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Chapter One Introduction to Pathology Section A What is pathology?
Definition of Disease  ,[object Object]
Classification of Diseases: ,[object Object],[object Object],[object Object],[object Object]
Pathology ,[object Object],[object Object],[object Object]
Study of Disease: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Pathology
Pathology focuses on 4 aspects of disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Etiology: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Multifactorial:
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Pathogenesis: ,[object Object],[object Object]
Pathogenesis ,[object Object],[object Object]
Pathogenesis Immunologic, cytogenetic and molecular analyses of  tissues and cells are increasingly becoming guides to render diagnoses, to assess prognosis, and to suggest therapy.
[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],MORPHOLOGY Morphology remains at the heart of diagnostic pathology.
Morphology: ,[object Object]
Renal Infarction
 
 
Normal glomerulus
Membranous GN
Clinical Significance: ,[object Object],[object Object]
Pathology Summary: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Section B What do pathologists do?
[object Object],[object Object],Scope  of Pathology
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
 
 
 
 
 
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Tissue sections are  embedded with paraffin.
stony hard lump or mass on palpation
 
Diagnosis:  Carcinoma of the breast The invasive duct carcinoma usually has an abundant fibrous stroma, so it is also refered to as scirrhous carcinoma. Dense collagenous background
[object Object],[object Object],[object Object]
Sputum smears of  cytology
Pap smear of CIN-III Large hyperchromatic nuclei, nuclear pleomorphism .There are  some interspersed neutrophils with lobated nuclei and much smaller size.
Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Sample Case:
Clinical Details: ,[object Object],[object Object],[object Object],[object Object],[object Object]
Right neck mass
Lymphnode Biopsy ,[object Object],[object Object]
Lymphnode Biopsy ,[object Object],[object Object]
Histiocytic/Tcell NHL ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],In vitro:   Tissue culture Organ culture Cell culture In vivo:   Experimental animals Nude mice
[object Object],[object Object]
[object Object],[object Object]
 
Nude mice
Section C How do pathologists do?
RESEARCH METHODS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
Renal Infarction
 
 
 
 
[object Object],[object Object],[object Object]
Renal Infarction
Liver cirrohsis
Liver carcinoma
[object Object],[object Object],[object Object]
 
 
[object Object],[object Object]
Normal glomerulus
Membranous GN
A masson trichrome preparation shows complete replacement of virtually  all glomeruli by blue-staining collagen. Chronic  glomerulonephritis:
[object Object],[object Object],[object Object]
 
 
 
 
Section D about the subject of  Pathology, How to learn pathology?
Pathology ,[object Object]
Pathology   The Status of Pathology in Medicine a bridging discipline the clinical practice of medicine basic science
Learning Pathology: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Subdivisions of Pathology: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Past and Present….! ,[object Object],[object Object]

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Preface

Editor's Notes

  1. 1