This document discusses the differences between pedagogical and andragogical assumptions and design factors for teaching based on Knowles' principles of andragogy. Some key differences covered include pedagogy being subject-centered and teacher-directed while andragogy is problem-centered and involves mutual planning between teacher and learner. Andragogical design factors emphasize the learner's experience, self-directedness, and readiness to learn based on life roles rather than biological development alone. Examples are requested of how andragogical principles can be applied in medical and health professions education.