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The
extracellular
matrix
ECM
The area
between
cells
The ECM of animal cells
• Animals cells lack
the structure and
support that a cell
wall provides
• Have an ECM
instead that
provides some of
the same support
Components of the ECM
• Cells secrete
glycoproteins
– This is the main
component of the
ECM
All 3 of these
are common
ECM
glycoproteins
• Collagen is the most common glycoprotein
in the ECM
• Proteoglycans (a
glycoprotein) form
a woven network
outside cells
• Collagen are like
strong fibers that
run throughout
this network
• Cells are attached to
the ECM by another
glycoprotein:
fibronectin
• On one side,
fibronectin is attached
to proteins in the
plasma membrane
• On the other side, the
fibronectin is attached
to the glycoproteins
of the ECM
Quick Think
Explain the role
of:
•Fibronectins
•Collagen fibers
•Proteoglycans
in the
extracellular
matrix
The ECM allows for cell to cell
communication
Intercellular junctions
• Cells in plants and animals are organized
into tissues, organs, and organ systems
• Cells in a tissue may adhere to each other
The Plasmodesmata of plants
• Cells walls of plants
are perforated with
small channels called
plasmodesmata
• Cytosol passes
through the channel,
thereby connecting
the two cells
• Water, solutes,
even proteins
and RNA can
move between
cells
• Allows plant
cells to function
as a unified
system, rather
than isolated
cells
Intercellular Junctions in Animal
Cells
• 3 main types of
junctions
between animal
cells
• These junctions
are most
common in
epithelial tissue
(skin, linings of
organs, etc)
Tight junctions in animal cells
• The plasma
membranes of
neighboring cells are
very tightly pressed
together and bound
by proteins
• Forms a seal or
barrier around a
group of cells
Desmosomes or anchoring
junctions in animal cells
• Like rivets that
fasten cells
together in strong
sheets
• Keratin filaments
anchor these
attachments in
the cytoplasm
Gap junctions (or communicating
junctions) in animal cells
• Similar to
plasmodesmata in plant
cells
• Provides a channel
between cells that
cytosol can travel
through
• Allows for cell to cell
communication
– Important in cardiac
tissue and embryonic
tissue
Quick Think:
Summarize the role and location of each of the 3
types of intercellular junctions

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AP Bio Ch. 7 part 2 The extracellular matrix

  • 2. The ECM of animal cells • Animals cells lack the structure and support that a cell wall provides • Have an ECM instead that provides some of the same support
  • 3. Components of the ECM • Cells secrete glycoproteins – This is the main component of the ECM All 3 of these are common ECM glycoproteins
  • 4. • Collagen is the most common glycoprotein in the ECM
  • 5. • Proteoglycans (a glycoprotein) form a woven network outside cells • Collagen are like strong fibers that run throughout this network
  • 6. • Cells are attached to the ECM by another glycoprotein: fibronectin • On one side, fibronectin is attached to proteins in the plasma membrane • On the other side, the fibronectin is attached to the glycoproteins of the ECM
  • 7. Quick Think Explain the role of: •Fibronectins •Collagen fibers •Proteoglycans in the extracellular matrix
  • 8. The ECM allows for cell to cell communication
  • 9. Intercellular junctions • Cells in plants and animals are organized into tissues, organs, and organ systems • Cells in a tissue may adhere to each other
  • 10. The Plasmodesmata of plants • Cells walls of plants are perforated with small channels called plasmodesmata • Cytosol passes through the channel, thereby connecting the two cells
  • 11. • Water, solutes, even proteins and RNA can move between cells • Allows plant cells to function as a unified system, rather than isolated cells
  • 12.
  • 13. Intercellular Junctions in Animal Cells • 3 main types of junctions between animal cells • These junctions are most common in epithelial tissue (skin, linings of organs, etc)
  • 14.
  • 15. Tight junctions in animal cells • The plasma membranes of neighboring cells are very tightly pressed together and bound by proteins • Forms a seal or barrier around a group of cells
  • 16. Desmosomes or anchoring junctions in animal cells • Like rivets that fasten cells together in strong sheets • Keratin filaments anchor these attachments in the cytoplasm
  • 17. Gap junctions (or communicating junctions) in animal cells • Similar to plasmodesmata in plant cells • Provides a channel between cells that cytosol can travel through • Allows for cell to cell communication – Important in cardiac tissue and embryonic tissue
  • 18. Quick Think: Summarize the role and location of each of the 3 types of intercellular junctions