Torque is a measure of the tendency to cause rotation and is determined by three factors: the magnitude of an applied force, the direction of the force, and the location where the force is applied. Torque is calculated as the product of the force and the perpendicular distance from the axis of rotation, known as the moment arm. Newton's second law of motion can be applied to rotational systems by considering torque as the rotational analogue of force and angular acceleration as the rotational analogue of linear acceleration. The rotational inertia, which depends on the mass and how it is distributed relative to the axis of rotation, determines how difficult it is to change an object's rotational motion and is analogous to linear mass.
This PPT covers relative motion between particles in a very systematic and lucid manner. I hope this PPT will be helpful for instructor's as well as students.
This PPT covers relative motion between particles in a very systematic and lucid manner. I hope this PPT will be helpful for instructor's as well as students.
this is about center of mass, center of mass for complicated shapes, center of mass of hemisphere, center of mass of many particles, center of mass of solids, center of mass of uniform cylinder, center of mass of uniform rod
Physical Quantities--Units and Measurement--Conversion of UnitsKhanSaif2
This presentation covers physical quantities and their types, units and their types, conversion of units and order of magnitude in a very interactive manner. I hope this presentation will be helpful for teachers as well as students.
this is about center of mass, center of mass for complicated shapes, center of mass of hemisphere, center of mass of many particles, center of mass of solids, center of mass of uniform cylinder, center of mass of uniform rod
Physical Quantities--Units and Measurement--Conversion of UnitsKhanSaif2
This presentation covers physical quantities and their types, units and their types, conversion of units and order of magnitude in a very interactive manner. I hope this presentation will be helpful for teachers as well as students.
VTU Notes for Testing and commissioning of Electrical Equipment Department of Electrical and Electronics Faculty Name: Mrs Veena Bhat Designation: Assistant Professor SDM Institute of Technology Subject: Testing and Commissioning of Electrical equipment Semester: VII
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
2. Torque is a twist
or turn that tends
to produce
rotation. * * *
Applications are
found in many
common tools
around the home
or industry where
it is necessary to
turn, tighten or
loosen devices.
4. Torque is Determined by Three Factors:
• The magnitude of the applied force.
• The direction of the applied force.
• The location of the applied force.
20 N
Magnitude of force
40 N
The 40-N force
produces twice the
torque as does the
20-N force.
Each of the 20-N
forces has a different
torque due to the
direction of force. 20 N
Direction of Force
20 N
q
q
20 N
20 N
Location of force
The forces nearer the
end of the wrench
have greater torques.
20 N
20 N
5. Units for Torque
Torque is proportional to the magnitude of
F and to the distance r from the axis. Thus,
a tentative formula might be:
t = Fr Sin θ Units: Nm
6 cm
40 N
t = (40 N)(0.60 m)
= 24.0 Nm, cw
t = 24.0 Nm, cw
6. Direction of Torque
Torque is a vector quantity that has
direction as well as magnitude.
Turning the handle of a
screwdriver clockwise and
then counterclockwise will
advance the screw first
inward and then outward.
7. Sign Convention for Torque
By convention, counterclockwise torques are
positive and clockwise torques are negative.
Positive torque:
Counter-clockwise,
out of page
cw
ccw
Negative torque:
clockwise, into page
8. Example 1: An 80-N force acts at the end of
a 12-cm wrench as shown. Find the torque.
• Extend line of action, draw, calculate r.
t = (80 N)(0.104 m)
= 8.31 N m
r = 12 cm sin 600
= 10.4 cm
9. Calculating Resultant Torque
• Read, draw, and label a rough figure.
• Draw free-body diagram showing all forces,
distances, and axis of rotation.
• Extend lines of action for each force.
• Calculate moment arms if necessary.
• Calculate torques due to EACH individual force
affixing proper sign. CCW (+) and CW (-).
• Resultant torque is sum of individual torques.
10. Example 2: Find resultant torque about
axis A for the arrangement shown below:
300
300
6 m 2 m
4 m
20 N
30 N
40 N
A
Find t due to
each force.
Consider 20-N
force first:
r = (4 m) sin 300
= 2.00 m
t = Fr = (20 N)(2 m)
= 40 N m, cw
The torque about A is
clockwise and negative.
t20 = -40 N m
r
negative
11. Example 2 (Cont.): Next we find torque
due to 30-N force about same axis A.
300
300
6 m 2 m
4 m
20 N
30 N
40 N
A
Find t due to
each force.
Consider 30-N
force next.
r = (8 m) sin 300
= 4.00 m
t = Fr = (30 N)(4 m)
= 120 N m, cw
The torque about A is
clockwise and negative.
t30 = -120 N m
r
negative
12. Example 2 (Cont.): Finally, we consider
the torque due to the 40-N force.
Find t due to
each force.
Consider 40-N
force next:
r = (2 m) sin 900
= 2.00 m
t = Fr = (40 N)(2 m)
= 80 N m, ccw
The torque about A is
CCW and positive.
t40 = +80 N m
300
300
6 m 2 m
4 m
20 N
30 N
40 N
A
r
positive
13. Example 2 (Conclusion): Find resultant
torque about axis A for the arrangement
shown below:
300
300
6 m 2 m
4 m
20 N
30 N
40 N
A
Resultant torque
is the sum of
individual torques.
tR = - 80 N m Clockwise
tR = t20 + t20 + t20 = -40 N m -120 N m + 80 N m
14. Summary: Resultant Torque
• Read, draw, and label a rough figure.
• Draw free-body diagram showing all forces,
distances, and axis of rotation.
• Extend lines of action for each force.
• Calculate moment arms if necessary.
• Calculate torques due to EACH individual force
affixing proper sign. CCW (+) and CW (-).
• Resultant torque is sum of individual torques.
15. Newtons 2nd law and rotation
• Define and calculate the moment of inertia for
simple systems.
• Define and apply the concepts of Newton’s
second law.
16. Inertia of Rotation
Consider Newton’s second law for the inertia of
rotation to be patterned after the law for translation.
F = 20 N
a = 4 m/s2
Linear Inertia, m
m = = 5 kg
20 N
4 m/s2
F = 20 N
R = 0.5 m
a = 2
rad/s2
Rotational Inertia, I
I = = = 2.5 kg m2
(20 N)(0.5 m)
4 m/s2
t
a
Force does for translation what torque does for rotation:
17. Rotational Inertia
m2
m3
m
4
m
m1
axis
w
v = wR
Object rotating at constant w.
Rotational Inertia is
how difficult it is to
spin an object. It
depends on the mass
of the object and how
far away the object if
from the axis of
rotation (pivot point). Rotational Inertia Defined:
I = SmR2
19. Example 1: A circular hoop and a disk
each have a mass of 3 kg and a radius
of 20 cm. Compare their rotational
inertias.
R
I = mR2
Hoop
R
I = ½mR2
Disk
2 2
(3 kg)(0.2 m)
I mR
2 2
1 1
2 2 (3 kg)(0.2 m)
I mR
I = 0.120 kg m2
I = 0.0600 kg m2
20. Newton 2nd Law
For many problems involving rotation, there is an
analogy to be drawn from linear motion.
x
f
R
4 kg
w
t
wo 50 rad/s
t = 40 N m
A resultant force F
produces negative
acceleration a for a
mass m.
F ma
I
m
A resultant torque t
produces angular
acceleration a of disk
with rotational inertia I.
I
t a
21. Newton’s 2nd Law for Rotation
R
4 kg
w
F wo 50 rad/s
R = 0.20 m
F = 40 N
t = Ia
How many revolutions
required to stop?
FR = (½mR2)a
2 2(40N)
(4 kg)(0.2 m)
F
mR
a
a = 100 rad/s2
2aq wf
2 - wo
2
0
2 2
0
2
(50 rad/s)
2 2(100 rad/s )
w
q
a
q = 12.5 rad = 1.99 rev
22. Summary – Rotational Analogies
Quantity Linear Rotational
Displacement Displacement x Radians q
Inertia Mass (kg) I (kgm2)
Force Newtons N Torque N·m
Velocity v “ m/s ” w Rad/s
Acceleration a “ m/s2 ” a Rad/s2