Mitochondria are membrane-bound organelles found in eukaryotic cells that generate most of a cell's supply of ATP, which is used as a source of chemical energy. They have two membranes and a matrix inside. Mitochondria were first observed in the 1840s and named in 1898. They range in size from 0.5 to 1.0 micrometers and can vary widely in number per cell. Mitochondria contain enzymes that combine food molecules with oxygen to digest the materials and produce energy for the cell. Mitochondrial dysfunction has been linked to several human diseases.