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Infection Control
Dr. Ahmad Uzair Qureshi
What are the next 28 minutes about !
Knowledge
• Understand importance of Hand washing
• Principle of appropriate antibiotics
• Familiarity with local resistance patterns
• Understanding use of isolation facilities and side rooms
• Scientific basis if the importance of aseptic technique in placing and managing
intravenous lines
• Understand of the impact of iatrogenic infection on mortality and morbidity
Attitude / Behaviour
ATTITUDE/ BEHAVIOURS
• Consider risk of infection before undertaking any procedure
• Participate in surveillance systems
• Make prevention of healthcare- associated infection a routine part of everyday
work
• Promote the principles of infection control and of limiting cross-infection
Competences and Skills
Core competences
• Principles and sources of cross infection
• Scrupulously minimizes the risk of transferring infection through personal
behavior
• Follow aseptic technique
• Uses personal protective equipment appropriately
• Follows disposal of “sharps” and any material that is an infection hazard
• Follows local guidelines/ protocols for antibiotic prescribing
• Posing risk through personal health problems
• Ensures that personal immunization are up-to-date
Most common mode of transmission of
pathogens is via hands!
 Infections acquired in healthcare
 Spread of antimicrobial resistance
So Why All the Fuss About Hand
Hygiene?
My Five
moments of
Hand Hygiene
My Five
moments of
Hand Hygiene
My Five
moments of
Hand Hygiene
My Five
moments of
Hand Hygiene
HCA Infections
• Resistance against most of the antibiotics
• No new antibiotics in pipeline
Evidence of Relationship
Between Hand Hygiene and
Healthcare-Associated
Infections
Substantial evidence that hand hygiene reduces
the incidence of infections
Historical study: Semmelweis
More recent studies: rates lower when
antiseptic handwashing was performed
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
Hand Hygiene Adherence in
Hospitals
1. Gould D, J Hosp Infect 1994;28:15-30. 2. Larson E, J Hosp Infect 1995;30:88-
106. 3. Slaughter S, Ann Intern Med 1996;3:360-365. 4. Watanakunakorn C,
Infect Control Hosp Epidemiol 1998;19:858-860. 5. Pittet D, Lancet
2000:356;1307-1312.
Year of Study Adherence Rate Hospital Area
1994 (1) 29% General and ICU
1995 (2) 41% General
1996 (3) 41% ICU
1998 (4) 30% General
2000 (5) 48% General
Self-Reported Factors
for Poor Adherence with
Hand Hygiene
 Handwashing agents cause irritation and dryness
 Sinks are inconveniently located/lack of sinks
 Lack of soap and paper towels
 Too busy/insufficient time
 Understaffing/overcrowding
 Patient needs take priority
 Low risk of acquiring infection from patients
Adapted from Pittet D, Infect Control Hosp Epidemiol 2000;21:381-386.
Hand Hygiene Definitions
• Handwashing
• Washing hands with plain soap and water
• Antiseptic handwash
• Washing hands with water and soap or other detergents
containing an antiseptic agent
• Alcohol-based handrub
• Rubbing hands with an alcohol-containing preparation
• Surgical hand hygiene/antisepsis
• Handwashing or using an alcohol-based handrub before
operations by surgical personnel
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
Indications for Hand
Hygiene
When hands are visibly dirty, contaminated,
or soiled, wash with non-antimicrobial or
antimicrobial soap and water.
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
Indications for Hand
Hygiene
When hands are visibly dirty, contaminated,
or soiled, wash with non-antimicrobial or
antimicrobial soap and water.
If hands are not visibly soiled, use an
alcohol-based hand rub for routinely
decontaminating hands.
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
Specific Indications for Hand
Hygiene
•Before:
• Patient contact
• Donning gloves when inserting a CVC
• Inserting urinary catheters, peripheral vascular catheters, or other invasive
devices that don’t require surgery
•After:
• Contact with a patient’s skin
• Contact with body fluids or excretions, non-intact skin, wound dressings
• Removing gloves
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
Efficacy of Hand Hygiene Preparations
in Killing Bacteria
Good Better Best
Plain Soap Antimicrobial
soap
Alcohol-based
handrub
Ability of Hand Hygiene
Agents to Reduce Bacteria on
Hands
Adapted from: Hosp Epidemiol Infect Control, 2nd
Edition, 1999.
0.0
1.0
2.0
3.0
0 60 180 minutes
0.0
90.0
99.0
99.9
log%
BacterialReduction
Alcohol-based handrub
(70% Isopropanol)
Antimicrobial soap
(4% Chlorhexidine)
Plain soap
Time After Disinfection
Baseline
Time Spent Cleansing Hands:
one nurse per 8 hour shift
Hand washing with soap and water: 56
minutes
• Based on seven (60 second) handwashing episodes per
hour
Alcohol-based handrub: 18 minutes
• Based on seven (20 second) handrub episodes per hour
Voss A and Widmer AF, Infect Control Hosp Epidemiol 1997:18;205-208.
Time Spent Cleansing
Hands:
one nurse per 8 hour shift
Hand washing with soap and water: 56
minutes
• Based on seven (60 second) handwashing episodes per
hour
Alcohol-based handrub: 18 minutes
• Based on seven (20 second) handrub episodes per hour
Voss A and Widmer AF, Infect Control Hosp Epidemiol 1997:18;205-208.
Time Spent Cleansing
Hands:
one nurse per 8 hour shift
Hand washing with soap and water: 56
minutes
• Based on seven (60 second) handwashing episodes per
hour
Alcohol-based handrub: 18 minutes
• Based on seven (20 second) handrub episodes per hour
Voss A and Widmer AF, Infect Control Hosp Epidemiol 1997:18;205-208.
~ Alcohol-based handrubs reduce time
needed for hand disinfection ~
Recommended Hand
Hygiene Technique
•Handrubs
• Apply to palm of one hand, rub hands together
covering all surfaces until dry
• Volume: based on manufacturer
•Handwashing
• Wet hands with water, apply soap, rub hands
together for at least 15 seconds
• Rinse and dry with disposable towel
• Use towel to turn off faucet
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
Gloving
•Wear gloves when contact with blood or other
potentially infectious materials is possible
•Remove gloves after caring for a patient
•Do not wear the same pair of gloves for the care
of more than one patient
•Do not wash gloves
•Change gloves when moving from a
contaminated to a clean body site
Guideline for Hand Hygiene are Settings. MMWR 2002; vol. 51, no.
RR-16.
Jewelry
•rings were substantial risk factor for
carriage of gram-negative bacilli and S.
aureus
• the concentration of organisms
recovered correlated with the number
of rings worn
Fingernails and Artificial
Nails
•Natural nail tips should be kept to ¼ inch in
length
•Artificial nails should not be worn when
having direct contact with high-risk patients
(e.g., ICU, OR)
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
Administrative Measures to Improve Hand
Hygiene
•Make improved hand hygiene an
institutional priority
•Place alcohol-based handrubs at entrance
to patient room, or at bedside
• Provide HCWs with pocket-sized containers
Guideline for Hand Hygiene in Health-care Settings. MMWR 2002;
vol. 51, no. RR-16.
Summary
Alcohol-Based Handrubs:
What benefits do they provide?
•Require less time
•More effective for standard handwashing than
soap
•More accessible than sinks
•Reduce bacterial counts on hands
•Improve skin condition
Hand hygiene pgr

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Hand hygiene pgr

  • 2.
  • 3. What are the next 28 minutes about ! Knowledge • Understand importance of Hand washing • Principle of appropriate antibiotics • Familiarity with local resistance patterns • Understanding use of isolation facilities and side rooms • Scientific basis if the importance of aseptic technique in placing and managing intravenous lines • Understand of the impact of iatrogenic infection on mortality and morbidity
  • 4. Attitude / Behaviour ATTITUDE/ BEHAVIOURS • Consider risk of infection before undertaking any procedure • Participate in surveillance systems • Make prevention of healthcare- associated infection a routine part of everyday work • Promote the principles of infection control and of limiting cross-infection
  • 5. Competences and Skills Core competences • Principles and sources of cross infection • Scrupulously minimizes the risk of transferring infection through personal behavior • Follow aseptic technique • Uses personal protective equipment appropriately • Follows disposal of “sharps” and any material that is an infection hazard • Follows local guidelines/ protocols for antibiotic prescribing • Posing risk through personal health problems • Ensures that personal immunization are up-to-date
  • 6.
  • 7. Most common mode of transmission of pathogens is via hands!  Infections acquired in healthcare  Spread of antimicrobial resistance So Why All the Fuss About Hand Hygiene?
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 17. HCA Infections • Resistance against most of the antibiotics • No new antibiotics in pipeline
  • 18. Evidence of Relationship Between Hand Hygiene and Healthcare-Associated Infections Substantial evidence that hand hygiene reduces the incidence of infections Historical study: Semmelweis More recent studies: rates lower when antiseptic handwashing was performed Guideline for Hand Hygiene in Health-care Settings. MMWR 2002; vol. 51, no. RR-16.
  • 19. Hand Hygiene Adherence in Hospitals 1. Gould D, J Hosp Infect 1994;28:15-30. 2. Larson E, J Hosp Infect 1995;30:88- 106. 3. Slaughter S, Ann Intern Med 1996;3:360-365. 4. Watanakunakorn C, Infect Control Hosp Epidemiol 1998;19:858-860. 5. Pittet D, Lancet 2000:356;1307-1312. Year of Study Adherence Rate Hospital Area 1994 (1) 29% General and ICU 1995 (2) 41% General 1996 (3) 41% ICU 1998 (4) 30% General 2000 (5) 48% General
  • 20. Self-Reported Factors for Poor Adherence with Hand Hygiene  Handwashing agents cause irritation and dryness  Sinks are inconveniently located/lack of sinks  Lack of soap and paper towels  Too busy/insufficient time  Understaffing/overcrowding  Patient needs take priority  Low risk of acquiring infection from patients Adapted from Pittet D, Infect Control Hosp Epidemiol 2000;21:381-386.
  • 21. Hand Hygiene Definitions • Handwashing • Washing hands with plain soap and water • Antiseptic handwash • Washing hands with water and soap or other detergents containing an antiseptic agent • Alcohol-based handrub • Rubbing hands with an alcohol-containing preparation • Surgical hand hygiene/antisepsis • Handwashing or using an alcohol-based handrub before operations by surgical personnel Guideline for Hand Hygiene in Health-care Settings. MMWR 2002; vol. 51, no. RR-16.
  • 22. Indications for Hand Hygiene When hands are visibly dirty, contaminated, or soiled, wash with non-antimicrobial or antimicrobial soap and water. Guideline for Hand Hygiene in Health-care Settings. MMWR 2002; vol. 51, no. RR-16.
  • 23. Indications for Hand Hygiene When hands are visibly dirty, contaminated, or soiled, wash with non-antimicrobial or antimicrobial soap and water. If hands are not visibly soiled, use an alcohol-based hand rub for routinely decontaminating hands. Guideline for Hand Hygiene in Health-care Settings. MMWR 2002; vol. 51, no. RR-16.
  • 24. Specific Indications for Hand Hygiene •Before: • Patient contact • Donning gloves when inserting a CVC • Inserting urinary catheters, peripheral vascular catheters, or other invasive devices that don’t require surgery •After: • Contact with a patient’s skin • Contact with body fluids or excretions, non-intact skin, wound dressings • Removing gloves Guideline for Hand Hygiene in Health-care Settings. MMWR 2002; vol. 51, no. RR-16.
  • 25. Efficacy of Hand Hygiene Preparations in Killing Bacteria Good Better Best Plain Soap Antimicrobial soap Alcohol-based handrub
  • 26. Ability of Hand Hygiene Agents to Reduce Bacteria on Hands Adapted from: Hosp Epidemiol Infect Control, 2nd Edition, 1999. 0.0 1.0 2.0 3.0 0 60 180 minutes 0.0 90.0 99.0 99.9 log% BacterialReduction Alcohol-based handrub (70% Isopropanol) Antimicrobial soap (4% Chlorhexidine) Plain soap Time After Disinfection Baseline
  • 27. Time Spent Cleansing Hands: one nurse per 8 hour shift Hand washing with soap and water: 56 minutes • Based on seven (60 second) handwashing episodes per hour Alcohol-based handrub: 18 minutes • Based on seven (20 second) handrub episodes per hour Voss A and Widmer AF, Infect Control Hosp Epidemiol 1997:18;205-208.
  • 28. Time Spent Cleansing Hands: one nurse per 8 hour shift Hand washing with soap and water: 56 minutes • Based on seven (60 second) handwashing episodes per hour Alcohol-based handrub: 18 minutes • Based on seven (20 second) handrub episodes per hour Voss A and Widmer AF, Infect Control Hosp Epidemiol 1997:18;205-208.
  • 29. Time Spent Cleansing Hands: one nurse per 8 hour shift Hand washing with soap and water: 56 minutes • Based on seven (60 second) handwashing episodes per hour Alcohol-based handrub: 18 minutes • Based on seven (20 second) handrub episodes per hour Voss A and Widmer AF, Infect Control Hosp Epidemiol 1997:18;205-208. ~ Alcohol-based handrubs reduce time needed for hand disinfection ~
  • 30. Recommended Hand Hygiene Technique •Handrubs • Apply to palm of one hand, rub hands together covering all surfaces until dry • Volume: based on manufacturer •Handwashing • Wet hands with water, apply soap, rub hands together for at least 15 seconds • Rinse and dry with disposable towel • Use towel to turn off faucet Guideline for Hand Hygiene in Health-care Settings. MMWR 2002; vol. 51, no. RR-16.
  • 31.
  • 32.
  • 33. Gloving •Wear gloves when contact with blood or other potentially infectious materials is possible •Remove gloves after caring for a patient •Do not wear the same pair of gloves for the care of more than one patient •Do not wash gloves •Change gloves when moving from a contaminated to a clean body site Guideline for Hand Hygiene are Settings. MMWR 2002; vol. 51, no. RR-16.
  • 34. Jewelry •rings were substantial risk factor for carriage of gram-negative bacilli and S. aureus • the concentration of organisms recovered correlated with the number of rings worn
  • 35. Fingernails and Artificial Nails •Natural nail tips should be kept to ¼ inch in length •Artificial nails should not be worn when having direct contact with high-risk patients (e.g., ICU, OR) Guideline for Hand Hygiene in Health-care Settings. MMWR 2002; vol. 51, no. RR-16.
  • 36. Administrative Measures to Improve Hand Hygiene •Make improved hand hygiene an institutional priority •Place alcohol-based handrubs at entrance to patient room, or at bedside • Provide HCWs with pocket-sized containers Guideline for Hand Hygiene in Health-care Settings. MMWR 2002; vol. 51, no. RR-16.
  • 37. Summary Alcohol-Based Handrubs: What benefits do they provide? •Require less time •More effective for standard handwashing than soap •More accessible than sinks •Reduce bacterial counts on hands •Improve skin condition

Editor's Notes

  1. Clean hands are the single most important factor in preventing the spread of pathogens and antibiotic resistance in healthcare settings. Hand hygiene reduces the incidence of healthcare associated infections. CDC estimates that each year nearly 2 million patients in the United States get an infection in hospitals, and about 90,000 of these patients die as a result of their infection. More widespread use of hand hygiene products that improve adherence to recommended hand hygiene practices will promote patient safety and prevent infections.
  2. There is substantial evidence that hand hygiene reduces the incidence of infections. Semmelweis demonstrated that the mortality rate among mothers who delivered in the First Obstetrics Clinic at the General Hospital of Vienna was significantly lower when hospital staff cleaned their hands with an antiseptic agent than when they washed their hands with plain soap and water. In more recent studies healthcare-associated infection rates were lower when antiseptic handwashing was performed by personnel and went down when adherence to recommended hand hygiene practices improved.
  3. In general, adherence of healthcare workers to recommended hand hygiene procedures has been poor. Studies shown here are representative of the overall adherence rates which averaged about 40%. Adherence rates do vary by occupation.
  4. Healthcare workers have reported several factors that may negatively impact their adherence with recommended practices including; handwashing agents cause irritation and dryness, sinks are inconveniently located, lack of soap and paper towels, not enough time, understaffing or overcrowding, and patient needs taking priority. Lack of knowledge of guidelines/protocols, forgetfulness, and disagreement with the recommendations were also self reported factors for poor adherence with hand hygiene. Perceived barriers to hand hygiene are linked to the institution and HCWs colleagues. Therefore, both institutional and small-group dynamics need to be considered when implementing a system change to secure and improve HCWs hand hygiene practice.
  5. Hand hygiene is a general term that applies to either handwashing, antiseptic handwash, alcohol-based handrub, or surgical hand hygiene/antisepsis. Handwashing refers to washing hands with plain soap and water. Handwashing with soap and water remains a sensible strategy for hand hygiene in non-healthcare settings and is recommended by CDC and other experts. Antiseptic handwash refers to washing hands with water and soap or other detergents containing an antiseptic agent. Alcohol-based handrub refers to the alcohol-containing preparation applied to the hands to reduce the number of viable microorganisms. Surgical hand hygiene/antisepsis refers to an antiseptic handwash or antiseptic handrub performed preoperatively by surgical personnel to eliminate transient and reduce resident hand flora. Antiseptic detergent preparations often have persistent antimicrobial activity.
  6. Healthcare workers should wash hands with soap and water when hands are visibly dirty, contaminated or soiled and use an alcohol-based handrub when hands are not visibly soiled to reduce bacterial counts.
  7. Healthcare workers should wash hands with soap and water when hands are visibly dirty, contaminated or soiled and use an alcohol-based handrub when hands are not visibly soiled to reduce bacterial counts.
  8. Hand hygiene is indicated before: patient contact, donning gloves when inserting a central venous catheter (CVC), and inserting urinary catheters, peripheral vascular catheters, or other invasive devices that don’t require surgery. Hand hygiene is also indicated after contact with a patient’s intact skin, contact with body fluids or excretions, non-intact skin, or wound dressings, and after removing gloves. Gloves should be used when a HCW has contact with blood or other body fluids in accordance with universal precautions.
  9. Plain soap is good at reducing bacterial counts but antimicrobial soap is better, and alcohol-based handrubs are the best.
  10. This graph shows that alcohol-based handrub is better than handwashing at killing bacteria. Shown across the top of this graph is the amount of time after disinfection with the hand hygiene agent. The left axis shows the percent reduction in bacterial counts. The three lines represent alcohol-based handrub, antimicrobial soap, and plain soap.
  11. The time required for nurses to leave a patient’s bedside, go to a sink, and wash and dry their hands before attending the next patient is a deterrent to frequent handwashing or hand antisepsis. More rapid access to hand hygiene materials could help improve adherence. Alcohol-based handrubs may be a better option than traditional handwashing with plain soap and water or antiseptic handwash because they require less time, act faster, and irritate hands less often.
  12. The time required for nurses to leave a patient’s bedside, go to a sink, and wash and dry their hands before attending the next patient is a deterrent to frequent handwashing or hand antisepsis. More rapid access to hand hygiene materials could help improve adherence. Alcohol-based handrubs may be a better option than traditional handwashing with plain soap and water or antiseptic handwash because they require less time, act faster, and irritate hands less often.
  13. The time required for nurses to leave a patient’s bedside, go to a sink, and wash and dry their hands before attending the next patient is a deterrent to frequent handwashing or hand antisepsis. More rapid access to hand hygiene materials could help improve adherence. Alcohol-based handrubs may be a better option than traditional handwashing with plain soap and water or antiseptic handwash because they require less time, act faster, and irritate hands less often.
  14. These recommendations will improve hand hygiene practices of HCWs and reduce transmission of pathogenic microorganisms to patients and personnel in healthcare settings. When decontaminating hands with an alcohol-based handrub, apply product to palm of one hand and rub hands together, covering all surfaces of hands and fingers, until hands are dry. When washing hands with soap and water, wet hands first with water, apply the amount of soap recommended by the manufacturer, and rub hands together for at least 15 seconds, covering all surfaces of the hands and fingers. Rinse hands with water, dry thoroughly with a disposable towel, and use the towel to turn off the faucet.
  15. Wearing gloves reduces the risk of healthcare workers acquiring infections from patients, prevents flora from being transmitted from healthcare workers to patients, and reduces contamination of the hands of healthcare workers by flora that can be transmitted from one patient to another. Gloves should be used when HCWs have contact with blood or other body fluids. Gloves should be removed after caring for a patient. The same pair of gloves should not be worn for the care of more than one patient. Gloves should not be washed or reused.
  16. Nail length is important because even after careful handwashing, HCWs often harbor substantial numbers of potential pathogens in the subungual spaces. Numerous studies have documented that subungual areas of the hand harbor high concentrations of bacteria, most frequently coagulase-negative staphylococci, gram-negative rods (including Pseudomonas spp.), corynebacteria, and yeasts. Natural nail tips should be kept to ¼ inch in length. A growing body of evidence suggests that wearing artificial nails may contribute to transmission of certain healthcare-associated pathogens. Healthcare workers who wear artificial nails are more likely to harbor gram-negative pathogens on their fingertips than are those who have natural nails, both before and after handwashing. Therefore, artificial nails should not be worn when having direct contact with high risk patients.
  17. Make improved hand hygiene an institutional priority and provide appropriate administrative support and financial resources. Several administrative measures may help improve hand hygiene adherence among personnel who work in areas where high workloads and high intensity of patient care are anticipated. These include placing alcohol-based handrubs at the entrance to patients’ rooms, or at the bedside and providing healthcare workers with individual pocket-sized containers.
  18. In summary, alcohol-based handrubs provide several advantages compared with handwashing with soap and water, because they not only require less time, they also act faster. In addition, alcohol-based handrubs are more effective for standard handwashing than soap, are more accessible than sinks, are the most efficacious agents for reducing the number of bacteria on the hands of healthcare workers, and can even provide improved skin condition.