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Leucocyte Disorders - Case studies
This document contains several quiz cases related to disorders of leucocytes. Some key details include: - Case 1 asks about differentiating a condition from leukemoid reaction, the chromosomal abnormality involved, and treatment drugs. - Case 3 describes a 60-year-old male with splenomegaly and anemia. - Case 10 lists abnormal differential count findings in a 25-year-old male with fever. - Case 11 describes test results for a 60-year-old female with bone pain and asks for the diagnosis. - The document provides clues to identify people, medical conditions, and drugs related to hematology. It aims to test knowledge of disorders of white blood cells
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Leucocyte Disorders - Case studies
- 1. Disorders ofDisorders of LeucocytesLeucocytes QuizCasesQuiz Cases Dr.CSBR.Prasad, M.D.,
- 2. Case-1 What isyour diagnosis? • insert
- 3. • How todifferentiate this from leukemoid reaction? • Name the chromosomal abnormality • Name the drug used in the treatment of this condition • Name the causes for massive splenomegaly • Name the causes for basophilia
- 4. Case-2 What isshown in the slide and what is your diagnosis?
- 5. Case-3 60yo malewith huge spleen and anemia
- 6. Case-4 • A 60yo male patient with pain in left hypochondrium of 6 months duration • o/e huge spleen - crossing the mid line • Peripheral blood smear: – Leucoerythroblastic blood picture – Tear drop cells – Abnormal platelets • The most likely diagnosis is…..?
- 7. Case-5 Hemogram forinterpretation.
- 8. Case-6 What doyou call these cells? Name the causative agent.
- 9. Case-7 Identify theabnormality in the smear.
- 10. Case- 8 25 yomale with fever of 1month duration.
- 11. Case-9 2 yofemalechild with petechiae, fever and lymphadenopathy of 1month duration. Peripheral blood smear is given below.
- 12. Case-10 How doyou interpret the following findings? • 25yo male with fever of 5days duration • Total leucocyte count 40,000 /cumm • Differential count: Neutrophils 70% Stab cells 20% Lymphocytes 5% Eosinophils 3% Monocytes 2% Basophils 0% • RBC parameters and Platelets are normal
- 13. Case-11 60 yofemale with bone pain. X-ray, Bone marrow and serum electrophoresis are given. What is your diagnosis?
- 14. Case-12 Where do you seethese abnormalities?
- 15. Q-1 Identify this person Usethe clues given
- 16. Q-2 Identify thepersonality (in 2009)
- 17. Identify the drugby using the clues
- 18.
- 19. Dr.CSBR.Prasad, M.D., Prof &HOD of Pathology, Sri Devaraj Urs Medical College, Kolar-563101, Karnataka. CSBRPRASAD@REDIFFMAIL.COM
Editor's Notes
- #10 Hypersegmented neutrophils, a feature of megaloblastic anemias, are not present in the nonmegaloblastic macrocytic anemias, except with myelodysplastic disorders.
- #15 1-Trisomy-8 karyotype 2-Trisomy 1 and monosomy 7 Both are seen in MDS.
- #17 Lisa Ray says she didn’t react after learning about her cancer: <TopNews.in> Submitted by Kiran Pahwa on Mon, 09/14/2009 - 16:18. Nevada (US), Sept 14 : Bollywood star Lisa Ray, who was recently diagnosed with incurable cancer, said that she didn’t react after learning that she had Multiple Myeloma. The Kasoor star revealed the shocking news on her blog last week, explaining she was battling Multiple Myeloma, a rare type of cancer of the bone marrow. The 37-year-old stunner told fans she learned of her disease in June (09) and started her first cycle of treatment weeks later. In her blog, she wrote that when she got the news, “I didn’t react and I didn’t cry”. “That’s how I felt after the diagnosis. Ok, I’ve got The Cancer. The tough part is over”, she adds. Acclaimed Indo-American statesman Rajan Zed has applauded Lisa’s fighting spirit and courage while triumphantly facing her toughest battle and staying optimistic and in great spirit. Lisa further writes in her blog: “Myeloma is incurable…I believe it can be cured…That’s the Dirty Realist in me…I’m aiming for Full Remission…I am humbled and inspired.” Although Lisa believes in alternative treatments/medication, but right now she has chosen not to mix therapies. She is going through chemotherapy which will finish in end of October and is aiming for a stem cell transplant and to be symptom free by December. Her treatments reportedly include heavy doses of dexamethasone and other steroids. (ANI) <http://www.topnews.in/lisa-ray-says-she-didn-t-react-after-learning-about-her-cancer-2213578> ========================================= Lisa Ray suffering from incurable Cancer: Lisa Ray Cancer Lisa Ray, who is Canadian born actress in toronto found with multiple myeloma on june 23, a rare cancer of the plasma cells. Which doctors are saying is “Incurable” and “Rare”… She has faith in herself that she will manage to get out of this disease… Lisa Ray’s Official blog : http://wwww.lisaraniray.com/home.html Lisa Ray wrote in her blog ‘The Yellow Diaries’ the tragic news yesterday i.e 8 september The 37-year-old actress was born to a Polish mother and Bengali father who belongs to India. The model-turned-actress decided to undergo medical examination a few months ago after she felt “exhausted, pale and drained” all the time. Lisa Ray started her career as model and then plunged into Bollywood movie through Kasoor in 2001 !
- #18 ATRA used in Acute promyelocytic leukemia t(15,17) causes “retinoid acid syndrome” which is characterized by weight gain, pleural and pericardial effusions, interstitial pulmonary infiltrates. In this case, retinoid acid should be stopped and treatment with cytostatic drugs must be started. Steroids may also be necessary.