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LIVER INJURY
Dr. Haseeb Manzoor
Department Of Radiology
SMCH, Lahore
LIVER INJURY
 2nd most commonly injured organ in abdominal trauma after spleen
 Highest mortality rate in abdominal injury ~4.1% to 11.7%
 mortality rate is higher with blunt trauma than with penetrating
trauma
 Right lobe more commonly injured than left
AETIOLOGY
 Blunt trauma (e.g. motor vehicle collision, fall, direct blow)
 Penetrating trauma (e.g. gunshot, stabbing)
 Iatrogenic (e.g. percutaneous liver biopsy)
ASSOCIATIONS
 bile duct injuries
 right kidney injury
 Adrenal haemorrhage
 Hemoperitoneum
 Retroperitoneal haematoma
 right lower lobe pulmonary contusion/laceration
 haemo/pneumothorax
 right sided rib fractures
 transverse process fractures
COMPLICATIONS
 bile duct injury leading to bile peritonitis or biloma
 delayed haemorrhage
 Hepatic or perihepatic abscess
 acute acalculous cholecystitis
CLINICAL PRESENTATION
 related to the amount of blood loss
 right upper quadrant pain
 right shoulder tip pain (from diaphragmatic irritation)
 hypotension and shock
LABS
Elevated liver transaminases (ALT/AST) ~100% specific and ~93%
sensitive.
ULTRASONOGRAPHY
 FAST is readily available & most commonly perfomed investigation.
 It can demonstrate hematomas, contusions, bilomas, and
hemoperitoneum.
62-year-old woman with a history of recent liver biopsy.
a loculated anechoic collection in the liver.
35-year-old male, after sustaining blunt abdominal injury
a crescent-shaped hypoechoic collection along the right lateral aspect
of the liver - subcapsular hematoma
50 yrs , Male
48 hrs follow up after RTA
Heterogeneous echopattern area in right lobe of liver - contusion.
Enlarged right adrenal gland. Right kidney is normal.
PLAIN RADIOGRAPH
Non-specific
Associated injuries can be evaluated i.e
 Ribs / vertebral fractures
 Pneumoperitoneum
 major diaphragmatic injury
 gross organ displacement
 metallic foreign bodies
N.B
Suspect liver injury in case of Right lower ribs fracture.
COMPUTED TOMOGRAPHY
 Contrast enhancedCT is gold standard
 ~95% sensitive and 99% specific
 Grading of liver injury is based on CT findings
 AAST grading is most widely accepted
LACERATION:
Irregular linear/branching areas of hypoattenuation
ACTIVE BLEEDING:
Contrast extravasation
SUBCAPSULAR HAEMATOMA:
Hypodense elliptical collection between the liver and its capsule
(indents the liver surface)
INTRAPARENCHYMAL HAEMATOMA (CONTUSION):
focal, ill-defined low density areas within the liver parenchyma on
contrast enhancedCT,
or a high density (40-60 HU) area on unenhancedCT
17 yrs, Male , Fell from bike
C+ portal venous phase CT abdomen
"bear claw" laceration of the right hepatic lobe
Contrast-enhancedCT
multiple subcapsular hematomas in the right and left lobes (arrows).
Multifocal intraparenchymal hematomas (arrowheads).
PITFALLS
 On a contrast enhancedCT, a fatty liver may become isoattenuating
to the laceration / hematoma.
 Focal fatty infiltration may mimic hepatic hematoma, laceration, or
infarction.
 Hepatic lacerations with a branching pattern can mimic unopacified
portal or hepatic veins or dilated intrahepatic bile ducts.
 Beam hardening artifact due to adjacent rib, mimics laceration
LIVER INJURY SCALE
Proposed by Mirvis et al (1994)
GRADE HEMATOMA
(CENTRAL/SUBCAPSULAR)
LACERATION
1 < 1 CMTHICK
ISOLATED PERIPORTAL BLOOD
TRACKING
CAPSULAR AVULSION
LACERATION <1 CM DEEP
2 < 3 CM <3 CM DEEP,
3 > 3 CM >3 CM DEEP,
4 > 10 CM LOBARTISSUE DESTRUCTION (MACERATION)
OR DEVASCULARISATION
5 BILOBARTISSUE DESTRUCTION (MACERATION)
OR DEVASCULARISATION
Proposed by AAST (AmericanAssociation ForThe Surgery OfTrauma)
GRADE HEMATOMA
Sub-capsular Intra-parenchymal
LACERATION
1 <10% surface area - <1 cm parenchymal depth
2 ≤50% surface area <10 cm in diameter ≤3 cm parenchymal depth
3 >50% surface area >10 cm in diameter >3 cm parenchymal depth
4 Expanding / ruptured hematoma with
active bleeding
Parenchymal disruption of ≤75% of A
lobe/
≤3 couinaud segments within A lobe
VASCULAR INJURY
5 Juxtahepatic venous injuries
I.E retrohepatic ivc or central major
hepatic veins
Parenchymal disruption of >75% of A
lobe/
>3 couinaud segments within A lobe
6 Hepatic avulsion -
Grade 1 liver injury: 21 years , Female
subcapsular haematoma in segment 7
< 10% of surface area, < 1 cm deep
Grade 2 liver injury:
Laceration (< 3 cm deep) in the posterior right hepatic lobe (arrow)
A small fluid collection in the hepatorenal fossa (arrowheads)
Grade 3 liver injury: 8 years , Male
Multiple lacerations in right hepatic lobe, >3 cm deep.
Large subcapsular hematoma. no active contrast extravasation
Grade 4 liver injury: 35 years, Male
Large laceration in the right lobe of the liver with a perihepatic
haematoma. Active contrast extravastation into the perihepatic space
Grade 5 liver injury: 45 years, Male
Liver laceration with involvement of the left hepatic vein, left portal vein
and possibly the IVC. Contrast pooling around the IVC. Large volume
haemoperitoneum.
MAGNETIC RESONANCE IMAGING
 limited role
 no advantage over CT scanning
 may be used in follow-up monitoring
 may be used in pregnant women
MRCP can be used for assessment of pancreatic duct / biliary trauma
and its sequelae.
ANGIOGRAPHY
 No role in evaluation of unstable patients.
 Demonstrates the site of active bleeding.
 Provides opportunity for transcatheter embolization, which may be
the only treatment required.
Selective celiac arteriogram
21 yrs old, male
stabbing injury to the right
upper quadrant
a focal area of hemorrhage in
the right lobe (arrow).
filling defect in the lateral
aspect of the right lobe of
liver due to compression of
liver parenchyma by
subcapsular hematoma.
Celiac arteriogram shows contrast extravasation from a branch of the
right hepatic artery (arrow).
Post-embolization angiogram shows embolized microcoils (arrows) and
no further extravasation.
MANAGEMENT
 Based on clinical and haemodynamic status of the patient
 unstable haemodynamic status is an Indication for open surgical
intervention
Grade I-II injuries are considered minor
usually require minimal or non operative treatment
Grade III-V injuries are considered severe
usually require surgical intervention
gradeVI injuries are regarded as incompatible with survival
Non operative management
If patient is haemodynamically stable
Liver Embolization
If patient is haemodynamically stable/ Low grade liver injury
For controlling active arterial haemorrhage
Damage control surgery
If patient is haemodynamically unstable
Suspicion of Hepatic venous injuries
Abdominal trauma/
Suspicion of liver injury
Hemodynamically stable
radiological investigations
No active bleeding
Manage
conservatively
small arterial bleeding
Transcatheter
embolization
Hemodynamically unstable
surgery
REFERENCES
http://pubs.rsna.org/doi/full/10.1148/rg.251045079
http://emedicine.medscape.com/article/370508-overview
https://radiopaedia.org/articles/liver-trauma
http://www.aast.org/Library/TraumaTools/InjuryScoringScales.aspx#liver
http://www.radiologyassistant.nl/en/p466181ff61073/acute-abdomen-role-of-ct-in-trauma.html

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liver injury

  • 1. LIVER INJURY Dr. Haseeb Manzoor Department Of Radiology SMCH, Lahore
  • 2. LIVER INJURY  2nd most commonly injured organ in abdominal trauma after spleen  Highest mortality rate in abdominal injury ~4.1% to 11.7%  mortality rate is higher with blunt trauma than with penetrating trauma  Right lobe more commonly injured than left
  • 3. AETIOLOGY  Blunt trauma (e.g. motor vehicle collision, fall, direct blow)  Penetrating trauma (e.g. gunshot, stabbing)  Iatrogenic (e.g. percutaneous liver biopsy)
  • 4. ASSOCIATIONS  bile duct injuries  right kidney injury  Adrenal haemorrhage  Hemoperitoneum  Retroperitoneal haematoma  right lower lobe pulmonary contusion/laceration  haemo/pneumothorax  right sided rib fractures  transverse process fractures
  • 5. COMPLICATIONS  bile duct injury leading to bile peritonitis or biloma  delayed haemorrhage  Hepatic or perihepatic abscess  acute acalculous cholecystitis
  • 6. CLINICAL PRESENTATION  related to the amount of blood loss  right upper quadrant pain  right shoulder tip pain (from diaphragmatic irritation)  hypotension and shock
  • 7. LABS Elevated liver transaminases (ALT/AST) ~100% specific and ~93% sensitive.
  • 8. ULTRASONOGRAPHY  FAST is readily available & most commonly perfomed investigation.  It can demonstrate hematomas, contusions, bilomas, and hemoperitoneum.
  • 9. 62-year-old woman with a history of recent liver biopsy. a loculated anechoic collection in the liver.
  • 10. 35-year-old male, after sustaining blunt abdominal injury a crescent-shaped hypoechoic collection along the right lateral aspect of the liver - subcapsular hematoma
  • 11. 50 yrs , Male 48 hrs follow up after RTA Heterogeneous echopattern area in right lobe of liver - contusion. Enlarged right adrenal gland. Right kidney is normal.
  • 12. PLAIN RADIOGRAPH Non-specific Associated injuries can be evaluated i.e  Ribs / vertebral fractures  Pneumoperitoneum  major diaphragmatic injury  gross organ displacement  metallic foreign bodies
  • 13. N.B Suspect liver injury in case of Right lower ribs fracture.
  • 14. COMPUTED TOMOGRAPHY  Contrast enhancedCT is gold standard  ~95% sensitive and 99% specific  Grading of liver injury is based on CT findings  AAST grading is most widely accepted
  • 15. LACERATION: Irregular linear/branching areas of hypoattenuation ACTIVE BLEEDING: Contrast extravasation
  • 16. SUBCAPSULAR HAEMATOMA: Hypodense elliptical collection between the liver and its capsule (indents the liver surface) INTRAPARENCHYMAL HAEMATOMA (CONTUSION): focal, ill-defined low density areas within the liver parenchyma on contrast enhancedCT, or a high density (40-60 HU) area on unenhancedCT
  • 17. 17 yrs, Male , Fell from bike C+ portal venous phase CT abdomen "bear claw" laceration of the right hepatic lobe
  • 18. Contrast-enhancedCT multiple subcapsular hematomas in the right and left lobes (arrows). Multifocal intraparenchymal hematomas (arrowheads).
  • 19. PITFALLS  On a contrast enhancedCT, a fatty liver may become isoattenuating to the laceration / hematoma.  Focal fatty infiltration may mimic hepatic hematoma, laceration, or infarction.  Hepatic lacerations with a branching pattern can mimic unopacified portal or hepatic veins or dilated intrahepatic bile ducts.  Beam hardening artifact due to adjacent rib, mimics laceration
  • 21. Proposed by Mirvis et al (1994) GRADE HEMATOMA (CENTRAL/SUBCAPSULAR) LACERATION 1 < 1 CMTHICK ISOLATED PERIPORTAL BLOOD TRACKING CAPSULAR AVULSION LACERATION <1 CM DEEP 2 < 3 CM <3 CM DEEP, 3 > 3 CM >3 CM DEEP, 4 > 10 CM LOBARTISSUE DESTRUCTION (MACERATION) OR DEVASCULARISATION 5 BILOBARTISSUE DESTRUCTION (MACERATION) OR DEVASCULARISATION
  • 22. Proposed by AAST (AmericanAssociation ForThe Surgery OfTrauma) GRADE HEMATOMA Sub-capsular Intra-parenchymal LACERATION 1 <10% surface area - <1 cm parenchymal depth 2 ≤50% surface area <10 cm in diameter ≤3 cm parenchymal depth 3 >50% surface area >10 cm in diameter >3 cm parenchymal depth 4 Expanding / ruptured hematoma with active bleeding Parenchymal disruption of ≤75% of A lobe/ ≤3 couinaud segments within A lobe VASCULAR INJURY 5 Juxtahepatic venous injuries I.E retrohepatic ivc or central major hepatic veins Parenchymal disruption of >75% of A lobe/ >3 couinaud segments within A lobe 6 Hepatic avulsion -
  • 23. Grade 1 liver injury: 21 years , Female subcapsular haematoma in segment 7 < 10% of surface area, < 1 cm deep
  • 24. Grade 2 liver injury: Laceration (< 3 cm deep) in the posterior right hepatic lobe (arrow) A small fluid collection in the hepatorenal fossa (arrowheads)
  • 25. Grade 3 liver injury: 8 years , Male Multiple lacerations in right hepatic lobe, >3 cm deep. Large subcapsular hematoma. no active contrast extravasation
  • 26. Grade 4 liver injury: 35 years, Male Large laceration in the right lobe of the liver with a perihepatic haematoma. Active contrast extravastation into the perihepatic space
  • 27. Grade 5 liver injury: 45 years, Male Liver laceration with involvement of the left hepatic vein, left portal vein and possibly the IVC. Contrast pooling around the IVC. Large volume haemoperitoneum.
  • 28. MAGNETIC RESONANCE IMAGING  limited role  no advantage over CT scanning  may be used in follow-up monitoring  may be used in pregnant women MRCP can be used for assessment of pancreatic duct / biliary trauma and its sequelae.
  • 29. ANGIOGRAPHY  No role in evaluation of unstable patients.  Demonstrates the site of active bleeding.  Provides opportunity for transcatheter embolization, which may be the only treatment required.
  • 30. Selective celiac arteriogram 21 yrs old, male stabbing injury to the right upper quadrant a focal area of hemorrhage in the right lobe (arrow). filling defect in the lateral aspect of the right lobe of liver due to compression of liver parenchyma by subcapsular hematoma.
  • 31. Celiac arteriogram shows contrast extravasation from a branch of the right hepatic artery (arrow). Post-embolization angiogram shows embolized microcoils (arrows) and no further extravasation.
  • 32. MANAGEMENT  Based on clinical and haemodynamic status of the patient  unstable haemodynamic status is an Indication for open surgical intervention Grade I-II injuries are considered minor usually require minimal or non operative treatment Grade III-V injuries are considered severe usually require surgical intervention gradeVI injuries are regarded as incompatible with survival
  • 33. Non operative management If patient is haemodynamically stable Liver Embolization If patient is haemodynamically stable/ Low grade liver injury For controlling active arterial haemorrhage Damage control surgery If patient is haemodynamically unstable Suspicion of Hepatic venous injuries
  • 34. Abdominal trauma/ Suspicion of liver injury Hemodynamically stable radiological investigations No active bleeding Manage conservatively small arterial bleeding Transcatheter embolization Hemodynamically unstable surgery