This document discusses nosocomial (hospital-acquired) infections. It begins by outlining the chain of infection and explaining why isolation is important to control transmission. It then discusses the basics of infection control, including standard precautions like hand hygiene, personal protective equipment, waste disposal, and environmental cleaning. It notes that nosocomial infections increase hospital stays and costs. Common types are also outlined. Strategies to reduce transmission include proper hand hygiene, isolation, appropriate staffing, and decolonization efforts. The roles and responsibilities of healthcare workers and facilities in preventing the spread of infections are emphasized.