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THEILERIOSIS
By:
Dr. Yasmeen Ahmed
Dr. Ajay Srivastava
INDIAN VETERINARY RESEARCH
INSTITUTE
INTRODUCTION
ETIOLOGY
 CATTLE ,BUFFALO,WATER BUFFALO:
• THEILERIA ANNULATA
• THEILERIA PARVA
• THEILERIA MUTANS
• THEILERIA LAWRENCI
 SHEEP:
• THEILERIA HIRCI
• THEILERIA OVIS
 CAMEL:
• THEILERIA CAMELENSIS
 WHITE TAILED DEER:
• THEILERIA CERVI
• REINDEER:
• THEILERIA TARANDI
EPIDEMIOLOGY
LIFE CYCLE
PATHOGENESIS
SUPERFICIAL LYMPH NODES SWELLING AND EMACIATION
PATHOGENESIS
pathogenesis
NECROTIC AREAS IN BRAIN
MAJOR CLINICAL SIGNS
CLINICAL SIGNS
CLINICAL SIGNS
PUNCHED NECROTIC ULCER IN
ABOMASUM
DIAGNOSIS
DIAGNOSIS
PUNCHED NECROTIC ULCER IN
ABOMASUM
BLOOD SMEAR WTH
PIROPLASM
EMACIATION AND SWELLED
LYMPHNODE
KOCH BLUE BODIES PRESENCE OF IXODID
TICK
DIFFERENTIAL
DIAGNOSIS
DIFFERENTIAL
DIAGNOSIS
DIFFERENTIAL
DIAGNOSIS
DIFFERENTIAL DIAGNOSIS
DIFFERENTIAL DIAGNOSIS
TREATMENT
 Tetracyclines(@5-10mg/kgB.W.)- used earlier
 Broad spectrum antibiotics like
oxytetracycline(@10mg/kgB.W.),chlortetracycli
ne (only against schizontal stages)
 Buparvaquone(butalex,bupaven,zubion ,
50mg/ml)@2.5mg/kgB.W.,im,2times48hrs
apart(for both schizontal and piroplasmal stage)
 Halofuginone lactate @1.2mg/kg b.w.ORALLY.
 Symptomatic treatment includes
ANTIPYERETICS
-e.g.paracetamol@10mg/kgB.W. and
ANTIINFLAMMATORY DRUGS
-e.g.meloxicam@0.2-0.3mg/kgB.W,
ANTIDIARREOALS-e.g.neblon powder@30-
50g ,b.i.d.,centrogyLM@4-6boli/day
 Supportive therapy also provided
HEMATINICS -e.g.ferritas,bolus@2boli/day
&inj@1ml/50kg,
imferon@0.5-1g/week
 Liver protectants and restoratives may also
be given,e.g.liv-52vet@1-2bolus,bid
PREVENTION & CONTROL
Control of vector i.e.ticks mainly of Hyalomma
spp. By application of insecticides(like
deltamethrin(butox,12.5mg/ml)2-3ml/litre of
water,ivermectin(hitek,neomec,1%w/v)@0.2mg/
kg,s/c) and rotational grazing(breaks the
transmission cycle between cattle &tick).
Exotic & Crossbred cows should be kept in tick
free shed.
Recovered Cattle are immune to homologous
challenge
Avoid nutritional stress
Chemoprophylaxis-
• Chlortetracycline@16mg/kgB.W..orally for8 days,or
• Rolitetracycline@4mg/kgB.W.,im,for3days in calves
• Immunoprophylaxis-
• “Infection and treatment method”-injection of
cryopreserved susp. Of sporozoits from ground up
infected tick
• IVRI,bareilley,have evolved culture attenuated
schizontal vaccine
• Rakshavac-T,indian
immunologicals,@3ml,s/c,primary vaccination
at2months age & revacc. After 3yrs.
REFERENCES
• Helminths,Arthropods and Protozoa of
domesticated animals : E.J.L.Soulsby
• A textbook of veterinary parasitology :
B.B.Bhatia,K.M.L.Pathak,D.P.Banergee
• Veterinary medicine :
O.M.Radostits,D.C.Blood,C.C.Gay
THANK
YOU

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Theileriosis.