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TESTICULAR TUMOR-
SEMINOMA
DR YLS
TESTIS HISTOLOGY
TESTICULAR TUMORS CLASSIFICATION
GERM CELL TUMORS
ETIOLOGY
SIGNS AND SYMPTOMS
TESTIS SELF EXAMINATION
GROSS PATHOLOGY
 WELL
DEMARKATED,HOMOGENOUS,SOLID,.
GREY WHITE TUMORS.
 SURFACE NODULARITY AND
LOBULATIONS MAY BE SEEN
HISTOPATHOLOGY
 SHEETS AND LOBULES OF TUMOR CELLS
SEPERTED WITH FIBROVASCULAR SEPTAE
 CYTOPLASM IS TYPICALLY PALE
(GLYCOGEN),ROUND CENTRAL NUCLEUS
WITH PROMINENT NUCLEOLI
 LYMPHOCYTIC INFILTERATION SEEN
 RARELY GERMINAL
CENTRES,ODEMA,CYSTIC
SPACES,GRANULOMAS,SYNCITIOTROPHO
BLASTS,FIBROSIS CAN BSEEN
HISTOPATHOLOGY
CLASSICAL AD SPERMATOCYTIC
SEMINOMA
CYTOLOGY
 DISCOHESIVE PATTERN OF LARGE CELLS
WITH MODERATE CYTOPLASM WITH
ROUND NUCLEUS AND PROMINENT
NUCLEOLI
 BACKGROUS SHOWS LYMPHOCYTIC
INFILTERATION
 CHAARECTERSITIC IS PRESCENCE OF
TIGROID BACKGROUND.
 SPECIAL STAIN-PAS POSITIVE
IMMUNOHISTOCHEMISTRY-
OCT3/4,CD117,D2-40,PLAP,SALL4
IHC IN TESTICULAR TUMORS
DIFFERNTIAL DIAGNOSIS
 EMBRYONAL CARCINOMA
 SPERMTOCYTIC TUMOR
 SERATOLI CELL TUMOR
 LYMPHOMA
 GRANULOMATOUS ORCHITIS
STAGING
TREATMENT PROTOCOL
7/31/19

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