This document summarizes several case studies involving lymphomas: Case 1 involves a 52-year-old female with enlarged lymph nodes and lung lesions. Biopsies of the lymph nodes and lung lesion were performed. Case 2 involves a 40-year-old female with gastric pain and abnormalities found during endoscopy. A gastric biopsy was performed. Case 3 involves a 5-year-old girl with a rapidly growing jaw swelling. Imaging and biopsies were performed to investigate. Case 4 involves a 70-year-old male being evaluated for weakness found to have lymphadenopathy. Testing of lymph nodes and bone marrow was done. The document discusses findings and next steps for each case

1. Case studies in Lymphomas
Dr.CSBR.Prasad, MD.,
March-2017-CSBRP

2. Case-1
• 52yo, F. complains of painless enlarging lumps in both axilla for the
past 3months
• She has weakness and dry cough since one month
• Chest radiograph reveled 1cm mass with irregular margins in the
right lower lung lobe
• CT failed to show any cavitation / calcification in the mass
• There is no hilar / mediastinal lymphadenopathy
• Local examination: Right axilla – matted lymphnodes meauring 5cm
in diameter. Left axilla – 4 discreet firm lymphnodes. There are two
discreet lymphnodes in the left upper cervical region
• There is no organomegaly
• CBC was normal
• ESR 80mm at the end of 1st hour
• FNAC of lung nodule was performed
March-2017-CSBRP

3. AP view
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4. Lateral view
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5. FNAC smear from lung lesion
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6. FNAC smear from right axillary lesion
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7. Excised axillary lymph node
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8. Excised axillary lymphnode
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9. Excised axillary lymphnode
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10. • What are your findings in the x-ray chest
• Describe the cytology smears
• Describe the gross appearance of lymphjnode
• What are the findings in histology of
lymphnode?
• What is your diagnosis?
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11. • What is the stage?
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12. Case-2
• 40yo, F. presented with h/o gastritis since
many years
• Recently she started to have persistent pain
abdomen
• Upper GI Endoscopy is given in the next image
• A gastric biopsy was done
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13. Endoscopic view of different regions of
stomach
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14. Low power
view of
gastric biopsy
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15. Closer view of gastric biopsy
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16. Case-2
• Describe the endoscopic findings ?
• What is shown in the gastric biopsy?
• What further test you want to do?
• If it is single lesion what is the usual mode of
treatment?
March-2017-CSBRP

17. Case-3
• 5yo, African girl
with rapidly
growing jaw
swelling of
2months duration
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18. Plain x-ray
MRI
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19. FNAC smear
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20. Biopsy from jaw lesion
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21. • Describe the clinical image
• What do your think of x-ray findings? Is it
malignant or benign?
• Describe the FNAC smear
• What are your findings in biopsy?
• What further test your do confirm your
diagnosis?
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22. Case-4
• 70yo, M. was evaluated for weakness
• o/e Patient had generalized non tender
lymphadenopathy
• CBC was done
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23. CBC report
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24. Peripheral Blood smear
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25. Lymphnode biopsy
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26. Bone marrow biopsy
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27. • What are abnormal findings in the CBC
report?
• Describe the peripheral blood smear?
• Describe the lymphnode biopsy. What those
arrows pointing to?
• What are your findings in BM biopsy?
• What is the nature of this lesion?
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28. Case-5 Can this be Hodgkin’s
Lymphoma?
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29. Case-6 Give your findings and DDs
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30. Case-7
Nuclear imaging
What is your most
probable diagnosis?
Based on what
findings?
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