Blood - heamatinics

1. SHUBHAM KUMAR VISHWAKARMA
5th sem B.Pharm

26. Haematuria-- presence of blood in urine

34. A hematinic is a nutrient required for the formation
of blood cells in the process of hematopoiesis. The
main hematinics are iron, B12, and folate. Deficiency
in hematinics can lead to anaemia. In cases of
hematinic deficiency, hematinics can be administered
as medicines, in order to increase
the hemoglobin content of the blood.
Erythropoietin (EPO) is a hormone that
stimulates erythropoiesis

35. How the interaction occurs
 Your medicine contains aluminum, calcium, iron, lanthanum,
magnesium, and/or zinc, which are cations that may bind to
your antibiotic in your digestive tract. This prevents your body
from absorbing the antibiotic.
What might happen:
The blood levels of your antibiotic may be decreased, which will
decrease the effectiveness in treating your infection.
 Allergi
 Liver disfunction

36. • Amoxicilline & clavulenic acid 3 g ( beeta
lactmase inhibitor) antibiotic
• Use in bacterial infection
• Eg UIT, wound healing

38. • Mean corpuscular
volume (MCV)
laboratory test
• completeblood count
(CBC)
• mean corpuscular
hemoglobin
concentration
(MCHC) test

39. • Stomach & intestinal problem eg ulcer, colitis
• Tetracycline antibiotics
• Thyroid medication (levo thyroxine)
• Antibiotics – ciprofloxacine , quinolones , levofloxacine
• Iron Metabolism Disorder causing Increased Iron Storage
• Ulcerated Colon

40. Iron salts are often available in combinations
with "absorption stimulating" additives (e.g.
ascorbic acid) and as gastric juice-resistant
and slow-release preparations. These special
preparations probably do not offer any
relevant advantage compared to mono-
preparations.

41. • Penicillamine interacts with IRON
Penicillamine is used for Wilson's disease and
rheumatoid arthritis. Iron might decrease how
much penicillamine your body absorbs and
decrease the effectiveness of penicillamine. To
avoid this interaction take iron two hours before
or two hours after taking penicillamine.

42. Side Effects
Constipation, diarrhea, stomach cramps,
or upset stomach may occur. These effects are
usually temporary and may disappear as your
body adjusts to this medication
Iron may cause your stools to turn black, an
effect that is not harmful.

70. Hematinics classification
Oral preparations
Ferrous gluconate
Ferrous sulphate
Ferrous fumarate
Colloidal ferric hydroxide
Carbonyl iron sulphate
Ferrous succinate
Ferrous glycine
Ferric glycerophosphate
Ferrous ammonium citrate
Ferrous aminoate
Ferric hydroxide polymaltose

71. Parenteral
Iron dextran
lron sorbitol citrate complex
Iron sucrose
Iron dextrin (polymaltose)
Vitamin B12
Cyanocobalamin
Methylcobalamin
Hydroxycobalamin

72. • Hematopoietic Growth Factors
•
Erythropoietin
• Darbepoietin

77. Sources