Photoacoustic imaging
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Photoacoustic imaging uses the photoacoustic effect where pulsed or modulated light absorbed by a material sample causes a temperature increase and the expansion and contraction of the sample, generating ultrasonic pressure waves that are detected by transducers. Photoacoustic computed tomography reconstructs images from ultrasound wave data acquired by transducers as a laser illuminates a sample, while photoacoustic microscopy focuses a laser on and scans a sample in two dimensions. Applications include detecting brain lesions, monitoring hemodynamics, detecting prostate cancer, and endoscopy of the gastrointestinal tract.
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Project Kuwait
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Ftir
The document discusses Fourier transform infrared (FTIR) spectroscopy. It explains that FTIR spectroscopy uses a Michelson interferometer to obtain an infrared spectrum of a sample. The interferometer collects an interferogram that is then Fourier transformed to obtain the spectrum. FTIR spectroscopy provides advantages over dispersive infrared spectroscopy like speed, sensitivity, and mechanical simplicity. It finds applications in identifying organic and inorganic compounds, mixtures, and gases, liquids, and solids.
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Photoacoustic imaging
- 2. Photoacoustic effect Formation of acoustic waves due to absorption of light by the material sample Light intensity must vary with time - Periodic variation - Pulsed light
- 3. Photothermal Mechanism is most commonly used to explain photoacoustic effect The following steps are involved 1. Conversion of the absorbed pulsed or modulated radiation into heat energy. 2. Temporal changes of the temperatures at the region where radiation is absorbed 3. Expansion and contraction following these temperature changes, which get translated to pressure changes
- 5. Photoacoustic Computed Tomography(PAT) - Sample is illuminated by a laser beam - Variation in local absorption leads to generation of ultrasound waves which are recorded by ultrasonic transducer - Image is reconstructed from the data acquired by the transducers
- 6. The resolution is determined by the duration of the excitation laser pulse and the bandwidth of the transducers
- 7. Photoacoustic microscopy(PAM) - Laser beam is focussed on the sample - Sample is scanned in two dimensions
- 8. Uses - Brain Lesion detection - Hemodynamics monitoring - Prostate cancer detection - Gastrointestinal tract endoscopy
- 9. THANK YOU
Editor's Notes
- For this effect to be observed