The document discusses protein and fiber needs for athletes. It recommends endurance athletes consume 1.2-1.4 g/kg protein daily and strength athletes consume 1.2-1.7 g/kg daily. While intakes up to 2.0 g/kg may support muscle growth, higher intakes are unlikely to provide benefits and could negatively impact hydration, nutrient quality, and health. The document also outlines different types of fiber, their physiological effects, health benefits including regularity and disease reduction, and recommends 25-38 g of fiber intake daily depending on gender.
Inborn errors of metabolism- focusing on its predominant adult onset forms, neurological perspective, clinical & biochemical approach to diagnosis, and neuroimaging findings.
Inborn errors of amino acid metabolismRamesh Gupta
Inherited disorders of amino acid metabolism e.g. phenylketonuria, maple syrup urine disease, alkaptonuria, homocystinuria, Hartnup disease etc for medical, biochemistry and biology undergraduates
Inborn errors of metabolism- focusing on its predominant adult onset forms, neurological perspective, clinical & biochemical approach to diagnosis, and neuroimaging findings.
Inborn errors of amino acid metabolismRamesh Gupta
Inherited disorders of amino acid metabolism e.g. phenylketonuria, maple syrup urine disease, alkaptonuria, homocystinuria, Hartnup disease etc for medical, biochemistry and biology undergraduates
At the end of this lecture, the students should be able to:-
1. Differentiate simple carbohydrates and complex carbohydrate
2. Describe the function of carbohydrates in the body
3. Demonstrate knowledge of health with carbohydrates
Dietary fiber or roughage is the indigestible portion of food derived from plants. It has two main components: Soluble fiber, which dissolves in water, is readily fermented in the colon into gases and physiologically active byproducts, and can be prebiotic and viscous.
This is a presentation by Dada Robert in a Your Skill Boost masterclass organised by the Excellence Foundation for South Sudan (EFSS) on Saturday, the 25th and Sunday, the 26th of May 2024.
He discussed the concept of quality improvement, emphasizing its applicability to various aspects of life, including personal, project, and program improvements. He defined quality as doing the right thing at the right time in the right way to achieve the best possible results and discussed the concept of the "gap" between what we know and what we do, and how this gap represents the areas we need to improve. He explained the scientific approach to quality improvement, which involves systematic performance analysis, testing and learning, and implementing change ideas. He also highlighted the importance of client focus and a team approach to quality improvement.
How to Create Map Views in the Odoo 17 ERPCeline George
The map views are useful for providing a geographical representation of data. They allow users to visualize and analyze the data in a more intuitive manner.
We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
1. Protein for Athletes
American College of Sports Medicine (ACSM) /
American Dietetic Association (ADA)
–Endurance athletes, 1.2 to 1.4 g/kg per day
• Accounts for greater use of protein as fuel for energy
–Strength athletes, 1.2 to 1.7 g/kg per day
• To support muscle growth, particularly during early training phase when gains
are greatest and protein utilization is less efficient
Clinical studies suggest there is no apparent
benefit at intakes above 2.0 g/kg per day
2. How much protein for athletes?
• Many athletes may already meet or exceed protein
recommendations
– Definition of “high protein” can be the absolute amount of
protein, % of total energy (calories), or protein ingested
per kg of body weight
• Strength athletes in particular may believe that much
higher protein intakes are needed for muscle building
– Intakes at 4- to 6-g/kg range are not uncommon
– Unlikely to provide benefit beyond 2.0 g/kg
– It is possible that this much protein intake could adversely
affect the nutrient quality of the overall diet
3. Risks of High Protein
Hydration status
– Nitrogen that is obtained from consuming protein must be excreted in the
urine as urea
– Increased urinary output due to high protein load may increase chances of
dehydration
Diets very high in protein may lack appropriate amounts
of carbohydrate, fiber, and some vitamins/minerals
– Could impair exercise performance
– Could increase long-term risk of diseases such as colon cancer
• Possibly due to lack of fiber or increased intake of red meat
Excessively fatty protein sources could increase risk
of cardiovascular disease
– Choose mostly lean protein sources
• For example, salmon is more desirable than a ribeye steak
4. Branched Chain Amino Acids
• Make up 40% of the daily requirements of essential amino
acids
5. Branched Chain Amino Acids
BCAAs are
Unlike other amino acids, most BCAA
metabolism occurs in skeletal muscle
– Liver lacks first 2 enzymes in the pathway that break
down BCAAs
Supplemental free form, bypass the liver and gut
and go directly into the blood stream.
BCAAs inhibit brains ability to uptake tryptophan
6. Leucine
– The bodies need for leucine is 25 times greater than
the available free amino acid pool.
– Stimulates protein synthesis by activating insulin
– Insulin increases a.a. uptake
– Incorporation of BCAAs in muscle is IGF-1 dependent
– IGF-1 stimulates muscle synthesis
– Chronic low levels of BCAAs will show up in urine
– β-hydroxy-β-methylbutyrate (HMB) is derived from the
breakdown of leucin
– Some evidence in humans that doses of 3 g/day may
be effective at preventing muscle breakdown
• Additive benefits with creatine
– Some studies suggest that HMB may provide greater
benefit to untrained people who start weight training
compared with previously conditioned athletes
7. Should athletes Supplement?
If protein requirements are met, the individual AA
requirements should be met as well
Estimated that 3-18% of workout energy is provided by
BCAAs
Leucine increases release of fats for energy
Claims mainly center on decreasing muscle soreness and
improving either performance or recovery from exercise
Doses can range from 2 to 7 g/day to more than 20 g/day
taken before during and after
There are potential risks associated with AA supplements
– Large doses of single AAs can prevent the absorption of other AAs, which may
lead to diarrhea
– Can indirectly cause deficiency of other AAs as a result
8. Phosphocreatine
• aka creatine phosphate (PCr)
• Rapidly mobilizable reserve
of high energy phosphate for
skeletal muscle (and brain)
• Formed from parts of Arg,
Gly & Met
• Can donate phosphate to
ADP anaerobically in the first
2-7 seconds following an
intense muscular effort
• Forward and reverse reaction
catalyzed by CK, which is a
marker of muscle damage
10. Alcohol Absorption
• Small amounts absorbed
in mouth and esophagus
• 20% absorbed directly
across stomach wall
• Food delays diffusion
• Most absorbed by simple
diffusion in the upper
small intestine
• Distributed wherever
water is found
11. Alcohol metabolism
1) Alcohol Dehydrogenase System
- women have less
- varies among ethnic groups
- NADH production turns of TCA cycle
- Excess acetyl CoA converted to FATTY ACIDS
- Fatty liver develops
12. 2) Microsomal Ethanol-oxidizing
System (MEOS)
• When ADH cannot keep up with demand
• Occurs in liver, in cytosol of cells
• Also used to metabolize drugs and foreign substances
• Reduces bodies ability to detoxify drugs overdose
• Increases alcohol metabolism, thus tolerance leads to weight
loss
13. 3) Catalase Metabolism of Alcohol
• Found in liver
• Minor pathway for alcohol metabolism
Ethanol Acetaldehyde
H2O2 H2O
Catalase
14. Alcohol Metabolism
• Depends on:
- Sex
- race
- size
- food
- physical condition
- alcohol content
• Amount of alcohol
dehydrogenase
• Alcohol cannot be
stored and has priority
in metabolism
15.
16. Negative effects on vitamins and
minerals
• Thiamin
• Niacin
• B6
• B12
• Folate
• Vitamin C
• Vitamin A
• Vitamin D
• Vitamin K
• Vitamin E
• Magnesium
• Zinc
• Iron
17. Alcoholics and malnutrition
• Poor diet
• Alcohol has energy but no nutrients
• Lack of interest in food: GI problems
• Alcohol interferes with absorption of amino
acids
• Alcohol races blood level of fats
18. Liver Damage
• Build up of
acetaldehyde
• Production of free
radicals
• Alcohol inhibits
body’s natural
antioxidant systems
• Advanced stages of
liver damage are
not reversible
19. Fetal Alcohol Syndrome
• Alcohol reaches fetus
• Deprives brain of
oxygen and nutrients
• About 4 drinks a day or
binge drinking while
pregnant
• Prenatal and postnatal
growth retardation
• Brain and CNS
impairment
• Abnormalities of face
and skull
• increased rate of birth
defects
20. Health Benefits of Alcohol
• Moderate drinking
associated with reduced
mortality
• ≤ 2 drinks for men, ≤ 1
drink for femal
• Reduced cardiovascular
disease
-reduces blood clotting
-increase HDL
-reduced inflammation
• Polyphenols
• Relaxation and
socialization
21. Fiber
• Plant cell wall contains > 95% of dietary fibers
- cellulose, hemicellulose, lignin, pectins
-Lignin structural support
-Pectin intercellular cement
-Cereal bran hemicellulose and lignin
-Fruit & Vegetables cellulose and pectin
• Starch energy storage is found within the
cells walls
23. Fiber
Dietary + Functional = Total Fiber
• Dietary – Found natuRally in foods
• Functional – forms added to foods
• Insoluble – Not fermented by bacteria
in the colon
• Soluble – Fermentable
25. Polysaccharides
1. Cellulose
• Polysaccharide of glucose
• Most abundant substance
in plant kingdom
• Β- 1,4 glycosidic linkages
• Water insoluble
• Does not provide energy
• Bran, legumes, nuts peas,
root vegetables, cabbage
• Cotton is pure cellulose
26. Insoluble fibers – Exterior/hulls &
Structural
2. Hemi-cellulose
• Mixture of
pentoses &
hexoses
• Linked to lignin
in cell wall
• Amorphous
• Partially soluble
in mild alkali
3. Lignin
• Highly branched
• Not digested by
colonic bacteria
• Non-CHO
• Structural support
• Roots vegetables,
carrots, wheat,
fruits with seeds
27. Soluble Fibers – inside & around plant
4. Pectin
• gel forming
• Amorphous
• Intracellular cement –
spaces b/w cell wall
• Almost completely
metabolized by colonic
bacteria
• Apples, strawberries &
citrus
• Added jellies & jams
5. Gums/Mucilages
• Secreted at the site of
plant injury: tree
exudates
• Highly branched
• Highly fermented by
colon bacteria
• Gum arabic is a food
additive for gelling
• Caramels, gumdrops,
toffee, bakery goods,
salad dressings, oatmeal
28. Physiological & Metabolic Effects
Effects of Fiber
1. Solubility in water
• delay gastric emptying
• Increase transit time
• Decrease nutrient absorption
2. Water-holding capacity
• Delay gastric emptying
• Reduced mixing of GI contents w/ digestive
enzymes
• Delayed nutrient absorption
• Shortened transit time
29. 3. Ability to bind (adsorption) molecules
• Decreased absorption of lipids
• Increased bile excretion
• Lower serum cholesterol
• Altered mineral balance
4. Fermentability by intestinal bacteria
• Microflora produces SCFAs
- energy
- cell proliferation
-increases water absorption in the colon
Physiological & Metabolic Effects
Effects of Fiber
31. Pre & Pro – biotic Diets
Medical Nutritional Therapy
• Pro-biotic
- ingestion of certain foods with live cultures containing
certain strains of bacteria to increase the counts of
specific microflora of the GI tract
-Yogurt
-survive digestion and then colonize lower GI tract
• Prebiotic
-food ingredients that are not digested or absorbed but
can stimulate the growth/activity of selected types of
bacteria in the colon
- Oligofructose or inulin (non-digestible oligosaccharides)
32. Health benefits of Dietary Fiber
• Promotes softer, larger stool and regularity
• Slows glucose absorption
• Increases satiety
• Reduces blood cholesterol
• Reduces heath disease
• Reduces hemorrhoids and diverticula
33. Nutrition and GI disorders
• Constipation
- reduced by fiber, fluid intake, exercise
• Diarrhea
• Diverticulosis
- Pouches along colon
- high fiber diet reduces formation
34. Recommended Dietary Fiber Intake
• Adequate intake (14g/1000 kcal):
- 25 g/day for women
- 38 g/day for men
- US intake: 13-17 g/day
• Too much fiber (>60 g/day)
- require extra intake of fluid
- binds to some minerals (Fe & Zn)
- fill the stomach of young child quickly
Editor's Notes
Acetaldehyde dehyrogenase
Short chain fatty acids
Energy mostly used by bacteria