Nipple discharge is common and expected during pregnancy as the breasts prepare for lactation. Physiological discharge is called colostrum early in pregnancy and milk later. Non-pregnant women may also experience milk discharge due to high prolactin levels. In pregnancy, women may see blood-stained, yellow, black, or clear discharges from one or both nipples due to benign breast conditions, skin disorders, or malignancies like Paget's disease or ductal carcinoma. Persistent or unilateral bloody discharge raises the possibility of cancer and requires investigation.
Secondary amenorrhoea by dr alka mukherjee dr apurva mukherjeealka mukherjee
The first step in the evaluation of any patient with secondary amenorrhea is a urine pregnancy test. Every contraceptive method has a failure rate, and anyone who is menstruating is potentially fertile, regardless of age. [5][6]
If the pregnancy test is negative, consider the clinical picture: hirsutism, acne, and a long history of infrequent and irregular menses suggest polycystic ovarian syndrome. By the Rotterdam criteria, a patient may be diagnosed with PCOS if she has two of the following: clinical or chemical hyperandrogenism, oligo- or amenorrhea, or polycystic ovaries on ultrasound. So if a patient has evidence of hirsutism and oligo- or amenorrhea, she can be diagnosed with PCOS without further laboratory testing or imaging.
If history and physical exam are not consistent with PCOS, a TSH should be ordered. Both hyper- and hypothyroidism can lead to menstrual dysfunction.
If TSH is normal, check a serum prolactin. Elevated serum prolactin suggests prolactinoma.
Seminar presentation by student under supervision of endocrinology specialist from HRPZ. References as mentioned in the slides. Mostly from Malaysia CPG.
Secondary amenorrhoea by dr alka mukherjee dr apurva mukherjeealka mukherjee
The first step in the evaluation of any patient with secondary amenorrhea is a urine pregnancy test. Every contraceptive method has a failure rate, and anyone who is menstruating is potentially fertile, regardless of age. [5][6]
If the pregnancy test is negative, consider the clinical picture: hirsutism, acne, and a long history of infrequent and irregular menses suggest polycystic ovarian syndrome. By the Rotterdam criteria, a patient may be diagnosed with PCOS if she has two of the following: clinical or chemical hyperandrogenism, oligo- or amenorrhea, or polycystic ovaries on ultrasound. So if a patient has evidence of hirsutism and oligo- or amenorrhea, she can be diagnosed with PCOS without further laboratory testing or imaging.
If history and physical exam are not consistent with PCOS, a TSH should be ordered. Both hyper- and hypothyroidism can lead to menstrual dysfunction.
If TSH is normal, check a serum prolactin. Elevated serum prolactin suggests prolactinoma.
Seminar presentation by student under supervision of endocrinology specialist from HRPZ. References as mentioned in the slides. Mostly from Malaysia CPG.
Etiology of the most common breast masses, Triple assessment approach And management of the common causes of the breast masses. Brief intro on anatomy and physiology of the breast.
Brief overview of Breast anatomy and clinical assessment of benign as well as malignant breast disease. This information is perfect for the level of Final Year medical students.
Ovarian tumors are abnormal growths on the ovaries, the female reproductive organs that produce eggs. Ovarian tumors can be noncancerous (benign) or cancerous (malignant). Many things can make you more likely to develop an ovarian tumor.
1. Breast / Nipple Discharge In
Pregnancy
PROF. M.C. BANSAL
MBBS., MS., FICOG. MICOG.
EX PRINCIPAL & CONTROLLER ,.
JHALAWAR MEDICAL COLLEGE & HOSPITAL
JHALWAR.
MGMC & HOSPITAL , SITAPURA , JAIPUR.
2. Nipple discharge In Pregnancy
Function of breast is to produce milk and
preparation for lactation start in early weeks of
pregnancy. Hence discharge from breast is expected
called cholostrum.
Later it is called milk .
Non pregnant women suffering from hyper
prolactinaemia may have milk discharge in varying
amount.
In pregnancy some women may report blood stained
, yellow discharge like pus , black colored discharge
from one or both the nipples.
3. Causes of nipple discharge in Pregnancy
Intrinsic to pregnancy (physiological).
Skin disorder—eczema.
Benign breast problem
Duct Ectasia.
Intraductal papilloma
Malignancy
Pagets disease of the nipple ( carcinoma
presenting at nipple )
Ductal carcinoma in situ ( this may occur
concurrently with an invasive carcinoma of breast).
4. Blood discharge from nipple
A persistent discharge , unilaterally , raises the
possibility of ductal carcinoma in situ or actual
carcinoma of breast.
Discharge is usually bright red and persistent.
Some women develop cupious discharge of blood ,
bilaterally , towards the end of pregnancy and in
puerperium .investigations are require but often no
serious pathology is detected. There is also no
explanation is available .
Both intra ductal carcinoma and ductal carcinoma in
situ can present with persistent clear discharge also.
5. Breast nipple discharge establishing the
diagnosis
History
Clinical examination of both the breasts and
maxillae.
Cytology of discharge.
Ultra sound scan and / or mammogram after
shielding the fetus in uteri.
If there is a mass lesion :
FNAC.
core biopsy.
excision biopsy.
6. Ducal ecstasies
There is no special relation with pregnancy.
It is no more than a nuisance value.
Ecstasies means dilatation of a hollow organ.
Primary problem is a nonspecific inflammatory condition labeled as
periodical mastitis.
Secondary bacterial infection when super imposed ecstasies
increases .
7.
8. Ductal Ectasia
It is typically seen in smokers of 30 -4oyrs women.
Discharge may be from multiple duct of both the nipples .
It can be of various colors and some times tinged with
blood .
Some women may have nipple inversion and facing
difficulty in feeding
Some time a fistula may develop following drainage of an
abscess, between a duct and ducal opening in nipple .,
which is eccentric to the nipple.
9. Paget’ s disease
Carcinoma presenting at the nipple.
Usual presentation is unhealed ulcer, but in some cases
complaint may be of slight discharge , with or without
blood , not having noticed the erosive / ulcerative lesion .
clinical examination is to be followed by scan and
biopsy.
It is to be differentiated from eczema , the most common
benign problem is often bilateral and affects periareolar
area rather the nipple. It is associated with itching and
florid inflammation . serum leaking from eczema may
stain the bra.
The management of Paget’s disease is on the line of
treatment of carcinoma irrespective of pregnancy.