Industrial Fermenters

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Industrial fermenters are used to grow cells on a large scale by carefully controlling the environment. They are made of stainless steel and can hold up to 200,000 liters. Nutrients are fed in through sterile pipes and conditions like temperature, pH, oxygen, and carbon dioxide levels are monitored electronically and automatically regulated. Fermenters require sterile conditions and cooling to control cell growth and regulate temperature increases from microbial activity that could kill the cells. Most fermentations are batch processes but some use continuous culture systems with steady nutrient input and waste removal.

Industrial fermenters Growing cells on a large scale

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Industrial fermenters Control panel for an industrial fermentation operation

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Introduction : Antibiotics are antimicrobial agents produced naturally by other microbes (usually fungi or bacteria) The first antibiotic was discovered in 1896 by Ernest Duchesne and in 1928 "rediscovered" by Alexander Fleming from the filamentous fungus Penicilium notatum. The antibiotic substance, named penicillin, was not purified until the 1940s (by Florey and Chain), just in time to be used at the end of the second world war. Penicillin was the first important commercial product produced by an aerobic, submerged fermentation

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