The document discusses various electrochemical methods of analysis in pharmaceutical chemistry, focusing on conductometry and its applications. It details the principles of conductometric titration, instrumentation, and various types of titrations, including acid-base and redox titrations. Key concepts such as conductivity, electrolites, and cell types are also explained.

1. Electrochemical Methods of analysis
Presented By,
Prof.Vedanshu R.Malviya
M.Pharm (Pharmaceutics)
P. R.Pote Patil College of Pharmacy,
Amravati.

2. Pharmaceutical Analysis
• It is divided into four types
• Electrochemical method
• Types of electrochemical methods
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3. conductometry
• What is conductivity
• What is conductometry
• Conductometry and Titration
• Conductive Solution
• Strong Electrlytes
• Weak Electrolytes
3

4. Some imp terms
• Ohms Law
• Conductance
• Specific resistance
• Specific conductance
• Equivalent conductivity
• Molecular conductance:
• Effect of dilution
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5. Instrumentation
• Conductivity cell
• Conductometer
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6. Conductivity cell
• Made of pyrex or quartz and are fitted with two
platinum electrodes.
• Should be placed in vessel containing water to maintain
constant temperature.
• Determination of cell constant
• Types:
• 1. Type-A – Low Conductance Measurement Cell
• 2. Type-B- Conductivity cell for PPT type of cell
• 3. Type-C- Dip Cell type
• Electrodes
• Conductivity Water6

7. Principal of Conductometric Titration
• Reaction between anions and cations
• It is either increase or decrease
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8. Types of Conductometric Titration
• The determination of end point of a
titration by means of conductivity
measurements are known as
conductometric titrations.
 Acid-base titration
 Precipitation titration
 Replacement titration
 Redox (oxidation-reduction) titration
 Complexometric titration
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9. Acid-base titration
• SA Vs SB
• SA Vs WB
• WA Vs SB
• WA Vs WB
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10. Precipitation Titration
• [K++Cl-]+[Ag++No3
_]
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11. Redox Titration
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0
50
100
150
200
250
300
350
400
0 10 20 30 40 50 60
6 Fe2++Cr2O7
2-+14H+→6Fe3++2Cr3++7H2O

12. applications
• Determination of solubility of sparingly soluble material
• Kinetic studies
• Degree of dissociation of weaker electrolytes
• Basicity of organic acids
• Determination of concentration
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