The excretory system of insects involves several organs that work together to remove nitrogenous waste from the body. The main excretory organs are the Malpighian tubules, which produce a filtrate that selectively reabsorbs water and ions while eliminating waste. For terrestrial insects, the main waste product is uric acid, while aquatic insects excrete ammonia. The filtrate produced by the Malpighian tubules passes to the gut where further modification occurs before excretion, helping to maintain fluid and ion balance in the insect's body.
its all about respiratory system of insects, arrangement and position of spiracles system. Types of different respiratory systems in aquatic insects.
Contact Email: mzeeshan_93@yahoo.com
its all about respiratory system of insects, arrangement and position of spiracles system. Types of different respiratory systems in aquatic insects.
Contact Email: mzeeshan_93@yahoo.com
Excretory system
Fuction of excretory system
Excretory organ
1>Malpighian tubules
2>Nephrocyte
3>Oenocytes
5>Integument
6>rectum
→Urine production
Formation of primary urine
Movement of solute
Excreation of ions
Modification of primary urine
Salt and water balance
terrestial insects
Fresh water insect
Salt water insect
Nitrogen Excretion
There needs to be a balance between water ingested and water eliminated.
In order to maintain homeostatic levels of water, the body must undergo osmoregulation.
osmoregulation in invertebrates- it is a processes by which any organisms maintains the fluid and salt balance of its body, which is important for proper functioning of organs .
Osmoregulation Mechanisms and Adaptations in Various Organisms.pdfNAGENDRA SINGH
Osmoregulation is the process by which living organisms regulate the concentration of water and solutes (such as salts) in their bodies to maintain homeostasis, or a stable internal environment. This is especially important in aquatic organisms, which are surrounded by water of varying salt concentrations, but also in terrestrial organisms that need to conserve water.
In animals, osmoregulation involves a variety of physiological processes such as filtration, reabsorption, and secretion by the kidneys. Fish, for example, have specialized organs called gills that are adapted to exchange water and solutes with their environment. They also have kidneys that regulate the concentration of ions in their bodies. Other animals, such as birds, excrete waste products in the form of uric acid, which conserves water.
Plants also engage in osmoregulation, using a process called osmosis to absorb water and nutrients from the soil. They also use various mechanisms, such as opening and closing stomata, to control water loss through transpiration.
Overall, osmoregulation is an essential process for maintaining the internal environment of living organisms and ensuring their survival.
Sure, here are some additional details about osmoregulation:Types of Osmoregulation: There are two types of osmoregulation, depending on the organism's environment. In freshwater environments, organisms have to regulate the inflow of water and outflow of salts. In contrast, marine organisms have to regulate the outflow of water and inflow of salts.
Osmoregulatory Organs: Different organisms have evolved various osmoregulatory organs to maintain the balance of water and solutes in their bodies. For example, insects have Malpighian tubules, which remove waste and excess water from the body. Terrestrial animals such as reptiles, birds, and mammals have kidneys that filter blood and excrete waste products in the form of urine.
Osmolarity: Osmoregulation maintains the balance of osmolarity in the body, which is the concentration of solutes in a solution. Osmolarity is measured in units of osmoles per liter (osmol/L) and is important for the regulation of water balance in organisms.
Regulation of Salt Balance: In addition to regulating water balance, osmoregulation also involves the regulation of salt balance. Salt balance is critical for cellular functions such as enzyme activity, nerve function, and muscle contraction.
Osmoregulation and Adaptation: Different organisms have evolved various mechanisms for osmoregulation to adapt to their environment. For example, some desert animals conserve water by producing dry feces or uric acid instead of urea, which conserves water. Some marine organisms, such as sharks, have a high concentration of urea in their blood, which helps them retain water in the ocean's salty environment.
Osmoregulation and Human Health: Osmoregulation is essential for human health, and disruptions in the body's water and salt balance can lead to health problems such a
Excretion in various invertebrates and vertebrates is dealt as per the PG syllabus prescribed by Vijayanagara Sri Krishnadevaraya University Ballari. It is useful for the PG students studying animal physiology as the core subject under zoology. It gives a overall picture of excretion to the teacher who is teaching animal physiology to the collegiate and university levels.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
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Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
2. Excretory system
The removal of waste
products of metabolism,
especially nitrogenous
compounds from the
body of insects is known
as excretion.
The excretion process
helps the insect to
maintain salt water
balance and thereby
physiological
homeostasis.
3. Excretory organs
1. Malpighian tubules
Thin, blind-ending tubules, originating near the
junction of mid and hindgut, externally covered by
peritoneal coat and supplied with muscle fibres and
tracheoles
predominantly involved in regulation of salt, water
and nitrogenous waste excretion.
This structure was discovered by Marcello Malpighi.
4. Excretory organs
2. Nephrocytes: Cells that sieve the haemolmph
for products that they metabolize (pericardial
cells).
3. Fat bodies: A loose or compact aggregation of
cells, mostly trophocytes, suspended in the
haemocoel, responsible for storage and
excretion.
4. Oenocytes: These are specialised cells of
haemocoel, epidermis or fat body with many
functions. One is excretion.
5. Integument: The outer covering of the living
tissues of an insect.
6.Tracheal system: The insect gas exchange
system, comprising tracheae and tracheoles.
5. Nitrogen excretion
Terrestrial insects excrete waste products as uric acid or
certain of its salts called urates, which were water
insoluble and requires less amount of water for waste
product removal. This type of excretion is known as
uricotelism.
In aquatic insects ammonia is the excretory product,
which is freely soluble in water and requires more
amount of water for waste product removal. This type of
excretion is known as ammonotelism.
6. Cryptonephry
The distal ends of the Malpighian
tubules are held in contact with
the rectal wall by the perinephric
membrane,
which is concerned either with
efficient dehydration of faeces
before their elimination or ionic
regulation.
(e.g. Adult Coleptera, larval
Lepidoptera and larval symphyta)
7. Physiology
The malpighian tubules produce a filtrate (the
primary urine) which is isosmotic but ionically
dissimilar to the haemolymph and selectively
reabsorbs water and certain solutes, but
eliminates others.
The malpighian tubules produces an isosmotic
filtrate which is high in K+ and low in Na+with
Cl- as major anion.
The active transport of ions especially K+ into
the tubule lumen generates an osmotic pressure
gradiant for the passive flow of water.
8. Sugars and most amino acids are also passively
filtered from the haemolymph via junctions between
the tubule cells, where as amino acids and non-
metabolizables and toxic organic compounds are
actively transported into the tubule lumen.
Sugars are reabsorbed from the lumen and returned
to the haemolymph.
The continuous secretory activity of each Malpighian
tubule leads to a flow of primary urine from its
lumen towards and into the gut.
In the rectum, the urine is modified by removal of
solutes and water to maintain fluid and ionic
homeostasis of the body
Physiology
9. Storage Excretion
The excretory waste materials are
retained within the body in different
sites.
Uric acid is stored as urates in the cells
of fat body e.g., American cockroach.
Uric acid is stored in the body wall,
giving white colour, e.g., Red cotton
bug.
Uric acid is stored in the male accessory
glands to produce the outer coat of
spermatophore, which is excreted
during copulation.
Uric acid is stored in the wing scales
giving white colour. e.g., Pierid
butterflies.
Waste products of pupal metabolism
