The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
This lecture was prepared for second year MBBS students of Sir Salimullah Medical College, Dhaka. Here six cranial nerves are described in short and other six are described in detail. You are requested to see the youtube videos for understanding course of the cranial nerves. The lecture was delivered by Dr. Zobayer Mahmud Khan, lecturer, Departmenyt of Anatomy, SSMC.
Trigeminal nerve / orthodontic courses by Indian dental academyIndian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
This lecture was prepared for second year MBBS students of Sir Salimullah Medical College, Dhaka. Here six cranial nerves are described in short and other six are described in detail. You are requested to see the youtube videos for understanding course of the cranial nerves. The lecture was delivered by Dr. Zobayer Mahmud Khan, lecturer, Departmenyt of Anatomy, SSMC.
Trigeminal nerve / orthodontic courses by Indian dental academyIndian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
The anatomy of the nerve supply of the head and neck has many significant applications in maxillofacial surgery. Understanding these important anatomic relations- variations enables surgeons to perform the surgical procedures safely. Knowledge of these concepts helps us to recognize the problems and complications as and when they occur and manage them accordingly.
this presentation consist of introduction to types of nerves, structure of nerve and cranial nerves. there is a detail description about, origin , course of the trigeminal nerve and its branches and the structures supplying the nerve. it also contains applied anatomy of the nerve and its importance of the nerve in oral and maxillofacial surgeries. a detail description about the examination of the trigeminal nerve is also mentioned in the presentation. hoping that it would be useful to the students and people seeking for knowledge about the trigeminal nerve.
ORAL HABITS - DEFINITION, CLASSIFICATIONS, CLINICAL FEATURES AND MANAGEMENTKarishma Sirimulla
This seminar consists of description of various oral habit along with definitions, classifications, clinical features and management of oral habits like thumb sucking,tongue thrusting,mouth breathing and other secondary habits
This seminar consists of a brief description about various systemic diseases along with their oral manifestations and treatments along with the special considerations to be followed
This seminar consists of introduction, incidence, etiology, various classifications, history, clinical examination,sequelae of trauma of primary teeth followed by management
Pediatric Endodontics - Indirect and Direct pulp capping,Pulpotomy, Pulpecto...Karishma Sirimulla
this seminar consists of basis differences in root canal pattern between primary and permanet teeth followed by various definitions techniques and medicaments used in indirect pulp capping, direct pulp capping, pulpotomy, pulpectomy, apexogenesis and apexification
this seminar consists of pain,components of pain,pain pathways - ascending and analgesic followed by management of dental pain and local anesthesia,composition,various techniques used and pediatric implications for the administration of the locan anesthetics and the newer agents wich are available in topical,injectable and intra osseous techniques
This seminar contains a brief introduction followed by objectives of bahavior management,various definitions,classification,pedodontic triangle,parenting types,Non-pharmacological methods of behavior management in detail with modifications followed by conclusion.
This seminar consists of an introduction to child psychology followed by psychodynamic theories and its applicatioms followed by description and types of fear and anxietry followed by various behaviour rating scales and classification of behaviour
This seminar consisits of description of various bacterial diseases along with their oral manifestations,diagnosis and treatment.an addition of suitable case reports for better understanding and associated disorders
This seminar consists of various cysts seen in the oral cavity alonh with various classifications and added case repots for better understanding and the various treatment protocols followed for treating various cysts.
This seminar includes features of the normal periodontium seen in children along with various gingival and periodontal diseases seen in children with updated classifications along with clinical features and treatment modalities and a note on clinical assessment of oral cleanliness and periodontal diseases
Oral diseases: a global public health challenge and Ending the neglect of glo...Karishma Sirimulla
This presentation includes various lacunae faced by low and middle income contries due to the dental health policy and also highlights the areas where the reformation has to be made in order to utilize the dental services equally by all group of people
Diet and dental caries - Diet charts and Diet counsellingKarishma Sirimulla
This seminar includes a brief introduction to Diet and Dental caries along with Role of carbohydrates,Proteins and Fats with Dental caries along with diet charts, diet modifications, Diet counselling,Food log and sugar substitutes
Caries activity test - caries prediction,caries susceptibility and clinical i...Karishma Sirimulla
this seminar includes various caries activity tests and key caries risk factors caries susceptibility,cariogram and caries prediction along with its applications
This seminar includes classifcation,etiopathogenesis,Various theories of dental caries,caries patterns in primary and permanent teeth,Caries pattern in adolescets followed by caries risk assessment,CAMBRA,Differences between nursing bottle and rampant cariess,diagnosis which included the advanced digital diagnostic methods like diagnodent,QLF,etc and management with age specific management and flouride therapy age wise .
This seminar includes various cephelograms and various hard tissue analyses by diffreent authors followed by differences in various ethnicities and pediatric implications
This seminar includes various isolation methods which are direct and indirect with eloboration about rubber dam usage and application along with the advantages along with soft tissue isolation methods
This seminar includes hemostasis,mechanism of blood clotting and associated blood dyscrasias commonly seen in children and their treatments with a note on antifibrinolytics
Differences between primary and permanent teeth and importanceKarishma Sirimulla
This is a small brief presentation and contains basic differences between primary and permanent dentition an also an added note on importance of young permanent molar and its management clinically
THIS SEMINAR INCLUDES DEFINATION,TYPES OF INFLAMMATIONS AND MEDIATORS OF INFLAMMATION FOLLOWED BY REGENERATION,REPAIR AND WOUND HEALING BY PRIMARY AND SECONDARY INTENTIONS OF SOFT AND HARD TISSUES.HEALING OF EXTRACTION SOCKETS AND WEEKLY CHANGES IN HEALING OF EXTRACTION SOCKET.LOCAL AND SYSTEMIC FACTORS OF INFLAMMATION ABD COMPLICATIONS OF WOUND HEALING
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Neuroanatomy seminar with special reference to trigeminal,facial and glossopharyngeal nerve
1. z
NEUROANATOMY OF CRANIOFACIAL
STRUCTURES WITH SPECIAL
REFERENCE TO
TRIGEMINAL NERVE ,
FACIAL NERVE ,
GLOSSOPHARYNGEAL NERVE
AND CERVICAL PLEXUS
KARISHMA.S
I MDS
Pedodontics
R.V Dental college
2. CONTENTS
Terminologies
Functional components
Parts of nervous system
Cranial nerves
Trigeminal nerve
-course and branches
Facial nerve
- course and branches
Glossopharyngeal nerve
- course and branches
Cervical plexus
Conclusion
References
3. TERMINOLOGIES
NEURON : Structural & Functional unit of Nervous
System.
NUCLEUS: Applies to an aggregate of nerve cell bodies
located within the CNS.
GANGLION: is a collection of nerve cell bodies outside the
brain and spinal cord(CNS)
e.g: a) sensory ganglia of cranial nerves
semilunar , geniculate
b) parasympathetic ganglia
ciliary, submandibular
4. TRACT: defined as a group of nerve cell processes within
the CNS.
NERVE: is a bundle of neuronal processes outside the
CNS.
Sensory,
Motor,
Mixed.
PLEXUS: site regrouping of peripheral nerve fibers
deriving from diverse origins.
5. FUNCTIONAL COMPONENTS:
A cranial nerve consists of motor fibers or
sensory fibers or both motor and sensory fibers
TYPES:
MOTOR:
1. GSE: They supply the striated muscles which develop
from somites.These fibers convey motor
impulses to skeletal muscles.
2. GVE: They supply the glands,smooth muscles of
viscera and vessels.They are preganglionic
parasympathetic fibers.
3. SVE: They supply the muscles which develop from
mesoderm (special) of pharyngeal arches.
6. SENSORY:
1.GSA: They carry general sensations of pain, touch and
temperature from skin and proprioceptive sensation
of vibration and muscle and joint sense.
2.GVA: They carry general sensation of distention and
ischemic pain from viscera.
3.SVA: They carry special sensation of taste from tongue.
(special)
4.SSA: They carry special sensation of smell,hearing and
(special somatic) balance.
8. CENTRAL NERVOUS SYSTEM
Brain- control center of nervous system
receives sensory input from spinal cord as
well its own nerves.
Ex: olfactory, optic
It consists of six major parts
Cerebrum
Diencephalon
Midbrain
Pons
Medulla oblongata
Cerebrllum
Spinal cord- Conducts sensory information
from PNS to brain.Conducts motor
information from brain to
various effectors.
9. PERIPHERAL NERVOUS SYSTEM
It consists of
12 pairs of cranial nerves
31 pairs of spinal nerves
SPINAL NERVES :
8 pairs of cervical nerves (C1 – C8)
12 pairs of thorasic nerves (T1-T12)
5 pairs of lumbar nerves (L1-L5)
5 pairs of sacral nerves (S1-S5)
And one coccygeal pair of nerves
11. The peripheral nervous system is further divided into
a) Somatic b) Visceral
The somatic part innervates structures derived from somites in
the embryo,and is mainly involved in receiving and responding
to information from external environment.
The visceral part innervates organs and other visceral elements
such as smooth muscles and glands, in peripheral regions of
the body.It is concerned with detecting and responding to
information from the internal environment.
The visceral motor component is commonly referred as the
autonomic division of peripheral nervous system.
The visceral component is further divide into
a)sympathetic b)Parasympathetic
12. DIVISIONS OF ANS
SYMPATHETIC NERVOUS
SYSTEM:
contains chiefly adrenergic
fibers and tends to depress
secretions, decrease the tone and
contractility, and increase heart
rate. E.g : increase in heart rate,
slowing the movement of intestines.
PARA SYMPATHETIC NERVOUS
SYSTEM:
the part that contains chiefly
cholinergic fibers, that tends to
induce secretion, to increase the
tone and contractility , and to slow
heart rate E.g. : slowing heart rate,
speeding up movement of intestines
13. The cranial nerves carry efferent fibres that innervate the
musculature derived from the pharyngeal arches
First arch – Trigeminal nerve
Second arch – Facial nerve
Third arch – Glossopharyngeal
Fourth arch – Superior laryngeal branch of vagus nerve
Sixth arch – Reccurent laryngeal branch of vagus nerve
15. Largest cranial nerve
Nerve of 1st brachial arch
It carries general somatic afferent(GSA) and
brachial efferent fibres(BE)
The trigeminal ganglion has a small motor and
larger sensory root.
The trigeminal ganglion resides in the middle cranial fossa. It is
situated in a fold of dura mater that forms an invagination around
the posterior two-thirds of the ganglion. This region is referred to
as Meckel's cavity.
The motor root of trigeminal is connected with the
motor nucleus in the pons.
16. The sensory root is connected with the three
nuclei
Mesenchephalic – proprioception from muscles of
mastication from mandibular
nerve
Central pontine – fine touch fibers from face,and
mucosal areas from nose and
palate
Spinal nucleus – pain and temperature fibres.
The ganglion divides to form 3 divisions:
OPTHALMIC – V1
MAXILLARY – V2
MANDIBULAR – V3
17. OPHTHALMIC DIVISION [V1]
Exclusively Sensory & Smallest (trunk 2.5cm).
Enters Cavernous Sinus and comes out through
Superior Orbital Fissure.
3 main branches before leaving cavernous sinus:
i. Lacrimal (lateral most)
ii. Frontal
iii. Nasociliary (medially)
Lacrimal & Frontal enter outside the Common Tendinous Ring,
where as the nasocilliary branch enters inside the common
tendinous ring between the superios and inferior branches of
oculomotor nerve
18. The Lacrimal Nerve
• Smallest Branch of the 3 branches
• In orbit it passes along the upper border of the lateral rectus
• Receives branch from zygomatico temporal nerve(inf.orbital fissure),
which carries Parasympathetic and sympathetic post ganglionic fibers
to lacrimal gland.
• Supplies the lacrimal gland, conjunctiva & lateral Part of the upper
eyelid.
19. The Frontal Nerve
• Largest branch of the 3 branches
• Receives sensory input from areas outside the orbit
• From superior orbital fissure it passes forward between levator
palpebrae superioris and roof of orbit
About midway it divides into
a) supra trochlear
b) supra orbital
20. • Supra trochlear exits medial to supra orbital foramen and
supplies Conjuctiva, skin of upper eyelid and skin on lower
medial part of forehead.
• Supra orbital exits through supra orbital notch and ascends
across the forehead, scalp, eyelids,conjunctiva,as posteriorly as
middle of scalp
21. The NasoCiliary Nerve
• First branch of opthalmic division.
• Placed between superior and inferior branch of oculomotor nerve
• In the orbit it first branches with the ciliary ganglion and then
Continues forward to give:
22. Long Ciliary Nerve : sensory to eyeball which are 2 or 3 in number
supply the Iris & Cornea(pupillary dilation)
Post. Ethmoidal : supplies Ethmoidal & Sphenoidal sinuses.
Infra Trochlear : supplies medial part of upper and lower eyelid,
Lacrimal Sac & skin of upper half of nose.
Ant. Ethmoidal : supplies anterior cranial fossa,nasal cavity,skin of
lower half of nose.
23. Ciliary ganglion :
Located about 1cm anterior to the medial end of superior
orbital fissure.it is lateral to optic nerve and medial to
lateral rectus.
Functionally related to oculomotor nerve and anatomically
to nasociliary nerve.
Only parasympathetic branch rely in the ganglion where
as sensory and sympathetic only pass through the
ganglion
Sympathetic root is dervied from
internal carotid artery which
contains postganglionic fibers of
superior cervical ganglion.
24. Only parasympathetic rely in the ganglion where as sensory and
sympathetic only pass through the ganglion.
The parasympathetic fibers supply the ciliaris muscle of eye ball
and constrictor pupili.
Sensory nerves to the ciliary ganglion are through the maxillary
nerve which continues as nasociliary nerve.
Long ciliary nerve carries the general
somatic sensations from cornea iris and
ciliary body
Some general somatic fibers can also
enters the short ciliary nerve
25. Maxillary division [V2]
Purely sensory
Origin: middle of trigeminal ganglion
Exit from skull: through lateral wall of cavernous sinus exits
through foramen rotundum (located in sphenoid) supplying skin
of face, lower eyelid, nose & upper lip.
Leaves middle cranial fossa through rotundum into
Pterygopalatine Fossa and enters orbit through Inf. Orbital fissure
& becomes Infraorbital nerve
Branches in 4 regions:
- within the cranium
- in the pterygopalatine fossa
- in the infraorbital canal
- on the face.
26. Within the cranium
Small branch of the middle meningeal
nerve , which travels with middle
meningeal artery to provide sensory
innervations to duramater.
In the Pterygopalatine fossa
Branches given off are :
A) Zygomatic Nerve
(Z.facial,Z.temporal,communicating)
B) Pterygopalatine Nerves
C) Post. Superior Alveolar Nerve
27. In InfraOrbital Canal
Within this , it gives off 2 branches :
A) Middle Superior Alveolar nerve (infra orbital fissure)
B) Anterior Superior Alveolar nerve (infra orbital canal)
The superior dental plexus is formed by posterior, middle and
anterior alveolar nerves (PSA+MSA+ASA)
28. On Face
It emerges through the infraorbital foramen into it’s terminal
branches :
1. Inferior Palpebral-lower eyelid,conjuctiva
2. External Nasal-lateral part of nose
3. Superior Labial-upper lip
29. Pterygopalatine ganglion or sphenopalatine ganglion
Largest parasympathetic ganglion.it is a rely station of secretomotor fibers for
lacrimal glands,mucosal glands of nose,paranasal sinuses,palate and pharynx.
Anatomically related to maxillary nerve but functionally related to
• Internal carotid-through deep petrosal
• Facial nerve- through greater petrosal
Lies in pterygopalatine fossa in front of pterygopalatine canal.
Sensory root – from maxillary nerve
Sympathetic root – internal carotid
plexus(vasomotor supply)
Parasympathetic root – superior
salivatory nucleus(supplies secretomotor
nerves)
30. Post ganglionic fibers(secretomotor)
from the pterygopalatine ganglion
exit through the
1. inferior orbital canal to reach the
orbit to supply orbital mucosa.
2. Sphenopalatine foramen to give
medial and lateral branches.
nasopalatine branch i.e one of the
medial nerve continues downward
to exit through the incisive canal.
3. Greater palatine canal and gives
greater palatine and lesser
palatine nerves
4. Pharyngeal branch passes
through the palatinovaginal canal
to supply part of nasopharynx
31. Mandibular division [V3]
Unlike Ophthalmic[V1] and Maxillary[V2] which are purely
sensory,the mandibular nerve is both motor and sensory.
All braches of the mandibular nerve orginate in the infra
temporal fossa
SENSORY – Drops vertically through foramen ovale and enters
infra temporal fossa between tensor veli palatine and
lateral pterygoid.
MOTOR – Passes medial to the trigeminal ganglion in cranial
cavity and passes through foramen ovale and joins the
sensory nerve.
32. Branches of mandibular division
Branches from
undivided nerve:
- Nerve to median
pterygoid muscle
- Also sends motor
branches to
tensor veli palatini
tensor tympani
Branches from
divided nerve:
Anterior division
- Nerve to lateral
pterygoid
- To masseter muscle
- To temporal muscles
- Long buccal nerve*
- Meningeal
Posterior division:
-Auriculotemporal
-Lingual
-Inferior alveolar
-Nerve to mylohyoid*
33. BRANCHES INNERVATIONS
MENINGEAL Sensory for duramater,middle cranial
fossa,middle ear
LATERAL PTERYGOID Branch of anterior trunk of V3 ,passes directly
into deep lateralpterygoid
TO MASSETER MUSCLE passes over lateral pterygoid to supply
masseter muscle
DEEP TEMPORAL MUSCLE two in number, supplies temporalis muscles
from inside
LONG BUCCAL sensory nerves to skin,oral mucosa ,buccal
gingivae of lower molars
AURICULO-TEMPORAL Sensory innervations to external ear and
auditory meatus,tympanic membrane and TMJ
LINGUAL Gen sensation frm ant. 2/3rd,oral mucosa
and lingual gingivae of lower teeth
INFERIOR ALVEOLAR Supplies to the mandibular molars and
second premolar,then divides to supply
anteriors
MYLOHYOID Motor supply to mylohyoid muscle and
anterior belly of digastric
POSTERIOR
ANTERIOR
34. Branches from the Anterior Division
Significantly smaller than posterior division.
Provides motor innervation to the muscles of
mastication & sensory innervation to mucous
membrane of cheek & mandibular molars.
Runs forward between the upper border of Lateral
Pterygoid & gives off Buccal Nerve.
Gives off several branches :
1. Deep Temporal Nerve to Temporal Muscle
2. Massetric Nerve to Masseter.
3. Nerve to Lateral Pterygoid.
Sensory fibers are distributed over the skin of
cheek & other fibres run into the retromolar
triangle.
35. Branches from the Posterior Division
Primarily sensory with a small motor
component
Descends downward & medially to lateral
pterygoid at which it branches :
1. Auriculotemporal Nerve : traverses upper
part of the parotid & gives off sensory ,
secretomotor & vasomotor fibres to parotid.
2. Lingual nerve : passes downward parallel
to Inf. Alveolar nerve passes along the
hyoglossus and genioglossus to reach the
tongue
It is sensory to the anterior 2/3rd of tongue &
gives sensory innervation to the floor of the
mouth and to gingiva.
36. 3.Inferior alveolar and Nerve to mylohyoid:
It originates deep to the lateral
pterygoid muscle from posterior trunk of mandibular nerve in
association with lingual nerve.
• It descends between sphenomandibular ligament and ramus of
mandible and enters the mandibular canal through mandibular
foramen.
• Just before entering it gives origin to nerve of the mylohyoid
which lies in mylohyoid groove to innervate mylohyoid muscle
and anterior belly of digastric muscle.
• It supplies to the three molars and second premolar and then
divides into
• Incisive nerves
• Mental nerves
37. Applied anatomy/ 5th nerve
TRIGEMINAL NEURALGIA : or tic douloureux
It is a complex sensory disorder of sensory root of trigeminal
nerve, characterized by extremely severe shock like or lancinating
pain limited to one or more branches of trigeminal nerve.
Etiology:
damage to myelin sheath,blood vessel compression,injury
during surgery or trauma
C/F: persons > 50 yrs
women > men
right side > left
Pain searing, stabbing or lancinating
Initiated by touching trigger zone
Spasmodic contractions of facial muscles
Types:
1.typical/classic
2.atypical
38. 1st line of treatment is medication like
Carbamezapine , Gaba pentin ,
Phenytoin.
Tricyclic antidepressants like
amitriptyline,nortriptyline.
Later other procedures can be
considered like
Rhizotomy/Rhizolysis(nerve fibers are
damaged to block the pain)
1. Ballon compression
2. Glycerol injection
3. Stereotactic radiosurgery
4. Microvascular decompression
5. Neurectomy
6. Compensatary approaches(botulin
toxin injection)
39. FREY’S SYNDROME
It is the damage to auriculotemporal nerve
& subsequent reinnervation of sweat glands.
Etiology: caused due to either sequelae of
parotidectomy or any other surgical
or traumatic injuries
C/F: Flushing & sweating on ipsilateral facial
skin during mastication
Treatment:
- By topical anticonvulsant medications
- Glycopyrolate roll-on lotion
- Intra cutaneous injection of botulinum
toxin
40. Refactory Trigeminal Neuralgia successfully treated by combination therapy
(Pregabalin plus Lamotrigine).Unit of Rehabilitation and Functional Recovery, IRCCS Istituti Clinici Scientifici Maugeri, Lissone
(MB), Italy. Electronic address: giorgio.ferriero@icsmaugeri.it.
Trigeminal Neuralgia (TN) that is probably the most widely recognized neurophatic pain syndrome with
a prevalence range from 1.9% to 6.3%.TN treatment primarily consists of antiepileptic medications
acting on voltage-dependent sodium channels, such as Carbamazepine (CBZ) and Lamotrigine (LTG).
CBZ is reported to be not well tolerated by Multiple sclerosis patients for its side effects that mimic an
Multiple sclerosis exacerbation. In order to reduce side effects occurrence both CBZ and LTG were
successfully used in association with Gabapentin suggesting combination therapy as a useful
therapeutic strategy.
Pregabalin (PGB) is an antiepileptic drug (AED), selective ligand for α2δ subunit dependent on voltage
calcium channels. Potential binding at this site reduces calcium influx at hyper-excited nerve terminals
and the release of several neurotransmitters, including glutamate, noradrenaline and substance.PGB
was successfully used in treating paroxysmal symptoms in Multiple sclerosis patients.
42. -Nerve of 2nd Brachial Arch.
-Motor nerve to the muscles of Facial Expression
-Has both Sensory & Motor Functions
Functional components
SVE – muscles of facial expressions
GVE – secretomotor to submandibular,lingual and
lacrimal glands,glands of nose,palate and pharynx
SVA – carry taste sensation from anterior 2/3rd of
tongue.
GSA – these fibers innervate the ear
Exit from skull: in a bony canal at stylomastoid
foramen
FACIAL NERVE
43. Facial nerve Nuclei
Arise from 4 nuclei situated in lower pons:
i. Motor nucleus : Branchiomotor nucleus
ii. ParaSympathetic: Superior salivatory
and lacrimatory
iii. Nucleus of tractus solitarius : is
Gustatory
Ganglia associated :
i. Geniculate ganglia
ii. Submandibular ganglia &
iii. Pterygopalatine ganglia.
44. Intracranial Course of Facial Nerve
Attached to the brainstem by 1 sensory & 1
motor root.
The 2 roots run laterally with the 8th nerve to
reach Int. Auditory Meatus, & at the bottom
fuse to form a single trunk.
Within the canal , the course can be divided
into 3 parts by 2 bends :
1. 1st part directed laterally over vestibule.
2. 2nd part runs backward above
Promontory.
3. 3rd part directed vertically downward
behind Promontory.
The 1st bend is sharp & is known as GENU as
Geniculate Ganglion is present.
1
2
3
45. Branches of distribution of Facial nerve
I. Within the
facial canal :
a) Greater Petrosal
Nerve
b) Nerve to Stapedius
c) The Chorda
Tympani
II. At its exit from
stylomastoid foramen
:
- Nerve to Stylohyoid
- Nerve to Digastric
- Posterior Auricular
Nerve
Terminal branches
within parotid :
-Temporal
-Zygomatic
-Buccal
-Marginal Mandibular
-Cervical
46. CHORDA TYMPANI:
Carries taste from anterior 2/3rd of the
tongue and parasympathetic innervations to all salivary
glands below the level of oral tissues.
Originates from facial nerve
Enters lateral aspect of middle ear
Leaves middle ear
Enters infratemporal fossa
Descends to join lingual nerve after 2cm below the skull
47. Extracranial course/ 7th nerve
Emerges from the base of the skull at stylomastoid
foramen and gives off nerve as posterior auricular
branch(back of ear) and supplies auricular muscle and
fronto-occipital muscle.
Posteriorly another branch to Anterior Belly of Digastric
& Stylohyoid.
Nerve then enters the parotid & within the gland
branches into Temporofacial & Cervicofacial branches.
The trunks branch further to form a Parotid Plexus.
5 terminal branches arise from the plexus , diverge &
supply the muscles of facial expression.
-Temporal -Zygomatic
-Buccal -Marginal mandibular
-Cervival
48. Ganglia associated with facial nerve
1) Geniculate ganglion:
sensory ganglion.
not a para symphathetic ganglion
as it has cell bodies of sensory
neurons.
After reaching here ,Salivatory fibres
into middle ear followed by ending
up in submandibular ganglion ,
whereas the Lacrimatory fibres go
to middle cranial fossa & enter
foramen lacerum to enter
Pterygopalatine Fossa
49. 2) Submandibular ganglion:
-parasympathetic
-relay of secretomotor
fibers to submandibular and
sublingual glands
3) Pterygopalatine ganglion:
-parasympathetic
-secretomotor fibers are relayed to
lacrimal gland.
50. Within Facial Canal & Stylomastoid Foramen
Nerve to stapedius : supplies the
stapedius muscle.
Chorda Tympani : enters the
middle ear and joins the lingual
nerve
Posterior auricular : arises below
the stylomastoid foramen &
supplies the a) orbicularis posterior
b) occipitalis c) intrinsic muscles
back of auricle.
Digastric Branch : supplies the
Post. Belly of Digastric.
Stylohyoid Branch : arises with
the digastric & supplies the
stylohyoid.
51. THE TERMINAL BRANCHES
Temporalis branch : crosses the
zygomatic arch & supplies the
Frontalis , Orbicularis Oculi ,
Corrugator Supercilii , Auricularis Sup.
& Anterior
Zygomatic : runs across the zygomatic
bone & Supplies the Orbicularis Oculi
Buccal Branch : above & below the
Parotid supplying the Buccinator.
Marginal Mandibular : runs deep to
the platysma & supplies muscles of
lower lip & chin.
Cervical : emerges from the apex of
parotid & supplies the platysma.
52. Applied anatomy of facial nerve
Infranuclear lesions: ex-
Bells palsy (at stylomastoid
foramen),upper and lower
quarters of face on same side
gets paralysed.
Supranuclear lesions: only
the lower quarter of opposite
side of face is paralysed
Crocodile tears : in proximal
part of nervous intermedius
some regenerating salivary
fibers find their way into
greater petrosal nerve
53. Acute crocodile tear syndrome without antecedent facial nerve palsy
Chi Yun Doreen Ho MBBS ,Thomas G Hardy FRANZCO
First published: 14 February 2018
The case of a 47-year-old male with an unremarkable past medical and ocular history who sustained
a motor vehicle accident in 1995 resulting in partial amputation of his left pinna that required partial
pinnectomy in 2000. In October 2013, he underwent residual left pinnectomy and implantation of
three osseointegrated implants for prosthetic ear reconstruction. These were uncovered in a second-
stage procedure in July 2014. Three weeks after the second-stage procedure, he described new left-
sided symptoms of otalgia, hearing loss and lacrimation stimulated only when eating. At no stage was
there any history or clinical evidence of facial weakness.
(a) Crocodile tear syndrome (CTS) with antecedent facial nerve palsy. Misdirection of regenerating
salivary fibres destined for the salivary glands become secretory fibres to the lacrimal gland thus
establishing a new reflex arc, causing ipsilateral tearing while the patient is eating. If the lesion is in
the facial nerve proximal to or involving the geniculate ganglion (explaining its association with an
antecedent facial nerve palsy) where the lacrimal and salivary fibres run together, abnormal
regeneration of gustatory fibres occurs through the greater superficial petrosal nerve to reach the
lacrimal gland. (b) CTS without antecedent facial nerve palsy. Misdirection of regenerating salivary
fibres of glossopharyngeal nerve where tympanic branch divides into tympanic plexus to aberrantly
reinnervate the sphenopalatine ganglion and thus stimulate the lacrimal gland.
54. BELLS PALSY & FACIAL PARALYSIS
A syndrome that consisted of
ipsilateral facial paralysis with intact
facial sensation that occurred after the
transection of facial nerve.
Etiology: Ischemia, edema and
compression of the nerve.
- Central lesion
- Infra nuclear lesion
- Lesion around geniculate
ganglion
- Lesion at or around stylomastoid
foramen
55. Treatment :
Proper care of the eye
-eyedrops/artificial tears
- ointment at bed time
-goggles for dust protection
Steroids
Antiviral agents
Alcohol injections
Physiotherapy
Clinical Features :
Lesion unilateral
Unable to laugh/ smile
Cannot blink his eyes
Unable to raise eyebrows
Absence of wrinkles on forehead
Corner of mouth droops
Infection of eye
57. GLOSSOPHARYNGEAL NERVE
Nerve of the 3rd Brachial arch.
It is the 9th cranial nerve.
Mixed nerve
Exit from skull: jugular foramen.
functions:
Secretomotor to parotid gland
Gustatory to post. 1/3rd of tongue
Motor to stylopharyngeus
Sensory to pharynx, tonsil, post. 1/3rd of tongue.
NUCLEI PRESENT :
1. Nucleus Ambigius : Brachiomotor
2. Inf. Salivatory : Parasymphathetic
3. Nucleus of Tractus Solitarius :
Gustatory
Functional components;
SVE : supply stylopharyngeus
GVE : supply parotid
GVA : supply the oro & laryngo
pharynx
SVA : from post. 1/3rd of tongue.
58. Course of 9th nerve
Intracranial:
-Arises from the upper part of the lateral aspect of medulla by 3-4
rootlets
-Filaments unite to form a single trunk , passes lateraly to leave
cranial cavity through jugular foramen
-superior and inferior sensory ganglia are located on the nerve as it
passes through jugular foramen
-inferior ganglion contains most of the sensory fibers.
59. Extra cranial:
-Descends between Internal Jugular Vein & Internal Carotid
Artery
-Pass toward the lateral aspect of stylopharyngeous
-Pass between external & internal carotid arteries reaches side
of pharynx
-Then curves along the lateral aspect of stylopharyngeus muscle
deep to stylohyoid ligament and gives terminal branches
60. Ganglion associated with Glossopharyngeal
nerve & it’s Connections ‘OTIC’
• Peripheral parasympathetic
• Relays secretomotor fibers to parotid
gland
• Situated in infratemporal fossa
• Motor root formed by lesser petrosal nerve
• Sympathetic root by plexus around
middle meningeal artery
• Sensory root from auriculotemporal nerve
61. 1.Tymphanic Nerve : takes part in the formation of
tympanic plexus
1 branch of PLEXUS is called Lesser
Petrosal Nerve.
2. Carotid Branch : supplies the Carotid Sinus &
the Carotid Body.
3. Pharyngeal Branch : takes part in forming the
pharyngeal plexus.
4. Muscular Branch : Supplies the
Stylopharyngeus.
5 Tosillar Branches : supplies the tonsils , joins
the plexus with lesser palatine.
6. Lingual Branch : Carry Taste & General
sensation from the post. 1/3rd of the tongue.
Branches of 9th nerve
62. Applied anatomy/ 9th nerve
Glossopharyngeal neuralgia:
Rare condition – paroxysmal pain i.e
similar to trigeminal neuralgia.pain in ear,throat
and neck
Cause: oropharyngeal tumors,stylohyoid
ligament ossifications,multiple sclerosis.
Types: 1.classic/episodic pain
2.symptomatic/continuos pain
Trigger zones: pharynx, post. 1/3rd of tongue,
ear & infra auricular areas.
Treatment: similar to trigeminal neuralgia
-anticonvulsant drugs
-NSAIDS
-Surgical procedures(rhizotomy)
63. Orofacial neuralgia associated with a middle cerebral artery aneurysm
Raoul Julio Mascarenhas ,Narada Dhitimantha Hapangama ,Peter James Mews ,Arjun Burlakoti,Sarbin Ranjitkar First published: 07
December 2018
Case report A 62-year-old female patient presented for a general dental examination with a
chief concern of mild pain around the right mandible. Dental history revealed nocturnal bruxism,
for which the patient had been wearing an occlusal splint for 20 years.The masseter and
temporalis muscles as well as the lateral pole of the right mandibular condyle were tender to
palpation. There was no clicking or significant deviation or limitation to mandibular opening,
closing and lateral movements. Furthermore, multiple carious teeth and failing restorations were
identified, for which a management plan was formulated. The patient was counselled with
regards to the role of bruxism in the aetiology of facial pain, and her symptoms were monitored
over the course of restorative care. Three months after the initial appointment, the pattern and
severity of the pain changed. The pain became moderately intense and stabbing in nature. It
was precipitated by swallowing, and radiated through the right throat, posterior border of the
mandible, ear and temporomandibular joint (TMJ)Generally, differential diagnoses of chronic
facial pain (in decreasing order of occurrence) include odontogenic pain, temporomandibular
joint disorders, temporal arteritis, cranial nerve neuropathies, salivary gland pathology, and
Eagle’s Syndrome. subsequently an MRI scan of the head was obtained, which revealed a 7
mm × 6 mm aneurysm in the M2 segment of the Middle cranial artery (MCA). Differentiating
between TMD and other causes of facial pain can be a diagnostic challenge. It is the first case
of orofacial pain that was relieved by surgical clipping of an Middle cranial artery aneurysm.
65. THE CERVICAL PLEXUS
Formed by the ventral rami of the upper 4
cervical nerves C1 – C4 with contribution
Of C5.
The plexus is related posteriorly to the
muscles that arise from the posterior
tubercle Of the transverse process i.e. the
Levator Scapulae and scalenus medius
Anteriorly, to the prevertebral fascia, the
Internal jugular vein and the
sternocleidomastoid.
The four roots forming the plexus connect to
each other to form three loops. E.g. C1-C2,
C2-C3, C3-C4.
66. Branches
1. Communicating branches:
a. Grey rami pass from superior cervical ganglion to the
roots of C1-4 nerves.
b. Branch from C1 that joins the hypoglossal nerve
c. Branch from C2 to sternocleidomastoid and
d. Branches from C3 and 4 to the spinal accessory nerve
which supplies the trapezius muscle
67. 2. Superficial (sensory) branches, which supply cutaneous fibers
to the neck.
a. Ascending branches; Lesser occipital (C2) and Greater
auricular (C2,3)
b. Transverse branch; Transverse (anterior) cutaneous nerve of
the neck (C2,3)
c. Descending branches; Supraclavicular (C3,4)
3. Deep branches, to the neck muscles.
4.The phrenic nerve, which is the motor nerve of the diaphragm.
5.Motor branches
69. REFERENCES
GRAY’S anatomy for students (third edition)
Anatomy of head neck and brain by VISHRAM SINGH
Human anatomy-head and neck by B.D CHAURASIA
Internet sources