This document discusses Haemophilus influenzae, a gram-negative coccobacillary bacteria. It was first isolated in 1892 and thought to cause influenza. There are two main types: unencapsulated and encapsulated strains. Encapsulated type b strains cause more invasive diseases like meningitis while unencapsulated commonly cause localized infections. The document outlines the virulence factors, pathogenesis, clinical manifestations, diagnosis and prevention of H. influenzae infections. It also briefly discusses the HACEK group of bacteria which can cause endocarditis.