This document discusses red blood cell disorders and anemias. It begins by listing common clinical presentations of red blood cell disorders such as fatigue, pallor, and spoon-shaped nails. It then defines various abnormalities seen in red blood cells under the microscope, such as elliptocytes, schistocytes, and spherocytes. The document further discusses ways to classify anemias, including based on underlying mechanisms like blood loss, increased red blood cell destruction, and decreased red blood cell production. Causes of anemia are outlined in each category, such as iron deficiency anemia, sickle cell anemia, and aplastic anemia. Symptoms of anemia in general are also provided.
For More Medicine Free PPT - http://playnever.blogspot.com/
For Health benefits and medicine videos Subscribe youtube channel - https://www.youtube.com/playlist?list=PLKg-H-sMh9G01zEg4YpndngXODW2bq92w
This Presentation of Hemolytic Anemia try to cover important Hemato-pathological aspects of Red cell membrane disorders ( Hereditary Spherocytosis, others ) , Enzymopathies ( G6PD deficieny, others ) and Hemoglobinopathies ( Thallasemia, SCA) and their differentiation. References includes Robbins pathology, Wintrobes atlas and text, and others
Erythrocyte Sedimentation Rate (ESR), a lecture for medical lab technicians at Baquba Technical Institute, Middle Technical University. All theoretical and practical notes about the test.
For More Medicine Free PPT - http://playnever.blogspot.com/
For Health benefits and medicine videos Subscribe youtube channel - https://www.youtube.com/playlist?list=PLKg-H-sMh9G01zEg4YpndngXODW2bq92w
This Presentation of Hemolytic Anemia try to cover important Hemato-pathological aspects of Red cell membrane disorders ( Hereditary Spherocytosis, others ) , Enzymopathies ( G6PD deficieny, others ) and Hemoglobinopathies ( Thallasemia, SCA) and their differentiation. References includes Robbins pathology, Wintrobes atlas and text, and others
Erythrocyte Sedimentation Rate (ESR), a lecture for medical lab technicians at Baquba Technical Institute, Middle Technical University. All theoretical and practical notes about the test.
Anemia And Its Classification By Dr Bashir Ahmed Dar Chinkipora Sopore KashmirProf Dr Bashir Ahmed Dar
Anaemia due to iron deficiency is the characteristic finding with a cancer of the colon (large bowel), stomach or gullet. Often the anaemia is the only clue to the presence of a bleeding source somewhere. Any person who develops iron deficiency anaemia with no obvious cause should be investigated for the presence of a bleeding point within the digestive system. Fortunately not all bleeding sources turn out to be cancers
23. The nucleated RBC in the center contains basophilic stippling of the cytoplasm. This suggests a
toxic injury to the bone marrow. Such stippling may also appear with severe megaloblastic
anemia.
26. Here is data from a CBC in a person with iron deficiency anemia. Note the low
hemoglobin (HGB). Microcytosis is indicated by the low MCV (mean corpuscular
volume). Hypochromia correlates here with the low MCH (mean corpuscular
hemoglobin).
27. The CBC here shows a markedly increased MCV, typical for megaloblastic anemia. The
MCV can be mildly increased in persons recovering from blood loss or hemolytic
anemia, because the newly released RBC's, the reticulocytes, are increased in size over
normal RBC's, which decrease in size slightly with aging.
28. This CBC demonstrates findings suggestive of spherocytosis, a condition in which the
RBC's are small and round (rather than the normal biconcave appearance) with
increased hemoglobin content. This is indicated here by the increase MCHC (mean
corpuscular hemoglobin concentration). There is a rare condition known as hereditary
spherocytosis. Also, RBC's in the condition of autoimmune hemolytic anemia can also
appear similarly.
30. Symptoms of Anemia
• Fatigue
• Shortness of breath
• Dizziness
• Pale or yellowish skin
• Swollen tongue that may appear dark red
• Weight loss
• Diarrhea
• Numbness or tingling in your hands and feet
• Muscle weakness
• Irritability
• Unsteady movements
• Mental confusion or forgetfulness
31. Anemia
Definition:
Decrease in hemoglobin concentration
below the normal value for the age, sex
and for the given individual
32. Classification of anemias
There are many classifications of anemia
• Based on underlying mechanisms
• Morphologic characteristics
33. Anemias due to BLOOD LOSS
Mechanism Specific Examples
BLOOD LOSS
Acute blood loss Trauma
Chronic blood loss Gastrointestinal tract lesions,
gynecologic disturbances