This document discusses several types of molecular recombination: homologous recombination, site-specific recombination, and transposition. It describes reciprocal homologous recombination through the double-strand break model and nonreciprocal homologous recombination through the Fox model. Site-specific recombination is important for viral genome insertion and has small regions of homology. Transposition involves transposable elements like transposons that are mobile genetic elements.
BACTERIAL RECOMBINATION, PLASMIDS AND EPISOMESsushma93
Genetic recombination - transfer of DNA from one organism (donor) to another organism (recipient). The transferred donor DNA may then be integrated into the recipient's genetic material by various mechanisms
Bacterial recombination occurs in three ways
Transformation
Transduction
Conjugation
BACTERIAL RECOMBINATION, PLASMIDS AND EPISOMESsushma93
Genetic recombination - transfer of DNA from one organism (donor) to another organism (recipient). The transferred donor DNA may then be integrated into the recipient's genetic material by various mechanisms
Bacterial recombination occurs in three ways
Transformation
Transduction
Conjugation
the horizontal gene transfer in bacteria is not only important for survival but has its evolutionary significance too. this presentation is a prelude to the three classical types of HGT in bacteria
binary fisson, conjugation, transposons, transduction, transformation, plasmids, insertion sequences, dissemination of drug resistance in bacteria, genetic transfer in bacteria, theta replication, rolling circle replication
this presentation is about reproduction of bacteria also known as genetic recombination. it consist of three types i.e. transformation, transduction and conjugation.
the horizontal gene transfer in bacteria is not only important for survival but has its evolutionary significance too. this presentation is a prelude to the three classical types of HGT in bacteria
binary fisson, conjugation, transposons, transduction, transformation, plasmids, insertion sequences, dissemination of drug resistance in bacteria, genetic transfer in bacteria, theta replication, rolling circle replication
this presentation is about reproduction of bacteria also known as genetic recombination. it consist of three types i.e. transformation, transduction and conjugation.
Genetic Screening and Prenatal Diagnosis of Thalassemias and Hemoglobinopathies in Taiwan Today by Ching-Tien Peng, MD, MPH, Superintendent & Prof. of The Children’s Hospital, China Medical University & Hospitals, Prof. of Biotechnology, Asia University, Taichung, Taiwan
Prenatal Testing, deteksi kelainan bawaan sejak dalam kandunganHendrik Sutopo
Pengenalan mengenai prenatal diagnosis.
Memberikan gambaran sekilas mengenai cara-cara untuk mengetahui kelainan bawaan sejak janin dalam kandungan.
lebih ditujukan untuk kalangan medis.
Non Invasive Prenatal Testing (NIPT)
Accelerate your Kubernetes clusters with Varnish CachingThijs Feryn
A presentation about the usage and availability of Varnish on Kubernetes. This talk explores the capabilities of Varnish caching and shows how to use the Varnish Helm chart to deploy it to Kubernetes.
This presentation was delivered at K8SUG Singapore. See https://feryn.eu/presentations/accelerate-your-kubernetes-clusters-with-varnish-caching-k8sug-singapore-28-2024 for more details.
Elevating Tactical DDD Patterns Through Object CalisthenicsDorra BARTAGUIZ
After immersing yourself in the blue book and its red counterpart, attending DDD-focused conferences, and applying tactical patterns, you're left with a crucial question: How do I ensure my design is effective? Tactical patterns within Domain-Driven Design (DDD) serve as guiding principles for creating clear and manageable domain models. However, achieving success with these patterns requires additional guidance. Interestingly, we've observed that a set of constraints initially designed for training purposes remarkably aligns with effective pattern implementation, offering a more ‘mechanical’ approach. Let's explore together how Object Calisthenics can elevate the design of your tactical DDD patterns, offering concrete help for those venturing into DDD for the first time!
Connector Corner: Automate dynamic content and events by pushing a buttonDianaGray10
Here is something new! In our next Connector Corner webinar, we will demonstrate how you can use a single workflow to:
Create a campaign using Mailchimp with merge tags/fields
Send an interactive Slack channel message (using buttons)
Have the message received by managers and peers along with a test email for review
But there’s more:
In a second workflow supporting the same use case, you’ll see:
Your campaign sent to target colleagues for approval
If the “Approve” button is clicked, a Jira/Zendesk ticket is created for the marketing design team
But—if the “Reject” button is pushed, colleagues will be alerted via Slack message
Join us to learn more about this new, human-in-the-loop capability, brought to you by Integration Service connectors.
And...
Speakers:
Akshay Agnihotri, Product Manager
Charlie Greenberg, Host
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
UiPath Test Automation using UiPath Test Suite series, part 4DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 4. In this session, we will cover Test Manager overview along with SAP heatmap.
The UiPath Test Manager overview with SAP heatmap webinar offers a concise yet comprehensive exploration of the role of a Test Manager within SAP environments, coupled with the utilization of heatmaps for effective testing strategies.
Participants will gain insights into the responsibilities, challenges, and best practices associated with test management in SAP projects. Additionally, the webinar delves into the significance of heatmaps as a visual aid for identifying testing priorities, areas of risk, and resource allocation within SAP landscapes. Through this session, attendees can expect to enhance their understanding of test management principles while learning practical approaches to optimize testing processes in SAP environments using heatmap visualization techniques
What will you get from this session?
1. Insights into SAP testing best practices
2. Heatmap utilization for testing
3. Optimization of testing processes
4. Demo
Topics covered:
Execution from the test manager
Orchestrator execution result
Defect reporting
SAP heatmap example with demo
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
Essentials of Automations: Optimizing FME Workflows with ParametersSafe Software
Are you looking to streamline your workflows and boost your projects’ efficiency? Do you find yourself searching for ways to add flexibility and control over your FME workflows? If so, you’re in the right place.
Join us for an insightful dive into the world of FME parameters, a critical element in optimizing workflow efficiency. This webinar marks the beginning of our three-part “Essentials of Automation” series. This first webinar is designed to equip you with the knowledge and skills to utilize parameters effectively: enhancing the flexibility, maintainability, and user control of your FME projects.
Here’s what you’ll gain:
- Essentials of FME Parameters: Understand the pivotal role of parameters, including Reader/Writer, Transformer, User, and FME Flow categories. Discover how they are the key to unlocking automation and optimization within your workflows.
- Practical Applications in FME Form: Delve into key user parameter types including choice, connections, and file URLs. Allow users to control how a workflow runs, making your workflows more reusable. Learn to import values and deliver the best user experience for your workflows while enhancing accuracy.
- Optimization Strategies in FME Flow: Explore the creation and strategic deployment of parameters in FME Flow, including the use of deployment and geometry parameters, to maximize workflow efficiency.
- Pro Tips for Success: Gain insights on parameterizing connections and leveraging new features like Conditional Visibility for clarity and simplicity.
We’ll wrap up with a glimpse into future webinars, followed by a Q&A session to address your specific questions surrounding this topic.
Don’t miss this opportunity to elevate your FME expertise and drive your projects to new heights of efficiency.
Dev Dives: Train smarter, not harder – active learning and UiPath LLMs for do...UiPathCommunity
💥 Speed, accuracy, and scaling – discover the superpowers of GenAI in action with UiPath Document Understanding and Communications Mining™:
See how to accelerate model training and optimize model performance with active learning
Learn about the latest enhancements to out-of-the-box document processing – with little to no training required
Get an exclusive demo of the new family of UiPath LLMs – GenAI models specialized for processing different types of documents and messages
This is a hands-on session specifically designed for automation developers and AI enthusiasts seeking to enhance their knowledge in leveraging the latest intelligent document processing capabilities offered by UiPath.
Speakers:
👨🏫 Andras Palfi, Senior Product Manager, UiPath
👩🏫 Lenka Dulovicova, Product Program Manager, UiPath
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
UiPath Test Automation using UiPath Test Suite series, part 3DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 3. In this session, we will cover desktop automation along with UI automation.
Topics covered:
UI automation Introduction,
UI automation Sample
Desktop automation flow
Pradeep Chinnala, Senior Consultant Automation Developer @WonderBotz and UiPath MVP
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
The Art of the Pitch: WordPress Relationships and SalesLaura Byrne
Clients don’t know what they don’t know. What web solutions are right for them? How does WordPress come into the picture? How do you make sure you understand scope and timeline? What do you do if sometime changes?
All these questions and more will be explored as we talk about matching clients’ needs with what your agency offers without pulling teeth or pulling your hair out. Practical tips, and strategies for successful relationship building that leads to closing the deal.
3. Nonreciprocal Homologous Recombination: Fox Model
• incorporation of single
strand of DNA into
chromosome, forming
heteroduplex DNA
• thought to occur during
bacterial transformation
4. Site-specific recombination
• important in insertion of viral genomes into
host chromosomes
• there is only a small region of homology
between inserted genetic material & host
chromosome
5. transposition & transposable elements
transposable elements = transposons =
mobile genetic elements = “jumping genes”
6. Please note that due to differing
operating systems, some animations
will not appear until the presentation is
viewed in Presentation Mode (Slide
Show view). You may see blank slides
in the “Normal” or “Slide Sorter” views.
All animations will appear after viewing
in Presentation Mode and playing each
animation. Most animations will require
the latest version of the Flash
Player, which is available at
http://get.adobe.com/flashplayer.
7.
8.
9. Please note that due to differing
operating systems, some animations
will not appear until the presentation is
viewed in Presentation Mode (Slide
Show view). You may see blank slides
in the “Normal” or “Slide Sorter” views.
All animations will appear after viewing
in Presentation Mode and playing each
animation. Most animations will require
the latest version of the Flash
Player, which is available at
http://get.adobe.com/flashplayer.
12. Please note that due to differing
operating systems, some animations
will not appear until the presentation is
viewed in Presentation Mode (Slide
Show view). You may see blank slides
in the “Normal” or “Slide Sorter” views.
All animations will appear after viewing
in Presentation Mode and playing each
animation. Most animations will require
the latest version of the Flash
Player, which is available at
http://get.adobe.com/flashplayer.
16. Bacterial Conjugation
• Transfer of genes
between bacteria
that depends on
– direct cell to cell
contact mediated by
a sex pilus
– type IV secretion
system
20. +
-
F x F Mating
– copy of F factor is transferred to recipient &
does not integrate into the host chromosome
– donor genes usually not transferred
23. Please note that due to differing
operating systems, some animations
will not appear until the presentation is
viewed in Presentation Mode (Slide
Show view). You may see blank slides
in the “Normal” or “Slide Sorter” views.
All animations will appear after viewing
in Presentation Mode and playing each
animation. Most animations will require
the latest version of the Flash
Player, which is available at
http://get.adobe.com/flashplayer.
24. Hfr Conjugation
– donor has F factor integrated into its
chromosome (Hfr cell)
– donor genes are transferred to recipient cell
– complete copy of the F factor is usually not
transferred
28. F’ Conjugation
• F factor incorrectly leaves host chromosome
• some of the F factor is left behind in host
chromosome
• some host genes have been removed along
w/ some of the F factor
– these genes can be transferred to a second host
cell by conjugation
30. Bacterial Transformation
• uptake of naked DNA by a competent cell
followed by incorporation of the DNA into
the recipient cell’s genome
31.
32.
33.
34. Transduction
• transfer of bacterial genes by viruses
• viruses (bacteriophages) can carry out the
lytic cycle in which the host cell is
destroyed or the viral DNA can integrate
into the host genome, becoming a latent
prophage
35.
36. Generalized Transduction
• any part of bacterial genome can be
transferred
• occurs during lytic cycle
• during assembly, fragments of host DNA
mistakenly packaged into phage head
– generalized transducing particle
38. Specialized Transduction
• a.k.a. restricted transduction
• carried out only by lysogenic/temperate
phages
• only specific portion of bacterial genome is
transferred
• occurs when prophage incorrectly excises
