This document provides an overview of numerical differentiation and integration methods. It discusses Newton's forward and backward difference formulas for computing derivatives, as well as Newton-Cote's formula, the trapezoidal rule, and Simpson's one-third and three-eighths rules for numerical integration. Examples of applying these methods to real-world problems are provided. The document also compares Simpson's one-third and three-eighths rules, noting their different assumptions about the polynomial order of the integrated function and requirements for the number of intervals.