This document discusses canine demodicosis, a parasitic skin disease in dogs caused by an overpopulation of Demodex mites in the hair follicles. It covers the etiology (Demodex canis mites), pathogenesis (mites enter follicles and multiply), clinical signs (alopecia, scaling, crusting of the skin), diagnosis (identifying mites in skin scrapings under a microscope), prognosis (guarded for generalized cases), and treatment (miticidal dips and oral medications). The life cycle and types of Demodex mites are also described.
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
Babesiosis is the diseased state caused by the protozoal (single celled) parasites of the genus Babesia. Infection in a dog may occur by tick transmission, direct transmission via blood transfer from dog bites, blood transfusions, or transplacental transmission.
www.petsgroomingtips.com is one of the front-runners in providing complete digital information to the pet owners, which would guide theme through various process of grooming their beloved kids. A shabby puppy or kitten not only appears dirty but soon infested with disease if not treated properly. Our various tutorials and free PDF guides cover every aspect of the grooming process.
Calf scours causes more financial losses to cow-calf producers than any health problem in their herds. Calf scours is not a single infection; it is a clinical signallied with several diseases characterized by diarrhea. Regardless of the cause, diarrhea prevents the absorption of fluids from the intestines; also, body fluids pass from the scouring calfs body into the intestines. A calf is about 70 percent water at birth.
The scouring calf loses fluids and rapidly dehydrates. In addition, dehydration is associated with loss of essential body chemicals (electrolytes)-sodium and potassium-and the buildup of acid. The scouring calf typically becomes dehydrated and suffers from electrolyte loss and acidosis. Infectious agents cause the prime damage to the intestine, but death from scours usually results from dehydration, acidosis, and loss of electrolytes. The identification of infectious agents which cause scours, is quiet essential for implementing effective preventive measures (Wenzel et al., 2009).
The skin is not only the largest organ of the body, but it also forms a living biological barrier with several functions.
Pyodermas are any pyogenic skin disease (has pus). Skin infections can be caused by bacteria (often Staphylococcal or Streptococcal) either invading normal skin, or affecting a compromised skin barrier
Some bacterial skin infections resolve without serious morbidity. However, skin infections can be severe and result in sepsis or death, particularly in vulnerable patient groups.
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
Babesiosis is the diseased state caused by the protozoal (single celled) parasites of the genus Babesia. Infection in a dog may occur by tick transmission, direct transmission via blood transfer from dog bites, blood transfusions, or transplacental transmission.
www.petsgroomingtips.com is one of the front-runners in providing complete digital information to the pet owners, which would guide theme through various process of grooming their beloved kids. A shabby puppy or kitten not only appears dirty but soon infested with disease if not treated properly. Our various tutorials and free PDF guides cover every aspect of the grooming process.
Calf scours causes more financial losses to cow-calf producers than any health problem in their herds. Calf scours is not a single infection; it is a clinical signallied with several diseases characterized by diarrhea. Regardless of the cause, diarrhea prevents the absorption of fluids from the intestines; also, body fluids pass from the scouring calfs body into the intestines. A calf is about 70 percent water at birth.
The scouring calf loses fluids and rapidly dehydrates. In addition, dehydration is associated with loss of essential body chemicals (electrolytes)-sodium and potassium-and the buildup of acid. The scouring calf typically becomes dehydrated and suffers from electrolyte loss and acidosis. Infectious agents cause the prime damage to the intestine, but death from scours usually results from dehydration, acidosis, and loss of electrolytes. The identification of infectious agents which cause scours, is quiet essential for implementing effective preventive measures (Wenzel et al., 2009).
The skin is not only the largest organ of the body, but it also forms a living biological barrier with several functions.
Pyodermas are any pyogenic skin disease (has pus). Skin infections can be caused by bacteria (often Staphylococcal or Streptococcal) either invading normal skin, or affecting a compromised skin barrier
Some bacterial skin infections resolve without serious morbidity. However, skin infections can be severe and result in sepsis or death, particularly in vulnerable patient groups.
This presentation includes all all Data related to scabies and pediculosis and will helpful who want to study about scabies and pediculosis and their respective types. One thing was kept in mind while making this presentation that all area regarding topic should cover
Eczema is a group of skin condition that causes inflammation and irritation to the skin and is otherwise called as dermatitis,
Scabies is also a itchy skin condition caused by mite called Sarcoptes scabiei.
Ring worm in domestic animals. Clinical signs and treatment in different animals
Ringworm is a common infection of the skin caused by fungi. They affect human and animal superficial keratinized tissue (hair, nail, and skin) caused by dermatophytes' invasion of keratinized epithelial cells and hair fibres. It has a distinctive character that is alopecia with or without crust formation in circular scaly areas . This disease is a widespread disease that exists in all animals and humans as well.
Etiology : -
Two species Isolated [ Microsporum and Trichophyton ]
Cattel ➞ T. verrucosum
Horses ➞ T. equinum, M canis and T. mentagrophytes
Dogs And Cats ➞ M. canis,M. gypseum and the T. mentagrophytes
Camel ➞ T.mentagrophytes
Epidemiology :-
occurs in all animal species in all countries but more commonly where animals are accommodated in dense groups, especially indoors and in young age are more susceptible .
Transmitted by Direct Contact with infected animals is the common method of spread
And Indirect contact with inanimate objects, particularly bedding, harness, grooming kits and horse blankets .
Pathogenesis:-
➢ Ringworm fungi attack keratinized tissues, particularly the stratum corneum and hair fibers, resulting in autolysis ofthe fiber structure, breaking off the hair, and alopecia.
➢ Exudation from invaded epithelial layers, epithelial debris and fungal hyphae produce the dry crusts which are characteristic of the disease.
➢ The lesions progress if suitable environmental conditions for mycelial growth exist, including a warm humid atmosphere, and a slightly alkaline pH of the skin. Ringworm fungi are all strict aerobes and the fungi die out under the crust in the center of most lesions, leaving only the periphery active.
Clinical signs:-
A-Cattle & buffaloes:
➢ The typical lesion is a heavy, gray-white crust raised perceptibly above the skin.
➢ The lesions are roughly circular and about 3 cm in diameter.
➢ In the early stages the surface below the crust is moist, in older lesions the scab becomes detached and pityriasis and alopecia may be the only obvious abnormalities.
➢ Lesions are most commonly found on the neck, head and perineum but a general distribution over the entire body may occur, particularly in calves, and in severe cases the lesions may coalesce.
B-Sheep & goats:
➢ The lesions occur on the head, rarely in the fleeced areas and, although they usually disappear in 4-5 weeks, the disease may persist in the flock for some months.
➢ The lesions are discrete, round, almost bald patches covered with a grayish crust.
➢ Similar lesions occur in goats, but they are distributed generally over all parts of the body.
Horses : -
➢ typically dry forms of the disease. characterised by small tufts of spiky hair which soon fall out .
➢ alopecic areas covered by greyish scales with an underlying dry integument .
Camel : -
➢ The Classic Lesion of Camel Ringworm is non-pruritic And Alopecic with a gray – white , Thick crust That Cant be pulled
Glanders is an infectious disease that is caused by the bacterium Burkholderia mallei. While people can get the disease, glanders is primarily a disease affecting horses. It also affects donkeys and mules and can be naturally contracted by other mammals such as goats, dogs, and cats.
Important Zoonotic disease and its prevention and control By: Dr.Manoj karkimanojj123
Zoonosis are those disease and infection which are naturally transmitted between animals and human. (WHO & FAO, 1959).
Zoonosis word derived from Greek word “ZOO” means Animals and “NOSES” means Disease.
One Health is not a new concept, but it has become more important in recent years because many factors have changed the interaction among human, animals and the environment. These changes have caused the emergence and re-emergence of many disease.
Diagnosis of fungal disease by Dr. Manoj karkimanojj123
Early diagnosis of fungal infection is critical for effective treatment. History, clinical signs, gross pathology and in few cases intradermal skin test are all of the value in the diagnosis of clinical specimens.
Equine play an important role in rural communities providing power and transport at low cost. They can be used for various agricultural operations such as ploughing, planting and weeding. They also provide the much-needed transport in rural areas for activities such as carrying water, building materials, agricultural products and people.
Animal welfare refers to the relationship people have with animal and the duty they have to assure that the animal under their care are treated humanely and responsibly.
Rabies its transmission, clinical features and preventionmanojj123
Many people think that rabies is transmitted through only dog. But its not true, rabies is transmitted through not only dog, but also spread through bite or scratch from rabies infected animal like dog, bats, raccons, fox, monkeys etc.. Any open wound exposed saliva of infected animal can be potential source of infection.
Many European countries and North America have already eliminated rabies as a public health problem through mandatory vaccination of dog and good access to post exposure prophylaxis for human beings.
More than 95% of human death occurs in Asia/ Africa. And 99% of human rabies cases came from dogs. There is a small proportion of human rabies reported due to transmission via wild life (such as fox, wolves, jackels, raccoon, bats). Rabies kills more than 60,000 people each year (that is one death in every 9 minute) over 150 countries.
prevalence of fasciola hepatica in domesticated animal and its control and pr...manojj123
Fasciola hepatica also called (Liver fluke) is a parasitic disease caused by infection of trematode belongs to genus (F. hepatica, F. gigentica). Fasciola hepatica is distributed worldwide and cause great economic loss in livestock sector. Infected animal become anemic and loss of significant amount of weight.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
3. Introduction
• Canine demodicosis is a severe parasitic skin disease of a dog
caused by overpopulation of the follicular mite of various
demodex species.
• One of the most common cutaneous infection encountered in
canine practice is demodicosis.
• Demodex mites are normal flora localized in the skin of most
apparently healthy dog, when Secondary bacterial infection of
the hair follicle often occurs, and rupture of the hair follicle wall
may lead to presence of free mites in the dermis and a severe
pyogenic infection.
• .
4. • Although, demodex canis is acquired by puppies within the first few hours of
suckling it is a normal inhabitant of canine skin and demodicosis is not a
contagious disease
• Fig: 1. Life cycle of Demodex canis: (1) the life cycle of Demodex includes, apart from the adult mite,
egg, larva, and two nymphal stages; (2) the lifecycle happens in hair follicles. The puppy is infected by
the dam during the first days of its life. The infestation is preceded by the multiplication of the mites
on the dam’s skin (3). The mechanism, which accelerates the multiplication just before whelping, is not
known. Most dogs harbor single, latent Demodex mites in their hairfollicles, living in quiet seclusion.
In some individuals and in some circumstances the mites can start to multiply uncontrollably, leading
into the symptomatic demodicosis.
5. Etiology:
• Demodex canis is the main causative agent of canine
demodicosis.
• The mites residue in the hair follicle and sometimes the
sebaceous gland.
• Four stage are seen, the diamond shaped egg, the 6 legged
larvae and 8 legged nymph form which develops into adult.
• Generally three types of Demodex mites are found in dog.
Demodex canis (long bodied mites), Demodex injai (large
bodied mites) and Demodex cornei (short bodied mites)
6. Fig:2. Demodex canis and Demodex
cornei (blue box) at 10× magnification.
Fig:3. Demodex
injai (10×magnification)
7. Pathogenesis:
• The mites enter the hair follicle, reach the root and multiply.
• Due to inflammation the papilla is destroyed and the hair is lost.
•
• The parasite then enter the sebaceous gland where condition
appear to be very congenial for the growth of mites, since the
altered sebum is very favorable medium for them to grow.
• The sebaceous gland may be dilated and become cystic and
lined by squamous epithelium.
8. Conti…
• Thus the skin comes to be covered by scaly material which may
be desquamated.
• The sebaceous cyst may rupture, the spilled sebum causing
inflammation locally.
• The blood vessels are congested and dilated.
9. Clinical sign:
• The most common clinical sign are alopecia, scaly-crustly
thickened skin with hyperpigmentation, leechinification,
erythema, pruritus and seropurulent discharge seems mostly on
per ocular area, face, neck, shoulder and fore quarter region.
• Anemia may also occur in this condition due to loss of skin
proteins and leukocytosis.
• Most case of demodecosis are non-pruritus unless there is
secondary pyoderma.
10. Conti….
• Very rare ulceration may develop, especially on the face and
mucocutaneous area which may mimic autoimmune disease.
• Canine demodectic mange is classified as two forms.
• Localized and Generalized form
11. Localized form:
• The localized form typically starts as one or more focal alopecic
lesion, erythema and comedomes in dog less than 1.5 years old.
• Usually only the head (perioral, peri ocular) or the forelimb are
involved.
• There is no significant pruritus. This is commonly seen in pups
of 3 to 9 month old and spontaneous recovery without
treatment.
12. Generalized form:
• Generalize demodicosis is a severe disease requiring aggressive
therapy.
• This form involves the large part of the dogs skin and bears a
guarded prognosis.
• Generalized form is however, characterized by number of area
of localized disease or even infection in entire skin areas.
• Generalized demodicosis can be severe often complicated with
secondary bacterial infection and life threatening.
13. Conti….
• It should be remember that every case of generalized
demodicosis was localized form.
• Juvenile onset demodicosis (onset prior to puberty) and adult
onset demodicosis
• Juvenile onset is by far the most common and although a
serious disease, often a better prognosis than does adult onset.
• Adult onset is usually associated with severe internal disease
and Is often very difficult to control.
14. Clinical sign
Fig:4. Dog with lesions at face and neck
regions Fig: 5. Alopecia and scale/crusts formation throughout
the body due to infestion of demodectic mite
15. Diagnosis:
• Canine demodicosis is usually diagnosis by identifying mites in
skin scrapping and hair plugs.
• Performing of skin scrapping:
• Some 3-5 site are selected for skin scrapping
• The hair, if present, is clipped
• The skin is gently squeezed between thumb and forefinger to
force the mites more superficially in the hair follicle.
• The skin is moistened with liquid paraffin or mineral oil
• Some is also placed on the slide
16. Conti…
• The skin is then scraped using a blunted scalpel blade until
capillary bleeding is observed.
• The material is transferred to the slide
• The entire slide is scanned using 10X objective
• Focus on suspicious area using the 40Xobjective if necessary.
• The proportion of live and dead mites of adult and young forms
and of eggs should be recorded.
17. Or
• The scraping was placed in the test tube and 10% KOH solution
was added.
• Then, the solution was gently heated (near up to the boiling)
with frequent shaking for about 5-10 min until all the debris was
digested.
• Often the solution was allowed to cool for some time and was
allowed to centrifuge at 2000 rpm for 10min, supernatant were
discarded and remaining sediment were a coverslip.
• The sediment was observed for mites with the help of
compound (10x) microscope.
18. Prognosis:
• The prognosis for juvenile onset localized demodicosis is very
good.
• The prognosis for juvenile for onset generalized demodicosis is
always guarded.
• The demodicosis mange upto 1 year of age were more
susceptible to infection and the highest prevalence of the
disease was found in winter season rather than summer or rainy
season.
• Demodicosis is highly prevalent in dog whose immune system
is distributed or not well developed. So it is highly
recommended that dog should be given proper nourishment,
immunization, deworming and care to avoid skin disorder like
demodicosis.
19. Treatment and control:
• Treatment should be occur in localized and generalized
demodicosis
• In localized, this is usually a self-limiting disease that cures
spontaneously. Treatment with parasiticides is usually not
warranted.
• But 10 % of case of localized demodicosis go on to become
generalized. Therefore whether or not treatment is given a
careful follow up is necessary.
• In generalized demodicosis, it can be one of the most frustrating
skin disease, one will ever treat.
20. • Specific treatment of demodectic mange are:
• Amitraz: 0.025% whole body dip applied every 2 weeks interval 5-8
application or till skin scraping are negative. Not recommended for
cat and puppy
• Ivermectin: 0.3-0.6 mg/kg bwt PO single dose
• Moxidectin: 0.4mg/kg bw POsingle dose
• Before application of medicine crust, scale and debris should be
removed with soap and shampoo.
• A course of antibiotic should be given to inhibit bacterial infection.
• Antibiotic therapy should be continued until the mite population is
well controlled.
•
21. Reference:
• Ashfaq, K., et al. (2019). “Alternative therapeutic approach to treat
canine demodicosis”. EC veterinary science 4.4 :251-256
• Islam, M.M., et al. (2000). “Prevalence and pathology of demodectic
mange in stray dog in Bangladesh”. Journal of science and
technology. 11: 118-121
• Shrestha, D., et al. (2015). “Prevalence of demodectic mange in
canine of KTM valley having skin disorder and its associated risk
factor”. Int. Appl sci biotechnol, vol 3(3): 459-463
• Salem, N.Y., et al. (2020). “Canine demodicosis hematological and
biochemical alteration”. Veterinary world.org., vol(13):68-72
• Bhatia, B.B., et al.(2016). “ text book of veterinary parasitology”. 4th
edition.
• Picture are taken from google.