This document discusses anisocoria, or unequal pupil size between the two eyes. It begins by defining anisocoria and outlining the normal sympathetic and parasympathetic pathways that control pupil size. It then distinguishes between physiological anisocoria, which can occur normally, and pathological anisocoria, which can be due to local factors affecting just one eye or defects in the sympathetic or parasympathetic nervous systems controlling both eyes. The document concludes by listing questions doctors should consider when examining a patient with anisocoria.