Dear Viewers,
Greetings from “ Surgical Educator”
Today I have uploaded a video on one of the congenital causes for obstructive jaundice- Biliary Atresia. In this episode, I am discussing about the etiology, types, clinical features, investigations, treatment and surgical outcome of Biliary Atresia. I hope you will enjoy the video. You can watch all my surgical teaching video casts in the following link: surgicaleducator.blogspot.com.
Intussusception is the most common acute abdominal disorder of early childhood. In this lecture, we describe the manifests of Intussusception, the diagnosis, and the treatment of this disease.
Dear Viewers,
Greetings from “ Surgical Educator”
Today I have uploaded a video on one of the congenital causes for obstructive jaundice- Biliary Atresia. In this episode, I am discussing about the etiology, types, clinical features, investigations, treatment and surgical outcome of Biliary Atresia. I hope you will enjoy the video. You can watch all my surgical teaching video casts in the following link: surgicaleducator.blogspot.com.
Intussusception is the most common acute abdominal disorder of early childhood. In this lecture, we describe the manifests of Intussusception, the diagnosis, and the treatment of this disease.
SHORT PRESENTATION ABOUT DIFFERENTIAL DIAGNOSIS ABOUT ACUTE LEFT LOWER QUADRANT PAIN , COMMON AND LESS COMMON CAUSES WITH CLUES TO DIAGNOSIS AND SOME EXAMPLES
HOPPING YOU LIKE IT
DR HISHAM ALKHATIB
CONSULTANT RADIOLOGIST
DIVERTICULAR DISEASE OF THE COLON
DEFINITION
They are acquired herniations of colonic mucosa through circular muscles at the points where blood vessels penetrate (points of least resistance).
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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3. Duodenal HematomaDuodenal Hematoma
• Causes:
• Blunt trauma
• RTA
• Associated injuries include
• ----laceration to the left lobe of liver and to the
pancreases
• Bleeding Disorders(Henoch-schonlein purpura)
• It can cause complete or partial obstruction
4. IMAGING
•Ba Meal
•( Thickened mucosal folds, localized filling defects
due to intramural hematoma)
•CT Abdomen
•(for assessment of acute trauma and hematoma
directly, or for abnormal duodenal enhancement)
5. Enhanced CTEnhanced CT
Intramural duodenal hematoma almost completelyIntramural duodenal hematoma almost completely
obscuring the lumenobscuring the lumen
6. DUPLICATION CYSTDUPLICATION CYST
• An abnormal portion of intestine which is attached
to or intrinsic with normal bowel
• Incomplete recanalization at around 8wks
• Any where in the GIT
• 1/3 involve distal small bowel
Types
• Tubular
• Spherical
• communication
7. • Presentation
depends on the size and site
• Esp. those assoc. with stomach or duodenum
present with
• Abd. Pain
• Vomiting
• May act as a lead point for Intussusception
• GI Bleeding ( From ectopic mucosa)
17. IMAGINGIMAGING
Radiography
•May be normal or localized dilated bowel loops
•5-10% radiodense appendicolith identified
Ultrasound
•Non compressible blind ending tubular structure
approx 6mm or more
•Increased echogenicity of mesenteric fat
•Hyperemia on color Doppler
•Free fluid / mesenteric lymph nodes
18. Right iliac fossa mixed echogenicity inflammatoryRight iliac fossa mixed echogenicity inflammatory
mass and echogenic focus with acousticmass and echogenic focus with acoustic
shadowingshadowing
19. Hypoechoic tubular structure 7mm in diameterHypoechoic tubular structure 7mm in diameter
adjacent to iliac vesselsadjacent to iliac vessels
23. HENOCH SCHONLEINHENOCH SCHONLEIN
PURPERAPURPERA
Small bowel vasculitis
•Jejunum most frequently involved
•Unknown etiology/postinfectious/post drug
therapy
Presentations with
•Purpuric rash over the buttocks & legs
•Abdominal pain
•glomerulonephritis
28. Polyps and polyposisPolyps and polyposis
syndromessyndromes
Isolated juvenile polyps
•Single or multiple
•Under 10 years of age
•Found in sigmoid colon and rectum
•Unlike adults they are hamartomas
•Present with painless rectal bleeding
leading to iron deficiency anemia
•Not premalignant
29. • Double contrast barium enema
• Endoscopy
• A pedunculated polyp with a long stalk is seen
30. Barium enema showing a pedunculated polyp in theBarium enema showing a pedunculated polyp in the
descending colondescending colon
31. Juvenile polyposisJuvenile polyposis
• Positive family hx (most cases)
• Five or more polyps
• Associated with higher long term risk of colonic
carcinoma
32. Peutz jeghers syndromePeutz jeghers syndrome
• Autosomal dominant
• Occur anywhere from stomach to rectum (mostly
small intestine)
• Associated with mucocutaneous pigmentation and
GI hamartomas
Small bowl follow through
• -multiple filling defects
35. • Familial polyposis coli
• Gardner syndrome
• Both are dominanly inherited
• Multiple adenomatous polyps are found (numerous
in colon)
• High malignant potential
• Prophylactic proctocolectomy usually
recommended
37. Small bowel malignanciesSmall bowel malignancies
Burkit type non Hodgkin lymphoma
•Mostly involve Ileocecal region
•Male predominance
•Peak incidence 5-8yrs
Presenting symptoms are
•Abdominal pain
•Palpable mass
•Failure to thrive
38. ULTRASOUND
•Thickened hypoechoic bowel loops are seen often
forming adherent masses with infiltration of adjacent
omentum & mesentery
•Hepatospenomegaly
•Retroperitoneal lymphadenopathy
39. CAUSES OF COLITIS INCAUSES OF COLITIS IN
CHILDHOODCHILDHOOD
• INFECTIOUS
• (compylobacter,E.coli,salmonella,shigella etc)
• INFLAMMATORY BOWEL DISEASE
• TYPHILITIS
• HEAMOLYTIC URAEMIC SYNDROME
• PSEUDOMEMBRANOUS COLITIS
• GRAFT VERSUS HOST REACTIONS
• ISCHAEMIC COLITS
• IRRADIATION COLITIS
40. CROHN’S DISEASECROHN’S DISEASE
• Involve any part of GIT from mouth to anus (usually
sparing the rectum)
• Prepubertal child or adolescent are effected
Extraintestinal features more prominent
• weight loss
• anorexia
• short stature
• Delayed puberty
45. Enema in crohn’s disease showing extensiveEnema in crohn’s disease showing extensive
cobblestoning due to linear ulceration &mucosalcobblestoning due to linear ulceration &mucosal
edema. Rectum is sparededema. Rectum is spared
46. ULCERATIVE COLITISULCERATIVE COLITIS
• Relapsing and remitting proctits
• Rectum is always effected
• Effects young adults(15-25yrs) with second smaller
peak at approx 60yrs
48. IMAGINGIMAGING
Double contrast barium enema
Proctosigmoidoscopy
•loss of normal mucosal vascular pattern (earliest
detectable change)
•ulceration is continuous & superficial
•(deep ulceration does occur)
•haustral blunting
49. • Luminal narrowing
• Colonic shortening(due to muscular abnormality
rather than fibrosis)
CT SCAN
not for primary diagnosis once toxic megacolon is
established
50. Double contrast barium enema shows granularDouble contrast barium enema shows granular
mucosa (changes of early disease)mucosa (changes of early disease)
54. HAEMOLYTIC URAEMICHAEMOLYTIC URAEMIC
SYNDROMESYNDROME
• Commonest cause of acute renal failure in children
• Diarrheal illness caused by E.coli leading to
• Microangiopathic anemia
• Thrombocytopenia and acute renal failure
56. INTUSSUSCEPTIONINTUSSUSCEPTION
• Invagination of a segment of bowel(the
intussusceptum) into the contiguous segment(the
intussuscipiens)
Site
• Ileocolic(approx 90% cases)
• Ileoileocolic,colocolic,ileoileal
Peak age incidence
• 6 months to 2yrs
57. Classic presentation
•Episodic abdominal pain
•Screaming episodes associated with passage of
blood & mucus(current jelly)
•Haemodynamic instability due to considerable fluid
shift
58. IMAGINGIMAGING
Abdominal radiograph
•Absence of bowel gas in the right iliac fossa with
rounded soft tissue mass
•A crescent of air at the apex of intussusception
•Or small bowl obstruction
Ultrasound(highly sensitive)
•a mass with multiple hyperechoic concentric rings
59. Paucity of bowel gas in the right iliac fossa andPaucity of bowel gas in the right iliac fossa and
soft tissue masssoft tissue mass
60. Transverse ultrasound showing multipleTransverse ultrasound showing multiple
hypoechoic concentric rings, central echogenichypoechoic concentric rings, central echogenic
mesentery and few small echogenic lymph nodesmesentery and few small echogenic lymph nodes
61. • Small crescents of peritoneal fluid may be trapped
b/w the layers of intussusception
• Colour flow with in the mass suggests bowel viability
• Small lymph nodes are frequently found within the
intussusception