This document provides an overview of hydronephrosis, including definitions, etiology, pathophysiology, clinical features, investigations, and management. Hydronephrosis is dilation of the renal pelvis or calyces that can be associated with obstruction. The causes include congenital issues like PUJ obstruction or acquired issues like ureteral strictures. Untreated obstruction can lead to renal damage through stages of compensation and decompensation. Clinical features depend on the cause but may include loin or groin pain. Investigations include imaging like ultrasound, IVU, CT scan, and urodynamics. Management involves relieving obstruction through surgery or stenting as well as treating infections.
POSTERIOR URETHRAL VALVES- Pediatric Surgery
• Dear viewers,
• Greetings from “ Surgical Educator”
• Today I have uploaded one more video in Pediatric Surgery/Pediatric Urology- “ Posterior Urethral Valves”
• Posterior Urethral Valves is the congenital cause for Bladder Outlet Obstruction, resulting in abnormal development of the kidneys as well as the bladder.
• In this video, I talked about the learning outcomes, introduction, etiopathogenesis, clinical features, investigations, differential diagnosis, treatment, follow-up and prognosis of “ Posterior Urethral Valves”
• I hope you will enjoy the video for its educational value.
• You can watch all my teaching videos in the following links
• surgicaleducator.blogspot.com youtube.com/c/surgicaleducator
• Thank you for watching the video.
The urethra's main job in males and females is to pass urine outside the body. This thin tube also has an important role in ejaculation for men. When a scar from swelling, injury or infection blocks or slows the flow of urine in this tube, it is called a urethral stricture. Some people feel pain with a urethral stricture.
Please find the power point on Renal and bladder stones. I tried present it on understandable way and all the contents are reviewed by experts and from very reliable references. Thank you
POSTERIOR URETHRAL VALVES- Pediatric Surgery
• Dear viewers,
• Greetings from “ Surgical Educator”
• Today I have uploaded one more video in Pediatric Surgery/Pediatric Urology- “ Posterior Urethral Valves”
• Posterior Urethral Valves is the congenital cause for Bladder Outlet Obstruction, resulting in abnormal development of the kidneys as well as the bladder.
• In this video, I talked about the learning outcomes, introduction, etiopathogenesis, clinical features, investigations, differential diagnosis, treatment, follow-up and prognosis of “ Posterior Urethral Valves”
• I hope you will enjoy the video for its educational value.
• You can watch all my teaching videos in the following links
• surgicaleducator.blogspot.com youtube.com/c/surgicaleducator
• Thank you for watching the video.
The urethra's main job in males and females is to pass urine outside the body. This thin tube also has an important role in ejaculation for men. When a scar from swelling, injury or infection blocks or slows the flow of urine in this tube, it is called a urethral stricture. Some people feel pain with a urethral stricture.
Please find the power point on Renal and bladder stones. I tried present it on understandable way and all the contents are reviewed by experts and from very reliable references. Thank you
BENIGN PROSTATE HYPERPLASIA (BPH)
AETIOLOGY
It is benign enlargement of prostate which occurs after 50 years, usually between 60 and 70 years.
BPH affects both glandular epithelium and connective tissue stroma.
It is involuntary hyperplasia due to disturbance of the ratio and quantity of circulating androgens and estrogens.
PATHOLOGY OF URINARY SYSTEM DISORDER pptSaili Gaude
This lecture includes pathology of renal calculi , renal carcinoma, bladder carcinoma, bladder tumor, renal tumor etc. This lecture have been prepared in view of Nursing students according to syllabus.
Please find the power point on Gastric Outlet Obstruction. I tried present it on understandable way and all the contents are reviewed by experts and from very reliable references. Thank you
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
3. Definitions
• Hydronephrosis is the dilation of the renal pelvis or calyces. It
may be associated with obstruction but may be present in the
absence of obstruction.
• Obstructive uropathy refers to the functional or anatomic
obstruction of urinary flow at any level of the urinary tract.
• Obstructive nephropathy is present when the obstruction causes
functional or anatomic renal damage.
6. PUJ Obstruction
• MC congenital abnormality of ureter
• F > M, Left > Right
• Mechanism not clear
• True stenosis is rare; Angulation, kink, high origin of ureter,
hypoplastic ureter etc., are observed
• Abnormal peristalsis interfering with urine flow
7.
8. VUJ abnormalities
• Obstruction may be similar to PUJ
• Many other structural abnormalities are also noted
- Distal ureteral stenosis
- Ectopic insertion of ureter
- Ureterocoele
- Duplication of ureters
9. Posterior Urethral Valve
• MC urethral obstructive lesions in newborn males
• MC cause of bilateral hydronephrosis in male fetuses
• Seen in distal prostatic urethra
• Thin membranous folds causing obstruction to unine outflow
• First described by Young
• Assosciated with other congenital abnormalities - Pulmonary
hypoplasia
15. VUR
• Intravesical ureter and Bladder trigone act as valve at VUJ and
prevent reflux of vesical urine into ureter
• Any condition that effects - length of intra vesical ureter and tone of
trigone results in deficient valvular function
• High vesical pressures are transmitted into the ureter
• VUR results in Increased workload, High hydrostatic pressure, Weak
ureter musculature
16. VUR may be caused by
•Congenital weakness of Trigone
•Voiding dysfunction
•Vesical trabeculation
•Edema of vesical wall secondary to cystitis
17. Neurogenic bladder
• Caused due to lesions along micturition reflex pathway
• Lesions above sacral micturition centre (UMN lesion) - Overactive
bladder with Dyssenrgia
• Overactive bladder with sphincter dyssynergia results in High voiding
pressures, detrusor hypertrophy, VUR / VUJ obstruction
• If lesion is above Pontine micturition centre, detrusor sphincter
dyssnergia doesnot occur
18. • Lesions at or below sacral micturition centre lead to Flaccid
neuropathic bladder
• Injury to motor nuclei may occur in polio myelitis, herpes zoster, disc
herniation or Cauda equina syndrome
• Injury to afferent pathways result in loss of sensation from bladder
• Seen in Diabetes, Tabes dorsalis and other posterior cord lesions
19. Spastic Neuropathic Bladder
• Reduced capacity
• Involuntary Detrussor
Contractions
• High voiding pressures
• Marked hypertrophy of bladder
wall
• Spastic external sphincter
Flacid Neuropathic Bladder
• Large capacity
• Lack of voluntary detrussor
contraction
• Low intravesical pressures
• Mild hypertrophy of bladder
• Decreased tone of external
sphincter
21. Stage of Compensation
• Due to increase in resistance to urine flow in the ureter, there is
gradual dilation of ureter and pelvis
• Compensatory hypertrophy occurs and increase in peristaltic activity
occurs resulting in ureter becoming elongated and tortuous
• Secondary fibrous bands may develop resulting in secondary
obstruction
22. Stage of Decompensation
• As the pressure increases, ureter continues to stretch, it’s wall
becomes weak and attenuated, loses its contractile power
• Some times ureter may be so extremely dilated that it may resemble
a loop of bowel
25. Renal changes
• Higher the obstruction earlier and greater are the effects on kidney
• As pressure rises initially the pelvis and calyces dilate
• Pelvis may be intra renal or extra renal
• Earlier stages compensatory hypertrophy happens in pelvis
musculature but later it becomes stretched and atonic
26. • Finally, Compression atrophy and ischemic atrophy occur
• Results in spotty atrophy early on, in advanced stages parenchyma is
thinned out
• In unilateral obstruction these changes are relatively faster as
opposite kidney is functioning and it’s function increases to
compensate for the loss of function in one kidney
• In bilateral obstruction these changes are slow as kidneys attempt to
maintain renal function
27. • Kidney doesnot exhibit typical response to obstruction and increased
pressure; whereas other glands cease to secrete , kidney continues to
secrete urine
• In the pelvis, water and solutes are reabsorbed via lymphatics
gradually relieving the pressure
• There may be a break in dilated pelvis resulting in extravasation of
urine into renal parenchyma decompressing the pelvis -
Pyelointerstitial back flow
28. Mid tract / Bladder
• Stage of irritable or hypersensitive bladder
• Stage of compensation
• Stage of decompensation
29. Stage of irritability
• Occurs in the very initial phases when compensatory hypertrophy
begins, when the detrusor is hypersensitive
• As urine accumulates the urge to micturate cannot be controlled as
the detrusor contraction is so strong it almost goes into a spasm
• Hence first features of BOO are usually Urgency and Frequency
• Can sometimes be severe enough to mimic incontinence
30. Stage of Compensation
• As the obstruction increases, hypertrophy increases and pressure
required to initiate micturition also increases
• Patient notices Hesitancy to micturate as the bladder needs to
overcome the resistance and generate contraction powerful enough
to initiate micturition
• However the bladder empties completely and no residual urine is
noted in this phase
31. • Compensatory hypertrophy results in trabeculation of the bladder
• Trigonal area also hypertrophies narrowing ureteric orifices and
thereby resulting in upper tract obstruction
• As intra vesical pressures increase the bladder mucosa in between
trabeculae pouches out to form diverticulae
32. Stage of Decompensation
• Resistance exceeds the detrusor power, signalled by appearance of
post void residual urine in the bladder
• Can be acute or chronic
• As the volume of residual urine increases the intra vescical pressures
increase simultaneously stretching detrussor resulting in reflux of
urine and transmission of high intra vescical pressures into upper
tract.
33. • Acute decompensation occurs when muscle tone is impaired due to
rapid filling of bladder or over stretching the detrussor
• Presents as high frequency, very poor stream and low volume voided
in spite of straining with large post void residual urine
• Some times can present as sudden acute retention of urine
34. • Chronic decompensation occurs as a result of progressive imbalance
between voiding power and resistance to urine flow
• Symptoms of obstruction increase gradually and becomes
increasingly difficult to empty the bladder
• Residual urine increases gradually which stretches the bladder which
loses it’s power, dilates to hold 1000-3000 ml urine
• VUR develops due to weakness of trigone and high intravesical
pressure
• Finally Overflow incontinence results
35.
36. Lower Tract
• Pathogenesis is similar to bladder outlet obstruction
• In addition, urethra may be dilated and prostatic ducts may also be
dilated
• Diverticulae may be formed and urine infected resulting in
periurethral abscess
37.
38. Clinical features
• Clinical features are widely variable and mostly depend on cause of
obstruction
• Hydronephrosis per se can be asymptomatic
• Upper tract symptoms are effectively those of ureteric calculus /
stricture
• Pt complains of Loin to groin pain may be accompanied by burning
micturition, colicky pain, vomitings etc
• Bilateral obstruction results in decreased urine output and pt may
end up in uremia
39. Intermittent obstruction
•Also known as Dietls crisis
•Pt suddenly develops symptoms of upper tract obstruction - pain in
loin, palpable swelling at renal angle especially after intake of fluids
•The symptoms are relieved after sometime with passage of large
amounts of urine
•Could be due to slipping down of ureteric calculus
40. • Features of Mid tract obstruction are usually those of BOO i.e., LUTS
• Decompensated patients may present with acute urinary retention or
overflow incontinence
• In case of Ca Prostate or Bladder mass causing BOO, there may be
painless hematuria, loss of weight may be present
• In case of lower tract obstruction, pt presents with difficulty in
micturition with features of recurrent uti
42. Plain X ray KUB can give information regarding
•Renal shadow
•Radio opaque calculi
•Any calcifications
43. IVU aka Excretory Urography is a contrast radiograph of KUB
•Iodine contrast medium is given intra venously
•scout images
•nephrogram (1-2 minutes)
•early and late images of the upper collecting system (>3 minutes)
•supine images of the upper collecting system and proximal ureters
(10-15 minutes)
•Erect films may be taken for ureters
•Post void film
44. Retrograde Urography
•Rarely used after advent of ct scan
•Can be done if IVU and CT fail to visualise ureteral segment
•Involves ureteroscopy, hence access for simultaneous biopsy or
intervention is available
45. Retrograde Cystourethrography
•Useful in cases of lower tract obstruction
•Especially helpful to visualise anterior urethra
MCUG
•Done to study bladder, posterior urethra and competence of VUJ
•Film is taken during micturition / when the pt is attempting to void
48. USG
•Widely used as it is non invasive and helps in identification of wide
variety of conditions
•Helps to establish dilatation of PCS
•Can visualise renal / upper ureteric calculi
•Can visualise any gross structural abnormalities
•Mainstay in prenatal imaging, hence useful for diagnosis of Antenatal
Hydronephrosis
51. CT scan
•Confirmatory test for most urological pathologies
•Plain ct can visualise anatomy of the kidneys, collecting system,
bladder and urethra
•Contrast can be given antegrade or retrograde for CT urography
52. Urodynamic study
•Important role in lower tract obstruction, voiding difficulties,
Incontinence and Neuropathic bladder
•Proper interpretation of urodynamics can help us know about Bladder
capacity, Compliance, Bladder sensation, Contractility
•Combined with electromyography it also assesses functioning of
sphinter and pelvic floor muscles
•Videourodynamics is combination of classic urodynamic study with
fluroscopy
54. Treatment
• Treatment as such depends on cause of obstruction
• But main aims of treatment are
- Decompression of urinary tract
- Treating UTI
- Definitive treatment of cause
55. • In cases of mild to moderate cases of HUN, definitive treatment of
obstruction can be done which simultaneously relieves pressure
• But in case of severe HUN especially where renal function is effected,
urinary tract is decompressed immediately
- Foleys catheterisation
- Supra pubic cystostomy
- Ureteric stenting
- Percutaneous Nephrostomy
56. ANH
• In case of antenatal hydronephrosis, post natal follow up is advised
• Initial scan done with in 1st week
• Post natal scan done at 48hrs tends to under estimate HUN because
of physiological oliguria in newborn
• Follow up scan can be done after 4-6 weeks
• Postnatally neonates tend to develop VUR, hence if necessary MCUG
is done
57.
58. PUJ
• MC in such cases is PUJ obstruction
• Definitive treatment includes creation of a dependent, funnel shaped
PUJ of adequate caliber
• No single procedure is considered superior as there are large
differences encountered in anatomy of PUJ
- Dismembered pyeloplasty
- Foleys V-Y pyeloplasty
- Pelvis flap techniques
62. PUV
• In case of Posterior urethral valve, definitive treatment consists of
destruction of the membranes
• Most of the valve cases present with HUN at diagnosis (about 95%)
may / maynot have reflux
• After ablation of valve usually HUN and VUR resolve
• But bladder dysfunction fails to resolve progressing to overflow
incontinence - Valve Bladder Syndrome
63. • Immediate catheterisation and bladder drainage is first step in
management
• If child is stable, transurethral fulgration is done combined with
vesicostomy if necessary with antibiotic coverage
• In children with urosepsis; bladder drainage, Antibiotic coverage,
correction of fluid and electrolyte abnormalities is done initially
• Children with bladder dysfunction may need Timed voiding, anti
cholinergics, intermittent catheterisation, continuous nocturnal
bladder drainage
64. VUR
• In cases of VUR, lower grades can be managed with antibiotics to
control uti until reflux resolves or surgically corrected
• When using medical therapy alone, MCUG are repeated every 12-18
months
• Surgical repair is considered if VUR is assosciated with ureteric
anomalies or severe HUN, Pyelonephritis persists despite antibiotics,
Evidence of renal damage on urograms and if pt is not compliant
with medical treatment
65. • Surgical therapy includes
• Initial temporary urinary diversion - Urethral catheter / Cystostomy /
Ureterostomy / Nephrostomy
• Followed by definitive repair of uretero vesical junction
• Other procedures include
- Nephrectomy
- Heminephrectomy
- Ureteroureterostomy
66. Neuropathic Bladder
For a Spastic Neuropathic bladder,
•In patients with reasonable capacity, voiding training is given, to void
every 2-3 hrs
•In patients with markedly diminished functional capacity, available
options are
- Muscarinic antagonists
- Indwelling catheter
- Sacral rhizotomy
- Sphincterotomy
67. For a Flaccid neuropathic bladder,
•Bladder training
•Intermittent Clean Catheterization
•Parasympathomimetics - Bethanechol
•Surgical option is for enlarged prostate - TURP