic hernia using prosthetic material.

15. Postop.Care:Postop.Care:
Continued ventillatory support

16. 2-Esophageal Atresia &2-Esophageal Atresia &
Tracheoesophageal FistulaTracheoesophageal Fistula
(EA & TEF)(EA & TEF)

17. Definition:Definition:
• Esophageal atresia (EA) is an interruption or
discontinuity
• Tracheoesophageal fistula (TEF) is an abnormal
communication
• EA may be present with or without a TEF.
• TEF may be present with or without EA.

18. Aetiology:Aetiology:
• Incomplete partitioning of primitive foregut

19. Types of EA & TEF:Types of EA & TEF:

20. PathophysiologyPathophysiology
• Failure of swallowing….dehydration &
hypoglycemia
• Proximal obstruction….Aspiration
• Distal fistula…..regurgitation of acid into
the stmoach……..Severe pneumonia

21. DiagnosisDiagnosis
• Maternal history of polyhydramnios.
• Excessive salivation, drooling ,coughing,choking
cyanosis during the first oral feeding.
• Chemical and aspiration pneumonia
• The inability to pass a nasogastric tube into the stomach
• X-ray: -coiling of the tube in the upper mediastinum.
-gastrointestinal gas ??
• contrast study
• TEF w/o atresia presents with recurrent aspiration

22. Search forSearch for {{ VACTERLVACTERL }}
Vertebral
Anorectal
Cardiac
Tracheal Present in 50% of cases.
Esophageal
Renal
Limb
So that,other investigations may be done as
required e.g: abd. U/S ,Echo,X-ray spine…etc.

23. ManagementManagement
1-Preoperative preparation1-Preoperative preparation
•Oral feeding prohibited
•Continuous suction
•NICU admission:
Supine and elevated to 30 ～ 40º
incubator,oxygen inhalation, Endotracheal
tube distal to the TEF minimize the leak and
permit adequate ventilation.
•I.V fluids and broad-spectrum antibiotics
•Exclude VACTERL.
•Urgent surgical repair after rapid preoperative
preparation

24. • Low-risk infants should get primary repair :
• high-risk babies get gastrostomy
• Rt thoracotomy through the 4th
intercostal space.
• Operation includes TEF ligation, transection, and
restoration with end-to-end anastamosis over a
ryle tube.
• An ICT is inserted in the Rt pleural space.
• POD 5-7 esophagram, if no leak, feed, remove
drain.
2-Operation2-Operation

25. ComplicationsComplications
• Early complications :
Anastamotic leak,
recurrent TEF,
tracheomalacia.
• Late Complications :
Anastamotic stricture (25%),
reflux (50%),
dysmotility (100%).

26. 3-Congenital Hypertrophic3-Congenital Hypertrophic
Pyloric StenosisPyloric Stenosis
CHPSCHPS

27.  Common.Common.
 Between the ages of 2 and 8 weeks.Between the ages of 2 and 8 weeks.

28. PathophsiologyPathophsiology::
-Muscular hypertrophy of all the layers of-Muscular hypertrophy of all the layers of
the pylorus , most significant in the circularthe pylorus , most significant in the circular
layer, causing pyloric stenosis &layer, causing pyloric stenosis &
-Gradual gastric outlet obstruction(GOO).-Gradual gastric outlet obstruction(GOO).
-Repeated Vomiting….losses of …-Repeated Vomiting….losses of …
-increased peristalsis-increased peristalsis

29. Diagnosis:Diagnosis:
SymptomsSymptoms
-Onset:2-3 weeks after birth (not since birth)-Onset:2-3 weeks after birth (not since birth)
-Persistent Progressive Projectile Non-bilie stained-Persistent Progressive Projectile Non-bilie stained
vomiting.vomiting.
-hungry baby…..Feeds vigorously-hungry baby…..Feeds vigorously
Signs:Signs:
-General: dehydration, weight loss,oliguria,tinge of-General: dehydration, weight loss,oliguria,tinge of
jaundicejaundice
-Abdominal :-Abdominal :
distension of epigastrium,distension of epigastrium,
Visible gastric peristalsisVisible gastric peristalsis
Palpation of the pyloric tumorPalpation of the pyloric tumor (pathognomonic)

30. Investigations:Investigations:
1-Ultrsound: Diagnostic in most cases1-Ultrsound: Diagnostic in most cases
2-Barium meal: for cases with difficulty in diagnosis2-Barium meal: for cases with difficulty in diagnosis ：：
①①distention of the stomachdistention of the stomach
②②strong gastric wavesstrong gastric waves
③③elongated and narrow pyloric channel “String Sign”elongated and narrow pyloric channel “String Sign”
④④delayed gastric emptyingdelayed gastric emptying
3-Labs:3-Labs:
- Na,K,Ca ,Cl- Na,K,Ca ,Cl
-hypo-chloraemic metabolic alkalosis,-hypo-chloraemic metabolic alkalosis,
- Indirect hyperbilirubinemia (glucuronyl transferase- Indirect hyperbilirubinemia (glucuronyl transferase
deficiency)deficiency)

31. Pyloric Stenosis--USPyloric Stenosis--US

32. Barium meal

35. Management:Management:
1-Preoperative preparation:1-Preoperative preparation:
-Good hydration by I.V fluids-Good hydration by I.V fluids
-correction of electrolytes & metabolic-correction of electrolytes & metabolic
alkalosisalkalosis

36. Ramstedt`s pyloromyotomyRamstedt`s pyloromyotomy
-Transverse Rt upper abd. Incision-Transverse Rt upper abd. Incision
-Intraoperative finding:-Intraoperative finding:
Olive shaped mass which is:Olive shaped mass which is:
22 ～～ 3cm in length,3cm in length,
pale in colorpale in color
Feels like cartilage)Feels like cartilage)
-Incision in the anterosuperior surface-Incision in the anterosuperior surface
-Avoid perforation-Avoid perforation
2-Operation:2-Operation:

37. CHPSCHPS
Danger point

38. Pyloromyotomy (diagramatic)Pyloromyotomy (diagramatic)

39. Pyloromyotomy (Operative photos)Pyloromyotomy (Operative photos)
Pyloromyotomy Completed

40. 3-Postoperative:3-Postoperative:
 Infants are usually maintained on I.V fluidsInfants are usually maintained on I.V fluids
for few hours.for few hours.
 They are allowed to resume gradual oralThey are allowed to resume gradual oral
feeding at the same day and arefeeding at the same day and are
discharged within 24-48hdischarged within 24-48h

41. 4-INTUSSUSCEPTION

42. DEFINITION:
• The Invagination or telescoping of a proximal segment of bowel
(intussusceptum) into the lumen of a distal segment (intussuscipiens).
Intussusceptum
=proximal portion
Intussuscipens
=distal portion

43. INCIDENCE:
• Second most common cause of acute
abdominal pain in children following
appendicitis
• Found between 3 months to 2 years of
age, peaking at 5-7 months

44. AETIOLOGY:
 Idiopathic 90%
(Most are ileocolic)
 Lead point <10%
•Most common is Meckel’s diverticulum
•Other possibilities : polyps, hemangiomas,
lymphomas, cyst;appendix, intestinal neoplasm,
submucosal hemorrhage associated with
Henoch-Schönlein purpura, foreign body, ectopic
pancreatic or gastric tissue, and intestinal
duplication.
Hypotheses of etiologies:……..

45. PATHOPHYSIOLOGY
• The invaginated segment is carried distally by
peristalsis.
• Mesnetery and vessels become involved with the
intraluminal loop and are squeezed within the
engulfing segment causing venous congestion.
• Types: enteroenteric, enterocolic, and colocolic.

46. DIAGNOSIS:
1-CLINICALLY:
• Cramping abdominal pain in an otherwise healthy child.
• drawing the legs up during the pain episodes After some
time, the child becomes lethargic.
• Vomiting.
• Constipation although frequent bowel movements may
occur with the onset of pain.
• “currant jelly” stool :dark blood clots mixed with mucus,
• An abdominal mass. & Signe de Dance

47. CLASSIC TRIAD:
Colicky abdominal pain
-pulling knees up to abdomen
Sausage shaped Abdomina
Mass
-sausage shaped
“Red Currant Jelly” or bloody
stools
present in only 20-50% of cases

48. 2-IMAGING:
1-Abdominal X-Ray
Low sensitivity, high false negative rate
Can be negative in early IS
Uses:
-Diagnosis of intussusception
-Evaluating for risk of perforation before enema treatment
-Diagnosis of other diseases (SBO, LBO, volvulus)
•Radiographic signs of Intussusception:
target sign
crescent sign
absent liver edge sign (also called absence of the subhepatic angle)
bowel obstruction
May have a normal x-ray!

49. Where is
the target
sign?

50. Created by gas
trapped between
two layers of
intestinal wall
target sign

51. • An abdominal film showing
signs of small bowel
obstruction (multiple dilated
intestinal loops mainly in the
center of the abdomen with
vavulae coniventes)

52. • Erect film showing multiple
fluid levels in the small bowel

53. plain abdominal films cannot be used to
rule out intussusception
KEEP IN MIND…

54. 2-ULTRASOUND
•Used to diagnose IS and prevent unnecessary enemas
High sensitivity and specificity
No radiation exposure
Exclude other pathologies.
•Findings:
-target sign (transverse)
-sandwich sign (longitudinal)

55. TARGET SIGN
Central hyperechoic region (C) surrounded by hypoechoic and
homogeneous edge (bowel wall)

56. TARGET SIGN

57. SANDWICH SIGN
Cylindrical hyperechoic
center (C) that
continues from
intestinal lumen and is
surrounded on both
sides by hypoechoic
mesentary (M)

58. 3-BARIUM ENEMA

59. 4-CT SCAN
• Target sign is also seen in
CT.
• Can also see a sausage
shaped mass

60. MANAGEMENT:
1-RESUCITATION & PREOP.PREP.:
NPO
NG tube
I.V.fluids
Broad spectrum antibiotics.
Blood transfusion.

61. 2-REDUCTION ENEMA:
• When the clinical index of suspicion for intussusception is high,
hydrostatic reduction by contrast agent or air enema is the
diagnostic and therapeutic procedure of choice.
• Types of enemas
 Pneumatic (air enema)
 Hydrostatic (fluid enema)
 Barium Enema (fluid with contrast)

62. Barium Enema:

63. 3-SURGERY:
Exploration through a transverse supraumblical incision
- Viable intestines:Reduction by milking (with
appendectomy,excision of associated Meckel`s
diverticulum…)
-Gangrenous loop: Resection of the affected segment
with: -primary anastmosis
-proximal ileostomy or colostomy and distal
mucous fistula

64. Ileocecocolic intussusception containing viable
loop treated by milking and appendictomy

65. Neglected ileocecal intussusception with gangrenous
perforated intestines treated by resection and primary
anastmosis

66. 5-Hirschsprung’s Disease5-Hirschsprung’s Disease

67. Hirschsprung’s DiseaseHirschsprung’s Disease
• Neurogenic form of intestinal obstruction
• Absence of ganglion cells in the myenteric
and submucosal plexus
• Failure in relaxation of the internal anal
sphincter and affected bowel
• Upstream bowel becomes dilated
secondary to distal obstruction

68. Pathogenesis:Pathogenesis:
• Failure of neural crest cells to migrate caudally
• Aganglionosis begins at anorectal line
• 80% involve only rectosigmoid area
• 10% extend proximal to splenic flexure
• 10% involves the entire colon and part of small
bowel (Total colonic aganglionosis)
• Rarely involves entire gastrointestinal tract

69. Presentation:Presentation:
• Severe abdominal distention
• 95% - failure to pass meconium in first 24
hours life
• Bilious vomiting
• PR examination…gush of stools & gas
• Older children - constipation, failure to thrive
• 10-15% -Present with Hirschsprung’s
enterocolitis severe explosive diarrhea
,fever ,dehydration and abd distension.

70. a neonate with Hirschsprung’s Disease

71. DiagnosisDiagnosis
• Clinical
• Abdominal plain X-rays
• Barium Enema
• Rectal Biopsies
• Anal manometry

72. Hirschsprung’sHirschsprung’s

73. Abdominal X-ray (HSD)Abdominal X-ray (HSD)

74. HSDHSD

75. Barium EnemaBarium Enema
showing 3 differentshowing 3 different
zoneszones :-:-
-Spastic lower zone-Spastic lower zone
-funnel shaped middle-funnel shaped middle
zonezone
-markedly dilated proximal-markedly dilated proximal
(normal) colon(normal) colon

78. Barium EnemaBarium Enema
• Less sensitive for detecting
short and ultrashort segment HSD
total colon aganglionosis, and
disease of the newborn (Many newborns
do NOT show definitive transition zone but
only delayed evacuation of contrast)

79. Rectal biopsyRectal biopsy
• Submucosal suction biopsy
–Meissner’s submucosal plexus
• Full thickness rectal biopsy
–Auerbach’s myenteric plexus
• Acetylcholinesterase staining
–increased staining of neurofibrils

80. Anorectal manometryAnorectal manometry
• Absent rectoanal inhibitory reflex
• Lack of internal anal sphincter
relaxation in response to rectal
stretch

81. Management:Management:
1-Definitive repair:1-Definitive repair:
• Transanal Pull-through operations (in prone jack-knife
position)
The most commonly used is the Trans-anal
endorectal mucosal excision (Soave)
A transanal approach is usually sufficent but
abdominal incision is sometimes needed for
mobilization of long segment HSD or in older
children.
• Laparoscopic assissted transanal pullthrough
is a recent approach that uses laparoscopy for
mobilizing the colon , facilitating the procedure
and avoiding bdominal incision.

82. Laparoscopic Assissted transanal pullthrough : the affected
segment has been withdrawn through the anus after being
dissected free from its mesentry and blood vessels using
laparoscopy

83. Operative complicationsOperative complications
• Constipation.
• Stricture Formation.
• Leak at anastamosis.
• Postop Enterocolitis.
• Incontinence.

84. 2-Hirshsprung enterocolitis:
• It`s is a medical emergency requiring:
-Hospital admission and observation
-NPO
-I.V fluids
-Broad spectrum antibiotics and metronidazole
-Frequent colonic irrigation.
• Surgery is indicated in cases of :
-Failure of conservation.
-Evidence of bowel perforation
in the form of a leveling transverse or sigmoid
loop colostomy.

85. 6-Meckel’s Diverticulum6-Meckel’s Diverticulum

87. Meckel’s DiverticulumMeckel’s Diverticulum (Disease of 2 )(Disease of 2 )
• Found in 2% of the population.
• Symptomatizes in only 2% of affected people.
• Majority of symptomatic cases < 2yrs old
• 2 feet from ileocecal valve.
• About 2 inches in length.
• contains 2 types of ectopic tissue: gastric and/or
pancreatic.

88. Presentation:Presentation:
• Painless GI Bleeding (50%)
• Bowel Obstruction (30%)
• Inflammation – diverticulitis (20%)

89. GI Bleeding:GI Bleeding:
• Most common cause of bleeding in
children
• Painless, massive, usually self resolving
• Due to mucosal ulceration from acid
secretion

90. Bowel ObstructionBowel Obstruction
• Due to
-Intussusception, (diverticulum is the lead point)
-Mesodiverticular bands (connecting the
diverticulum to the mesentry and kinking of the
intestine or internal herniation)

91. Operative photo of a 4 years old child presented with intestinal
obstruction.Exploration revealed a mesodiverticular band which was divided
followed by wedge excision of the Meckel`s diverticulum with primary repair

92. Meckel’s Diverticulitis:Meckel’s Diverticulitis:
• Symptoms simulate acute appendicitis
• Result of luminal obstruction, bacterial
invasion, progressive inflammation
• Ectopic gastric mucosa predisposes
• 30% incidence of perforations
• Higher risk of peritonitis

93. TreatmentTreatment
1-Symptomatic Meckel`s requires either :
- Wedge excision with transverse repair
of the intestinal wall.
- Resection of the adjacent segment of
ilieum with end to end anastmosis.

94. 2-Incidentally found Meckel`s: (during
operation for another cause)
-If healthy wall,wide based and of short
length …..leave alone
-If narrow based ,long ….excise

95. 7-Anorectal Malformations7-Anorectal Malformations

96. SynonymsSynonyms
• imperforate anus
• anorectal malformations
• anorectal anomaly

97. FrequencyFrequency
• Anorectal malformations occur in approximately 1 per 5000
live births
 One of the most frequently encountered digestive tract
abnormality
 Frequency is slightly higher in males compared with females
 Associated anomaly: urogenital,another gastrointestinal anomaly,
cardiovascular, vertebra
 Arrest of the caudal descent of the urorectal septum toward the
cloacal membrane during the fourth week and ending by the
eighth week of gestation.

98. PC line: pubococcygeal line
I line: ischial line

99. TYPESTYPES
• HIGH TYPE
• LOW TYPE

100. Clinical Findings:Clinical Findings:
• Findings are associated with a high malformation
– A flat perineum, as evidenced by the lack of a midline gluteal
fold
– absence of an anal dimple, indicates that the patient has poor
muscles in the perineum.
• Perineal signs found in patients with low malformations
include
– the presence of meconium at the perineum,
– a bucket-handle malformation
– anal membrane (through which meconium is visible).

101. RADIOGRAPHY (INVERTOGRAM)RADIOGRAPHY (INVERTOGRAM)
16-24 hours16-24 hours

102. A flat perineumA flat perineum

103. A flat perineum-GIRLA flat perineum-GIRL

104. Perineal fistulaPerineal fistula

105. bucket-handle malformationbucket-handle malformation

106. Imperforate anus with rectovesical fistula

107. Imperforate anus with rectourethral fistula

108. Associated malformationsAssociated malformations
• The following associated anomalies can
occur separately or as VACTERL
associations:
– Esophageal atresia
– Duodenal atresia
– Ventricular or atrioseptal defects
– Tetrology of Fallot
– Hirschsprung's disease

109. Surgical Treatment:Surgical Treatment:
• Colostomy versus Definitive repair

110. COLOSTOMYCOLOSTOMY
)Sigmoid colostomy with distal mucous
fistula(

111. Definitive repairDefinitive repair
1-Anoplasty :
– Rectoperineal fistula
– Covered anus
– Bucket-handle malformation

112. • Posterior Sagittal Ano-Recto Plasty (PSARP)

113. 8-Intestinal Malrotation

114. a group of congenital anomalies resulting from
abnormal intestinal rotation and fixation

115.  Week 6~8: Herniation of midgut into the umbilical cord
with a 180 degree of counterclockwise rotation along the
axis of superior mesenteric artery
 Week 10: Return to the abdominal cavity with a final 90
degree of rotation to complete the 270-degree
counterclockwise rotation

116.  Nonrotation and Incomplete rotation: abnormal positioning of
the proximal small bowel and the cecum
 Duodenum compressed by abnormal peritoneal band(Ladd’s
band): high incomplete extrinsic obstruction
 Midgut volvulus: torsion of the narrow mesenteric pedicle
produces an acute closed-loop intestinal obstruction and
vascular strangulation.
 Proximal jejunum fused to the ascending colon by anomalous
peritoneal attachments

118. Newborn with:
 Emesis ： bilious, intermittent ， occur at 3-5 days after birth or
asymptomatic
 Abdominal distention: confined in epigastrium or diffuse to the full
abdomen in bowel necrosis
 Stool: normal meconium or bloody stool with volvulus and necrosis
Children and infant: asymptomatic since birth, intermittent or
sudden onset of intestinal obstruction

119.  1-Plain X-ray : double-bubble sign
 2-Barium meal follow through ： incomplete
duodenal obstruction; ligament of Treitz not to the left of
the midline; abnormal position of the proximal jejunal
loops to the right of the midline
 3-Barium enema: cecum in the upper or left abdomen

120. TreatmentTreatment
Principles:
-Asymptomatic malrotation
most recommend surgical treatment
some believe operation only necessary in young children
-High intestinal obstruction
operated on promptly, but not necessarily emergently
-Volulus with sign of bowel necrosis: immediate operation

121. Ladd′s operation )or Procedure(:
 Untwisting: Volvulus is always clockwise so the
small bowel must be rotated in a counterclockwise
fashion.
 Division of Ladd’s bands.
 Broadening of the base of the mesentry.
 Redistribution of small bowel to the right and colon
to the left of the abdominal cavity
 Appendictomy: to avoid misdiagnosis of
appendicitis later on.

122. Ladd′s Procedure

123.  O`neil textbook of pediatric surgery.
 Rob & Smith operative pediatric surgery.
 Shwartz principles of surgery.
 Kasr Al-Aini Introduction to surgery.

124. Thank You(mustafa_redwan@yahoo.com)