This document contains 30 multiple choice questions testing knowledge of endocrine physiology. The questions cover topics like the classes of hormones secreted by different endocrine glands (thyroid, pituitary, adrenal), their actions, regulation and effects on metabolism. Key glands and hormones discussed include the thyroid, parathyroid, adrenals, pancreas and their roles in calcium homeostasis, glucocorticoid and mineralocorticoid production, and insulin/glucagon regulation of blood sugar levels.

1. Endocrine Physiology MCQs :
1) Thyroid hormones belong to which class of hormone?
a) steroids
b) proteins
c) polypeptides
d) amino acid derivatives
2) Which is not found in biological membrane?
a) G-proteins
b) steroid receptors
c) lipids
d) proteins
3) Which of the following hormones does not need a second messenger?
a) FSH
b) LH
c) glucagon
d) oestrogen
4) The following hormones increase the level of intracellular cAMP except :
a) vasopressin
b) glucagon
c) parathyroid hormone
d) 1,25 DHCC

2. 5) Which of the following hormones is not secreted by the adenohypophysis?
a) ADH
b) ACTH
c) TSH
d) FSH
6) All of the following are stimuli for growth hormone release except :
a) hypoglycemia
b) stress
c) obesity
d) exercise
7) Somatomedins are synthesized in the following except :
a) liver
b) kidney
c) muscle
d) lungs
8) Site of action of ADH is :
a) Proximal tubule
b) Loop of Henle
c) Vasa Recta
d) Collecting tubule

3. 9) Oxytocin secretion promotes all of the following actions except :
a) myometrium contraction
b) lactogenesis
c) milk ejection
d) myoepithelial cell contraction of mammary glands
10) C-cells are present in :
a) thyroid gland
b) adrenal cortex
c) parathyroid gland
d) pituitary gland
11) Thyroid gland secretes approximately ___% T4 and ___%T3 :
a) 20,80
b) 10,90
c) 80,20
d) 90,10
12) Not an action of thyroid hormone :
a) raises BMR
b) increases cardiac output
c) decreases cholesterol
d) loss of libido

4. 13) Yellowish tint of skin in myxoedema is due to :
a) anaemia
b) increased bilirubin level
c) decreased cholesterol
d) carotenemia
14) A patient with hypothyroidism is likely to have :
a) subnormal body temperature
b) lid retraction
c) exophthalmos
d) moist hands and feet
15) The normal serum calcium level is ___mg/100 ml
a) 4-6
b) 6-8
c) 9-11
d) 14-16
16) Normal daily calcium excretion in urine is ___mg :
a) 50
b) 100
c) 200
d) 300

5. 17) For calcium metabolism, all of the following are required except :
a) vitamin D
b) parathyroid hormone
c) calcitonin
d) thyroxine
18) cholecalciferol is :
a) vitamin D3
b) precursor of vitamin D3
c) occurs in skin
d) physiologically active
19) The active form of vitamin D is :
a) calcium
b) 1,25 DHCC
c) parathyroid hormone
d) cholecalciferol
20) The primary site of 1,25 DHCC formation from its immediate precursor is :
a) bone
b) liver
c) kidney
d) skin

6. 21) Calcitonin is responsible for :
a) Increasing the plasma calcium level
b) decreasing the plasma calcium level
c) increasing parathyroid hormone level
d) decreasing thyroxine level
22) Tetany features include all except:
a) neuromuscular hyperexcitability
b) carpopedal spasm
c) trosseau’s sign
d) clotting defects
23) Renal calculi is seen in :
a) hyperthyroidism
b) hyperparathyroidism
c) cushing’s disease
d) addison’s disease
24) All are seen in Cushing’s syndrome except :
a) truncal obesity
b) hypertension
c) hypoglycemia
d) hirsutism

7. 25) The secretion of aldosterone is caused by :
a) angiotensin II
b) ACTH
c) epinephrine
d) insulin
26) Aldosterone secretion is regulated by the following except :
a) ACTH
b) calcium
c) blood volume
d) potassium
27) In addison’s disease, the following is seen :
a) hyperkalemia
b) increase in ECF volume
c) hyperglycemia
d) high blood pressure
28) Half life of insulin in plasma is :
a) 1 minute
b) 5-10 minutes
c) 20-30 minutes
d) 40-60 minutes

8. 29) Insulin acts at all the sites except :
a) liver
b) brain
c) adipose tissue
d) muscles
30) Which is false regarding Insulin ?
a) secreted by beta cells of pancreas
b) promotes gluconeogenesis
c) causes lipogenesis
d) promotes glycogenesis