Ketone bodies are produced when there is an imbalance between lipid and carbohydrate metabolism. This can occur during prolonged fasting, very low carbohydrate diets, or diabetic conditions where glucose cannot be processed. The liver produces ketone bodies from acetyl-CoA to balance excess fatty acid breakdown. The three ketone bodies are acetoacetate, beta-hydroxybutyrate, and acetone. Ketone bodies accumulate in the blood and are excreted in urine, potentially causing ketoacidosis with associated symptoms like headache, dry mouth, and foul breath. Severe ketoacidosis can lead to coma and death if not addressed.