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Nerve Impulses (pg 6)
Nerve Impulses (pg 6)
• All functions associated with the nervous
  system are based on two characteristics of
  neurons: excitability and conductivity
Nerve Impulses (pg 6)
• All functions associated with the nervous
  system are based on two characteristics of
  neurons: excitability and conductivity
• Excitability: Ability to respond to a stimulus.
  Neurons respond to stimuli by generating
  action potentials
Nerve Impulses (pg 6)
• All functions associated with the nervous
  system are based on two characteristics of
  neurons: excitability and conductivity
• Excitability: Ability to respond to a stimulus.
  Neurons respond to stimuli by generating
  action potentials
• Conductivity: ability to transmit an impulse
  from one point to another
Generation of an Action Potential
Generation of an Action Potential
1. Resting: Neuron cell membrane is
  impermeable to Na+ and K+. High
  concentration of Na+ outside cell and K+ inside
  cell. Also lots of negative ions inside cell, so it
  has a negative charge (-70 mv)
2. Depolarization: Stimulus causes Na+ channels
  in the membrane to open. Na+ rushes into the
  cell, driven by concentration gradient and the
  negative charge inside the cell. Results in
  depolarization (0 mv)
3. Reverse polarization: So much Na+ rushes into
  the cell that the polarity of the membrane
  becomes reversed (positive on the inside,
  negative on the outside). +30 mv
4. Repolarization: Na+ channels close, so no
  more Na+ gets into the cell. K+ channels open
  and K+ rushes out of the cell, driven by the
  concentration gradient. Cells becomes
  negative on the inside (-70 mv)
Conduction along a neuron
• Once an action potential has been generated,
  it must be propagated along the length of the
  neuron
Conduction along a neuron
• Once an action potential has been generated,
  it must be propagated along the length of the
  neuron
• The reverse polarity at one point of the
  neuron acts as a stimulus to the next point on
  the neuron, causing it to go through an action
  potential
Conduction along a neuron
• Once an action potential has been generated, it
  must be propagated along the length of the
  neuron
• The reverse polarity at one point of the neuron
  acts as a stimulus to the next point on the
  neuron, causing it to go through an action
  potential
• In unmyelinated axons this process is continuous,
  in myelinated fibers, the impulse jumps from
  node to node
Conduction across a Synapse
• Synapse = Region of communication between
  two neurons
Conduction across a Synapse
• Synapse = Region of communication between
  two neurons
• Neurons are separated by a space called the
  synaptic cleft. When a nerve impulse reaches
  the end of an axon it causes neurotransmitter
  molecules to be released into the cleft. The
  neurotransmitters diffuse over to the other
  neuron, where they cause an action potential

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Nerve impulses 2012

  • 2. Nerve Impulses (pg 6) • All functions associated with the nervous system are based on two characteristics of neurons: excitability and conductivity
  • 3. Nerve Impulses (pg 6) • All functions associated with the nervous system are based on two characteristics of neurons: excitability and conductivity • Excitability: Ability to respond to a stimulus. Neurons respond to stimuli by generating action potentials
  • 4. Nerve Impulses (pg 6) • All functions associated with the nervous system are based on two characteristics of neurons: excitability and conductivity • Excitability: Ability to respond to a stimulus. Neurons respond to stimuli by generating action potentials • Conductivity: ability to transmit an impulse from one point to another
  • 5. Generation of an Action Potential
  • 6. Generation of an Action Potential 1. Resting: Neuron cell membrane is impermeable to Na+ and K+. High concentration of Na+ outside cell and K+ inside cell. Also lots of negative ions inside cell, so it has a negative charge (-70 mv)
  • 7. 2. Depolarization: Stimulus causes Na+ channels in the membrane to open. Na+ rushes into the cell, driven by concentration gradient and the negative charge inside the cell. Results in depolarization (0 mv)
  • 8. 3. Reverse polarization: So much Na+ rushes into the cell that the polarity of the membrane becomes reversed (positive on the inside, negative on the outside). +30 mv
  • 9. 4. Repolarization: Na+ channels close, so no more Na+ gets into the cell. K+ channels open and K+ rushes out of the cell, driven by the concentration gradient. Cells becomes negative on the inside (-70 mv)
  • 10. Conduction along a neuron • Once an action potential has been generated, it must be propagated along the length of the neuron
  • 11. Conduction along a neuron • Once an action potential has been generated, it must be propagated along the length of the neuron • The reverse polarity at one point of the neuron acts as a stimulus to the next point on the neuron, causing it to go through an action potential
  • 12. Conduction along a neuron • Once an action potential has been generated, it must be propagated along the length of the neuron • The reverse polarity at one point of the neuron acts as a stimulus to the next point on the neuron, causing it to go through an action potential • In unmyelinated axons this process is continuous, in myelinated fibers, the impulse jumps from node to node
  • 13. Conduction across a Synapse • Synapse = Region of communication between two neurons
  • 14. Conduction across a Synapse • Synapse = Region of communication between two neurons • Neurons are separated by a space called the synaptic cleft. When a nerve impulse reaches the end of an axon it causes neurotransmitter molecules to be released into the cleft. The neurotransmitters diffuse over to the other neuron, where they cause an action potential