Carbon Dioxide Transport

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Transport of carbon dioxide H + ,[object Object],[object Object],[object Object],[object Object]

Transport of carbon dioxide ,[object Object]

Transport of carbon dioxide ,[object Object],CO 2 plasma

Transport of carbon dioxide ,[object Object],+ H 2 O H + + HCO 3 - plasma CO 2 enzyme

Transport of carbon dioxide ,[object Object],HCO 3 - plasma

Transport of carbon dioxide ,[object Object],CO 2 + H 2 O H + + HCO 3 - plasma enzyme

Formation of hydrogen carbonate ,[object Object],[object Object],[object Object]

Formation of hydrogen carbonate ,[object Object],[object Object],[object Object],[object Object]

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Neural control of respiration (like neural control of many other physiological functions, micturition, for example) is highly complex and not fully elucidated. Research is still going on to determine the centers in the brain and their complex interactions. There may be variations of opinion between different researchers depending on newer findings. Every effort has been made to keep this information as current and authoritative as possible, yet in a simple enough form for the student to understand and digest the information. Dr Sanjoy Sanyal, Professor and Course Director of Neuroscience and FCM-III Neurology in Caribbean created this PPTX after studying this complex topic for a very long time. Tags: Respiration, Breathing, Respiratory Centers, Brainstem, Apneustic Breathing, Biots Breathing, Cheyne-Stokes, Ataxic, Agonal, Kussmaul, Brainstem Reticular Nuclei, NTS, Locus Ceruleus, Fastigial, Raphe nucleus, Vagus, RTN nucleus, pFRG nucleus, Kolliker-Fuse, PBC nucleus, RVL nucleus "Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use." Educational Value: A very complex and poorly understood topic has been rendered in as simple a format and style as possible, so as to make it easily digestible to any Basic Science medical student and Medical Resident

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The control of respiration seems to be based on the following factors: a) An intrinsic rhythm of the respiratory neurones of the medulla oblongata. This rhythm is dependent upon oxygen supply to the neurones involved. It is regulated by both reflex and chemical mechanisms. b) The chemical regulation of respiration concerns the hydrogen ion content of the respiratory neurones which in turn is dependent upon the carbon dioxide tension of the blood and the rate of flow of blood through the medulla. Variations in blood oxygen tension under normal conditions are not thought to be concerned with direct regulating effects on the respiratory neurones. The control of respiration seems to be based on the following factors: a) An intrinsic rhythm of the respiratory neurones of the medulla oblongata. This rhythm is dependent upon oxygen supply to the neurones involved. It is regulated by both reflex and chemical mechanisms. b) The chemical regulation of respiration concerns the hydrogen ion content of the respiratory neurones which in turn is dependent upon the carbon dioxide tension of the blood and the rate of flow of blood through the medulla. Variations in blood oxygen tension under normal conditions are not thought to be concerned with direct regulating effects on the respiratory neurones. The Chemical Control of Respiration As already pointed out the role of anoxemia is concerned with a direct depressing influence of oxygen lack on the respiratory cells of the medulla, and an opposing excitatory effect upon chemoreceptors in the carotid body whose stimulation results in reflex augmentation of respiration. The respiratory neurones of the medulla, however, are extremely sensitive to variations in the CO2 tension of the blood and somewhat less so to any other acids. In both cases the stimulatory effect concerns

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At the end of this session, the student should be able to: Describe the forms in which carbon dioxide is transported in the blood. Describe the importance of the chloride shift in the transport of carbon dioxide by blood and the changes caused by this shift. Describe carbon dioxide dissociation curves and how it is affected by oxygen binding to hemoglobin. Discuss respiratory acidosis and alkalosis, and their compensatory role (revise). Define respiratory exchange ratio and mention the significance of its estimation. GUYTON & HALL Textbook of Medical Physiology, 12th edition, page: 502-504.

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