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Legionella+Mycoplasma+Atypical Pneumonia

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Kamran Afzal, PhD.
Kamran Afzal, PhD.

The document discusses atypical pneumonia caused by Legionella, Mycoplasma, and Chlamydia. It notes that atypical pneumonia causes inflammation between alveoli rather than within them, appearing reticulonodular on imaging. Diagnosis involves culture, serology to detect antibodies or antigens, and PCR. Treatment is with macrolides or fluoroquinolones.

Health & MedicineTechnology
1 of 51
LEGIONELLA MYCOPLASMA ATYPICAL PNEUMONIA Dr Kamran Afzal Classified Microbiologist
LEGIONELLA
TAXONOMY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Legionella pneumophila ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
EPIDEMIOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HISTORICAL PERSPECTIVE ,[object Object],[object Object],[object Object]
HABITAT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
 
LEGIONNAIRES’ DISEASE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
LABORATORY DIAGNOSIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CULTURAL CHARACTERISTICS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
COLONY APPEARANCE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BIOCHEMICAL REACTIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TREATMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MYCOPLASMA
 
DISEASES
Differentiation of Species ,[object Object],[object Object],[object Object],[object Object]
MORPHOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
“ Fried Egg” Colonies of Mycoplasma M. pneumoniae colonies have a granular appearance
 
Can be part of normal flora ,[object Object]
Mycoplasma are cell wall deficient ,[object Object]
PATHOGENESIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
CLINICAL MANIFESTATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
LABORATORY DIAGNOSIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Culturing Mycoplasma ,[object Object],[object Object],[object Object],[object Object]
 
TREATMENT AND PREVENTION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ATYPICAL PNEUMONIA
DEFINITION ,[object Object],[object Object]
GROSS MANIFESTATIONS LOBAR PNEUMONIA BRONCHOPNEUMONIA INTERSTITIAL
ATYPICAL PNEUMONIA ,[object Object],[object Object],[object Object],[object Object]
 
Not prominent Prominent (myalgia, fatigue, N/V, diarrhea) Extra-pulmonary symptoms Purulent Scanty Sputum Productive cough Dry cough Cough Abrupt Gradual Onset S. pneumoniae , H. influenzae , K. pneumoniae , mixed aerobic and anaerobic oral flora M. pneumoniae , L. pneumophilia, C. pneumophilla, viruses, protozoa and fungi Etiology TYPICAL PNEUMONIA ATYPICAL PNEUMONIA
ROUTES OF INFECTION ,[object Object],[object Object],[object Object],[object Object],[object Object]
INVESTIGATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Serology ,[object Object],[object Object]
Specific Serological Tests ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Histopathology ,[object Object],[object Object]
[object Object],[object Object],Radiology
COMPLICATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Legionella+Mycoplasma+Atypical Pneumonia