Pulmonary tuberculosis is caused by the bacterium Mycobacterium tuberculosis. It is transmitted through airborne droplets when infected people cough, sneeze or talk. The bacteria are deposited in the lungs where they multiply and trigger an inflammatory response. Over time, granulomas form as the body tries to wall off the infection. Left untreated, the infection can spread throughout the lungs and to other parts of the body. Treatment involves a multi-drug regimen over several months to kill the bacteria and prevent drug resistance.
Emphysema is a type of COPD involving damage to the air sacs (alveoli) in the lungs. As a result, your body does not get the oxygen it needs. Emphysema makes it hard to catch your breath. You may also have a chronic cough and have trouble breathing during exercise. The most common cause is cigarette smoking
Rheumatic heart disease is a condition in which the heart valves have been permanently damaged by rheumatic fever. The heart valve damage may start shortly after untreated or under-treated streptococcal infection such as strep throat or scarlet fever.
Bronchitis is an inflammation of the bronchial tubes, the airways that carry air to your lungs. It causes a cough that often brings up mucus. It can also cause shortness of breath, wheezing, a low fever, and chest tightness. There are two main types of bronchitis: acute and chronic
Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose. Common symptoms are a stuffy nose, runny nose, sneezing, and post-nasal drip. The inflammation is caused by viruses, bacteria, irritants or allergens
Emphysema is a type of COPD involving damage to the air sacs (alveoli) in the lungs. As a result, your body does not get the oxygen it needs. Emphysema makes it hard to catch your breath. You may also have a chronic cough and have trouble breathing during exercise. The most common cause is cigarette smoking
Rheumatic heart disease is a condition in which the heart valves have been permanently damaged by rheumatic fever. The heart valve damage may start shortly after untreated or under-treated streptococcal infection such as strep throat or scarlet fever.
Bronchitis is an inflammation of the bronchial tubes, the airways that carry air to your lungs. It causes a cough that often brings up mucus. It can also cause shortness of breath, wheezing, a low fever, and chest tightness. There are two main types of bronchitis: acute and chronic
Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose. Common symptoms are a stuffy nose, runny nose, sneezing, and post-nasal drip. The inflammation is caused by viruses, bacteria, irritants or allergens
Bronchitis is an inflammation of the bronchial tubes, the airways that carry air to your lungs. It causes a cough that often brings up mucus. It can also cause shortness of breath, wheezing, a low fever, and chest tightness. There are two main types of bronchitis: acute and chronic.
Meningitis involves meninges
Viral meningitis
Bacterial meningitis
Fungal meningitis
Parasitic meningitis
Meningitis is an acute inflammation of the meningeal tissues surrounding the brain and the spinal cord (meninges).
Skipping vaccinations
Age-Viral meningitis occur in children younger than age 5. Bacterial meningitis is common in those under age 20.
Living in a community setting
Pregnancy.
Compromised immune system. AIDS, alcoholism, diabetes, use of immunosuppressant drugs etc.
Primary- Neisseria meningitidis
Secondary- E. coli
Haemophilus influenzae
Streptococcus pneumoniae
Meningitis involves meninges
Viral meningitis
Bacterial meningitis
Fungal meningitis
Parasitic meningitis
Meningitis is an acute inflammation of the meningeal tissues surrounding the brain and the spinal cord (meninges).
Skipping vaccinations
Age-Viral meningitis occur in children younger than age 5. Bacterial meningitis is common in those under age 20.
Living in a community setting
Pregnancy.
Compromised immune system. AIDS, alcoholism, diabetes, use of immunosuppressant drugs etc.
Primary- Neisseria meningitidis
Secondary- E. coli
Haemophilus influenzae
Streptococcus pneumoniae
More than 5.7 million new cases of TB (all forms, both pulmonary and extra-pulmonary) were reported to the World Health Organization (WHO) in 2013; 95% of cases were reported from developing countries
Latest figures from 20151 indicate an estimated 10.4 million people had TB, and 1.8 million people died (1.4 million HIV negative and 400 000 HIV positive).
Of further concern is that 480 000 cases of multidrug-resistant (MDR) TBa and a further 100 000 that were estimated to be rifampicin-resistant (RR) TB have occurred in the same period.
Bronchitis is an inflammation of the bronchial tubes, the airways that carry air to your lungs. It causes a cough that often brings up mucus. It can also cause shortness of breath, wheezing, a low fever, and chest tightness. There are two main types of bronchitis: acute and chronic.
Meningitis involves meninges
Viral meningitis
Bacterial meningitis
Fungal meningitis
Parasitic meningitis
Meningitis is an acute inflammation of the meningeal tissues surrounding the brain and the spinal cord (meninges).
Skipping vaccinations
Age-Viral meningitis occur in children younger than age 5. Bacterial meningitis is common in those under age 20.
Living in a community setting
Pregnancy.
Compromised immune system. AIDS, alcoholism, diabetes, use of immunosuppressant drugs etc.
Primary- Neisseria meningitidis
Secondary- E. coli
Haemophilus influenzae
Streptococcus pneumoniae
Meningitis involves meninges
Viral meningitis
Bacterial meningitis
Fungal meningitis
Parasitic meningitis
Meningitis is an acute inflammation of the meningeal tissues surrounding the brain and the spinal cord (meninges).
Skipping vaccinations
Age-Viral meningitis occur in children younger than age 5. Bacterial meningitis is common in those under age 20.
Living in a community setting
Pregnancy.
Compromised immune system. AIDS, alcoholism, diabetes, use of immunosuppressant drugs etc.
Primary- Neisseria meningitidis
Secondary- E. coli
Haemophilus influenzae
Streptococcus pneumoniae
More than 5.7 million new cases of TB (all forms, both pulmonary and extra-pulmonary) were reported to the World Health Organization (WHO) in 2013; 95% of cases were reported from developing countries
Latest figures from 20151 indicate an estimated 10.4 million people had TB, and 1.8 million people died (1.4 million HIV negative and 400 000 HIV positive).
Of further concern is that 480 000 cases of multidrug-resistant (MDR) TBa and a further 100 000 that were estimated to be rifampicin-resistant (RR) TB have occurred in the same period.
An inflammatory process in lung parenchyma usually associated with a marked increase in interstitial and alveolar fluid
the topic covers the
definition, etiology, Pathophysiology, Clinical manifestation, Diagnostic Evaluation, Medical Management, Nursing Management & nursing diagnosis.
tHESE SLIDES ARE PREPAREED TO UNDERSTAND about water born diseases IN EASY WAY Important links- NOTES- https://mynursingstudents.blogspot.com/ youtube channel https://www.youtube.com/c/MYSTUDENTSU... CHANEL PLAYLIST- ANATOMY AND PHYSIOLOGY-https://www.youtube.com/playlist?list=PL93S13oM2gAPM3VTGVUXIeswKJ3XGaD2p COMMUNITY HEALTH NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gAPyslPNdIJoVjiXEDTVEDzs CHILD HEALTH NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gANcslmv0DXg6BWmWN359Gvg FIRST AID- https://www.youtube.com/playlist?list=PL93S13oM2gAMvGqeqH2ZTklzFAZhOrvgP HCM- https://www.youtube.com/playlist?list=PL93S13oM2gAM7mZ1vZhQBHWbdLnLb-cH9 FUNDAMENTALS OF NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gAPFxu78NDLpGPaxEmK1fTao COMMUNICABLE DISEASES- https://www.youtube.com/playlist?list=PL93S13oM2gAOWo4IwNjLU_LCuhRN0ZLeb ENVIRONMENTAL HEALTH- https://www.youtube.com/playlist?list=PL93S13oM2gAPkI6LvfS8Zu1nm6mZi9FK6 MSN- https://www.youtube.com/playlist?list=PL93S13oM2gAOdyoHnDLAoR_o8M6ccqYBm HINDI ONLY- https://www.youtube.com/playlist?list=PL93S13oM2gAN4L-FJ3s_IEXgZCijGUA1A ENGLISH ONLY- https://www.youtube.com/playlist?list=PL93S13oM2gAMYv2a1hFcq4W1nBjTnRkHP facebook profile- https://www.facebook.com/suresh.kr.lrhs/ FACEBOOK PAGE- https://www.facebook.com/My-Student-S... facebook group NURSING NOTES- https://www.facebook.com/groups/24139... FOR MAKING EASY NOTES YOU CAN ALSO VISIT MY BLOG – BLOGGER- https://mynursingstudents.blogspot.com/ Instagram- https://www.instagram.com/mystudentsu... Twitter- https://twitter.com/student_system?s=08 #PEM, #water,#prification#largescale,#nurses,#ASSESSMENT, #APPEARENCE,#PULSE,#GRIMACE,#REFLEX,#RESPIRATION,#RESUSCITATION,#NEWBORN,#BABY,#VIRGINIA, #CHILD, #OXYGEN,#CYANOSIS,#OPTICNERVE, #SARACHNA,#MYSTUDENTSUPPORTSYSTEM, #rashes,#nursingclasses, #communityhealthnursing,#ANM, #GNM, #BSCNURING,#NURSINGSTUDENTS, #WHO,#NURSINGINSTITUTION,#COLLEGEOFNURSING,#nursingofficer,#COMMUNITYHEALTHOFFICE
Strategies in early HIV and role of a nurse. Nurses should know a strategies to identify diagnosis. based on this they can be able to provide effective nursing care strategies in alleviating the symptoms of HIV .Nurses are the front line care givers before somebody could provide care. Hence it is important for nurses to learn early strategies and nurses role in caring HIV patients.
Tuberculosis (TB) is caused by bacteria (Mycobacterium tuberculosis) that most often affect the lungs. Tuberculosis is curable and preventable.
TB is spread from person to person through the air. When people with lung TB cough, sneeze or spit, they propel the TB germs into the air. A person needs to inhale only a few of these germs to become infected.
The causative agent is Mycobacterium tuberculosis (also known as the tubercle bacillus).
Tuberculosis (TB) is an infectious disease that primarily affects the lung parenchyma. The primary infection usually involves the middle or lower lung area.
It is also may be transmitted to other parts of the body, including the Meninges, kidneys, bone, joints, pericardium, GI tract and lymph nodes And this condition known as Extra pulmonary TB.
The disease also can affects animals such as cattle, this is known as “bovine tuberculosis” which may sometimes be transmitted to man.The primary infectious agent, “ M.Tuberculosis”, is an acid – fast aerobic (AFB) rod that grows slowly and is sensitive to heat and ultraviolet light.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYNEHA GUPTA
The process of drug discovery and development is a complex and multi-step endeavor aimed at bringing new pharmaceutical drugs to market. It begins with identifying and validating a biological target, such as a protein, gene, or RNA, that is associated with a disease. This step involves understanding the target's role in the disease and confirming that modulating it can have therapeutic effects. The next stage, hit identification, employs high-throughput screening (HTS) and other methods to find compounds that interact with the target. Computational techniques may also be used to identify potential hits from large compound libraries.
Following hit identification, the hits are optimized to improve their efficacy, selectivity, and pharmacokinetic properties, resulting in lead compounds. These leads undergo further refinement to enhance their potency, reduce toxicity, and improve drug-like characteristics, creating drug candidates suitable for preclinical testing. In the preclinical development phase, drug candidates are tested in vitro (in cell cultures) and in vivo (in animal models) to evaluate their safety, efficacy, pharmacokinetics, and pharmacodynamics. Toxicology studies are conducted to assess potential risks.
Before clinical trials can begin, an Investigational New Drug (IND) application must be submitted to regulatory authorities. This application includes data from preclinical studies and plans for clinical trials. Clinical development involves human trials in three phases: Phase I tests the drug's safety and dosage in a small group of healthy volunteers, Phase II assesses the drug's efficacy and side effects in a larger group of patients with the target disease, and Phase III confirms the drug's efficacy and monitors adverse reactions in a large population, often compared to existing treatments.
After successful clinical trials, a New Drug Application (NDA) is submitted to regulatory authorities for approval, including all data from preclinical and clinical studies, as well as proposed labeling and manufacturing information. Regulatory authorities then review the NDA to ensure the drug is safe, effective, and of high quality, potentially requiring additional studies. Finally, after a drug is approved and marketed, it undergoes post-marketing surveillance, which includes continuous monitoring for long-term safety and effectiveness, pharmacovigilance, and reporting of any adverse effects.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
5. DEFINITION
ACCORDINGTO “ LEVIS COLLIER”
“tuberculosis is the bacterial
infectious disease transmitted by
mycobacterium tuberculosis”.
ACCORDINGTO “ LIPPINCOTT”
“ tuberculosis is a highly infectious
disease ,which is caused by mycobacterium
tuberculin and it is an acid fast aerobic rod that
grow slowly and it is sensitive to heat and
ultraviolet (uv) light ’’.
9. OTHER
Before pulmonary infection
Family history
Genetic factor
Smoking
Pollution
Secondary infection
Passive smoker
Person living in over crowed area
10. PATHOPHYSIOLOGY
Due to etiological factor
Microorganism enter the body by
airborne/droplet infection
Inflammation occur
The bacteria are transmitted through the airway
to the alveoli.
Where they are deposited and multiply.
The bacteria are also transmitted via the lymph
system and bloodstream to the other part of the
body
The body immune system respond by initiating an
inflammatory reaction.
11. Phagocytosis process occur ( neutrophils and
macrophages engoulph many of bacteria )
Specific lymphocytes lyses the bacilli and
normal tissue
This tissue reaction result in the accumulation
of exudates in the alveoli
New tissue masses called granulomas.
12. granulomas. new tissue masses of live and dead
bacilli are surrounding by microphages
granulomas. Are the transformed to a fibrous
mass
Tissue necrotic
The lead to excessive mucus production and
breathing difficulty
The lead to pulmonary tuberclosis
19. DIAGNOSTIC EVALUATION
DIAGNOSTIC FINDINGS:-
The diagnosis ofTB is made by a complete
history,physical examination,chest x-ray,acid fast
bacillus smer,sputum culture,and tuberculin skin
test.
the chest x-ray usauallay will reveal leision in the
upper lobes.
20. ,ACID FAST BACILLUS SMER,SPUTUM
CULTURE
An early morning sputum for an afb culture is
obtained.the afb smear indicate the
wheather mycobacterium is present
,indivating the diagnosis of tuberculosis
AFB smear—a microscopic examination of a
person's sputum or other specimen that is
stained to detect acid-fast bacteria. It is a
rapid test used to provide results within one
to two days. It is valuable in helping to make
decisions about treatment while waiting for
culture results
21. TUBERCULIN SKINTEST:-
the mantoux test is a skin test that is used to
determine if a person has been infected with theTB
bacilli.tubercle bacilli extract is injected into the
intradermal layer of the inner aspect of the
forearm,approximately 4 inches below the
elbow.intermediate strength of purified protein
derivative is used.using a ½ inches 26-27 needle is
inserted beneath the skin with the bavel of needle
up.then 0.1 ml ppd is injected ,created an elevation
in the skin ,the test is read 48-72 hrs after
injection.the tuberculin skin test is a delay localized
reaction which indicate the person is sensitive to
tuberculin.
22. MEDICAL MANAGEMENT
Pulmonary tuberculosos is treated ith chemotherapeutic agent
for a period of 6-12 month.five first line medication are used.
Resistance of m.tuberculosis to medication continues to be a
growing issue worldwide.the incidence of multidrug resistance
has created a new challange .several types of drug must be
considered when planning effective therapy.
Primary drug resistance is resistance to one of the first line
antituberculosis agent in a person who has not had previous
treatment.
Secondary drug resistance is resistance to one or more
antituberculosis agent in the patient under going therapy.
Multidrug resistance is resistance to a two agents,namely inh,rif.
23.
24.
25. compression of the heart by an accumulation
of fluid in the pericardial sac.
( compression of the heart by
an accumulation of fluid in the
pericardial sac cardiac
tamponade)
26.
27. NURSING PROCESS:-
ASSESSMENT
A complete history and physical examination are
performed ,clinical manifestation of fever
,anorexia,weight loss,night sweats,fatigue,cough
and sputum production prompt a more thorough
assessment of respiratory function.
28. NURSING DIAGNOSIS
Ineffective airway clearance releted copius
tracheobronchial secretion.
Activity intolerance releted to fatigue .
Self care deficit releted to chest pain
Anxity releted to blood in cough
29. GOAL
Maintenance of a patent airway .
Increased activity tolerance.
To improve the self care.
To increase the confidence level.
30. PLANNING
Maintenance of a patent airway.
To give the comfortable position .
Increasing fluid intake.
To give advice to wear humidity face mask or a humidifier.
Increased activity tolerance.
Working schedule is planned.
A nutrional plan that allows for small frequent meals may be required.
Liquid nutrional suppliments with high caloric requirement.
To improve the self care.
To increase the confedence level.
To give the proper nutrition.
To encourage the patient to do itself.
To increase the confidence level
To give the psychological support.
To encourage the patient to communicate to others.
To encourage the patient that he can do it.
31. OUTCOME
EXPECTED OUTCOMES
He will be free from difficulty in breathing.
IT will be a sense of well being.
He will be communicate to others.
He will be do it.
32. Health education
To advice the patient to give frequent diet.
To give the knowledge of common side effect.
Give the knowledge regarding disease and its
treatment.
Give health talk about diet and infection control.
Give health about the preventive measures.
To reassurance the patient.
To give all the knowledge regarding medication
and itd doses.
33. CONCLUSION
pulmonary tuberculosis is one of the too most
prominent microbacterium diseases known to human
kind the other is leprosy.it is the bacterial infection
disease transmitted by microbacterium tuberculie.it
usually involve the lungs ,but it also occur in the
kidney ,bones,lymph nodes and meninges and can be
disseminated through out the body.
The centre for disease control and prevention reports
an estimated 2 billion people or one third of the world
population are infected with the bacterium that cause
tuberculosis.the organism causingTB,is an extremely
opportunistic pathogens