The document describes the rules and questions from various rounds of a history of endocrinology quiz competition for a batch of students. It provides details of the scoring system and time limits for different types of questions in rounds like history, functional anatomy, buzzer, MCQ, recent advances, case scenarios, rush/relax and jumbled words. The rounds test the students' knowledge of topics like key figures, discoveries and concepts in the history of endocrinology as well as current advances through different question formats.

1. TKMC

2. Proudly presents………..

3. ‘13 BATCH

4. HISTORY ROUND
RULES
 Each Question Carries 10 Marks.
 Each Team Will Be Given 1 Minute For Each
Question In Sub Round 1 And 30 Seconds In
Sub Round 2.
 30 + 30 Seconds To Identify The Picture And
Answer The Question.
 Question Passes To The Next Team If
Unanswered.
 Such Answered Question Carries Half The
Mark Allotted.
 Question Cannot Be Passed In Sub Round 2 .

5. HISTORY ROUND
 Identify the person

6. HISTORY ROUND
 Identify the person
 what is his contribution
on endocrinology?

7. HISTORY ROUND
 Fredrick Grant Banting
 Isolation & use of
insulin for the control of
carbohydrate
metabolism.

8. HISTORY ROUND
 Who is this
personality?

9. HISTORY ROUND
 Who is this
personality?
 What is his role on
endocrinology?

10. HISTORY ROUND
 THOMAS ADDISION
 He has given the
details of
adrenocortical
deficiencies

11. HISTORY ROUND
 Identify the person.

12. HISTORY ROUND
 Identify the person.
 What is Cushing’s
disease?

13. HISTORY ROUND
 HARVEY WILLIAM
CUSHING
 Excessive cortisol
secretion due to
increased pituitary
activity

14. HISTORY ROUND
 Who worked on C Amp ?

15.  EARL SUTHERLAND

16. HISTORY ROUND
 Who introduced radio immunoassay for
the measurement of hormones ?

17.  BERSON & YALOW

18. HISTORY ROUND
 Who described about corticotropin
releasing factor ?

19. HISTORY ROUND
 SUFFRAN & SCHALLY

20. HISTORY ROUND
 Identify the person.
 What is his work in
endocrinology?

21. HISTORY ROUND
 WILLIAM MADDOCK BAYLISS
 He demonstrated hormonal regulation of
pancreatic secretion.

22. FUNCTIONAL ANATOMY
Rules
 Each question carries 5+5 = 10 marks.
 20 + 20 seconds for identification and
answering the related question.
 Should answer the first question to unlock
the 2nd question
 No pass allowed.

23. FUNCTIONAL ANATOMY
 Identify the picture.

24. FUNCTIONAL ANATOMY
 Identify The Picture.
 Why The Cells In The
Marked Zone Appear
Clear And
Homogenous .

25. FUNCTIONAL ANATOMY
Ans:
a. Histology of adrenal
gland
b. Because of
cholesterol
accumulation

26. FUNCTIONAL ANATOMY
a. Identify the picture.

27. FUNCTIONAL ANATOMY
a. Identify the picture.
b. Name the cells
present in the outer
zone

28. FUNCTIONAL ANATOMY
Ans:
a. Structure of islet of
langer hans
b. Alpha cells

29. FUNCTIONAL ANATOMY
a. Identify the picture.

30. FUNCTIONAL ANATOMY
a. Identify the picture.
b. Which is the
predominant cell

31. FUNCTIONAL ANATOMY
a. IDENTIFY THE
PICTURE.
b. WHICH IS THE
PREDOMINANT
CELL and WHAT IT
SECRETES.

32. FUNCTIONAL ANATOMY
Ans:
a. Histology of
parathyroid gland
b. Chief cells
,Parathormone

33. FUNCTIONAL ANATOMY
a. Identify the diagram.

34. FUNCTIONAL ANATOMY
a. Identify the diagram.
b. Who studied on
goitre about thyroid
dysfunction?

35. FUNCTIONAL ANATOMY
Ans:
a. Histology of thyroid
gland
b. Emil theodor kocher

36. FUNCTIONAL ANATOMY
 Name the special type of supporting cells
of pituitary gland ?

37. FUNCTIONAL ANATOMY
 Ans :- PITUICYTES

38. FUNCTIONAL ANATOMY
 Adrenal medulla is derived from ?

39. FUNCTIONAL ANATOMY
 Ans :- NEUROECTODERM

40. FUNCTIONAL ANATOMY
 What is epiphysis cerebri ?

41. FUNCTIONAL ANATOMY
 Ans :- PINEAL GLAND

42. BUZZER ROUND
Rules
 Each question carries 10 marks
 First team to press the buzzer will be
allowed to answer the question.
 If the allowed team gives wrong answer
five marks will be reduced from their
score.
 No pass allowed

43. BUZZER ROUND
 What is acromicria?

44. BUZZER ROUND
 What is Acromicria?
 Growth horomone deficieny in adults
leads to atrophy of the extremities

45. BUZZER ROUND
 SIMMONDS DISEASE ?

46. BUZZER ROUND
 SIMMONDS DISEASE ?
Ans: PANHYPOPITUITARISM

47. BUZZER ROUND
 What is medical adrenalectomy ?

48. BUZZER ROUND
 What is medical adrenalectomy ?
Ans:
inhibition of cortisol synthesis by
administration of high dose of
ketakonazole of metyrapone

49. BUZZER ROUND
EXPLANATION OF IRM ASSAY IS
____________

50. BUZZER ROUND
EXPLANATION OF IRM ASSAY IS
____________
ANS: IMMUNO RADIOMETRIC ASSAY

51. BUZZER ROUND
 WHICH IS AN INDEX OF BONE
RESORPTION

52. BUZZER ROUND
 HYDROXYPROLINURIA

53. BUZZER ROUND
 WHAT IS INCRETINS ?

54. BUZZER ROUND
 What is incretins ?
 Ans: gut hormones which stimulate insulin
secretion eg. Gip & glp -1

55. MCQ ROUND
Rules
 Each question carries 5 marks.
 Time allotted will be 1 minute
 Passing not allowed.

56. MCQ ROUND
1. Insulin increases the entry of glucose into
A. Reneal tubular cells
B. The mucosa of the smal intestine
C. Most neurons in the cerebral cortex
D. Skeletal muscle

57. MCQ ROUND
1. Insulin increases the entry of glucose into
A. Reneal tubular cells
B. The mucosa of the smal intestine
C. Most neurons in the cerebral cortex
D. Skeletal muscle

58. MCQ ROUND
2. Which of the following are incorrectly
paired?
A. Free fatty acid mobilization :
dehydroepiandrosterone
B. Muscle glycogenolysis : epinephrine
C. Kaliuresis : aldosterone
D. Hepatic glycogenesis : insulin

59. MCQ ROUND
2. Which of the following are incorrectly
paired?
A. Free fatty acid mobilization :
dehydroepiandrosterone
B. Muscle glycogenolysis : epinephrine
C. Kaliuresis : aldosterone
D. Hepatic glycogenesis :insulin

60. MCQ ROUND
3. Which of the following hormones has the
shortest plasma half life?
A. Corticosterone
B. Dehydroepiandrostrone
C. Aldosterone
D. Norepinephrine

61. MCQ ROUND
3. Which of the following hormones has the
shortest plasma half life?
A. Corticosterone
B. Dehydroepiandrostrone
C. Aldosterone
D. Norepinephrine

62. MCQ ROUND
4. Which of the following is not involved in
regulating plasma ca2+ levels?
A. Kidneys
B. Skin
C. Liver
D. Lungs

63. MCQ ROUND
4. Which of the following is not involved in
regulating plasma ca2+ levels?
A. Kidneys
B. Skin
C. Liver
D. Lungs

64. MCQ ROUND
5. Which of the following is not characteristic
of hypopituitarism?
A. Cachexia
B. Infertility
C. Low basal metabolic rate
D. Intolerance to stress

65. MCQ ROUND
5 which of the following is not characteristic
of hypopituitarism?
A. Cachexia
B. Infertility
C. Low basal metabolic rate
D. Intolerance to stress

66. MCQ ROUND
6. 17-ketosteroids are all except
A. Androsterone
B. Ehocholanolone
C. Dhea-s
D. Corticosterone

67. MCQ ROUND
6. 17-ketosteroids are all except
A. Androsterone
B. Ehocholanolone
C. Dhea-s
D. Corticosterone

68. RECENT ADVANCES
Rules
 Question carries 10 marks.
 Time alloted will be 20 seconds
 Passing allowed
 If passed time will be reduced to 10
seconds.
 Marks for the each passed question will
be 5

69. RECENT ADVANCES
DEIODINASES CONTAINS _______
TRACE ELEMENT

70. RECENT ADVANCES
DEIODINASES CONTAINS _______
TRACE ELEMENT
ANS: SELENIUM

71. RECENT ADVANCES
LEPTIN RECEPTOR IS LINKED TO ____
ENZYME ACTIVITY

72. RECENT ADVANCES
LEPTIN RECEPTOR IS LINKED TO ____
ENZYME ACTIVITY
ANS: TYROSINE KINASE

73. RECENT ADVANCES
PROLACTIN ACTIVATE _______
SIGNALLING PATHWAY

74. RECENT ADVANCES
PROLACTIN ACTIVATE _______
SIGNALLING PATHWAY
ANS: JAK / STAT PATHWAY

75. RECENT ADVANCES
POINT MUTATIONS IN INSULIN GENE
CAN BE DEFECTED BY _____
TECHNIQUE.

76. RECENT ADVANCES
POINT MUTATIONS IN INSULIN GENE
CAN BE DEFECTED BY _____
TECHNIQUE.
ANS: OLIGUNUCLEOTIDE PROBE
HYBRIDIZATION

77. RECENT ADVANCES
RADIO RECEPTOR ASSAY IS MAINLY
USEFUL IN MEASURING THE ACTIVITY
OF ____ HORMONE

78. RECENT ADVANCES
RADIO RECEPTOR ASSAY IS MAINLY
USEFUL IN MEASURING THE ACTIVITY
OF ____ HORMONE
ANS: 1-25- DIHYDROXY
CHOLECALCIFEROL

79. RECENT ADVANCES
 PROHORMONE TO HORMONE
CONVERSION TAKES PLACE IN WHICH
INTRACELLULAR ORGANELLE?

80. RECENT ADVANCES
 PROHORMONE TO HORMONE
CONVERSION TAKES PLACE IN WHICH
INTRACELLULAR ORGANELLE?
 ANS: GOLGI APPARATUS

81. CASE SCENARIO
Rules
 Each question carries 5 + 5 = 10 marks
 Time alloted will be 90 seconds.
 No passing allowed.

82. CASE SCENARIO
 Identify the condition

83. CASE SCENARIO
a. Identify the condition
and the disease
causing this
b. Reason behind this

84. CASE SCENARIO
Ans
a. Hyperpigmentation due
to addisson’s
disease
b. Acth (msh) causes
hyper pigmentation

85. CASE SCENARIO
 Identify the condition

86. CASE SCENARIO
 Identify the marked
lesion
 What will be the
visual deffect
produced.

87. CASE SCENARIO
Ans:
 PITUITARY
ADENOMA.
 Bitemporal
hemianopia

88. CASE SCENARIO
a. Identify the picture

89. CASE SCENARIO
a. Identify the picture
b. What is the O2
consumption in
hypothyroidism ?

90. CASE SCENARIO
Ans:
a. Multinodular goitre
b. 150ml/dl

91. CASE SCENARIO
a. Identify the sign and
condition causing
this

92. CASE SCENARIO
a. Identify the sign and
condition causing this
b. Lethal level of calcium and
mention about calcium
regulatory proteins

93. CASE SCENARIO
Ans:
a. Trousseau’s sign
hypocalcemic tetany
b. 4mg/dl ,
CALMODULIN AND
CALBINDIN

94. CASE SCENARIO
 An eight year old child has pot belly,
delayed milestones and delayed eruption
of teeth .
 1 identify the condition
 2 what is the cause of the pot belly

95. Ans
 Cretinism
 Hypotonia of anterior abdominal wall
muscles

96. CASE SCENARIO
 A male patient aged 40 years, complaint
of extreme weakness despite voracious
eating , had polyuria and polydipsia. ON
INVESTIGATION HIS BLOOD GLUCOSE
FOUND TO BE 220mg/dl.
1. Glycosylated hb determine the blood
glucose level over a period of ?
2. What is the cause for polyuria?

97.  Ans
 1) 6-8wks
 2) osmotic diuresis

98. RUSH OR RELAX ROUND
Rules
 Team will be given the choice to opt rush /
relax question.
 Marks for rush question is 20 marks in 10
seconds
 For incorrect rush answer 5 marks will be
reduced from their score.
 Marks for relax question is 10 marks in 45
seconds
 No negative for relax question.

99. RUSH
 Plasma insulin level rise more rapidly by
ural glucose than iv glucose – true or
false

100. RUSH
 Plasma insulin level rise more rapidly by
ural glucose than iv glucose –
Ans: true

101. RELAX
 I am stimulated by low serum calcium, i
act through osteoblast and i bring down
phosphorus iam metabolised by kupfer
cells
Who am i ?

102. RUSH
 Of all the three layers of adrenal cortex
which is not influenced by ACTH

103. RUSH
 Of all the three layers of adrenal cortex
which is not influenced by ACTH
Ans :zona glomerulosa

104. RELAX
 Sweating
 Tachycardia
 Headache
 Hypertension
 Hyperglycemia
 Asthma
 ↑ Urinary vma
Who am i?

105. RUSH
 Prostaglandis was discovered by von-
euler in secretion of which gland

106. RUSH
 Prostaglandis was discovered by von-
euler in secretion of which gland
Ans : prostate gland

107. RELAX
 Calogenic effect of thyroid hormones is
by inducing which enzyme
 Diabetic keto acidosis is a state of
intracellular dehydration true or false

108. RUSH OR RELAX ROUND
 Na+/K+ atpase INCREASED O2
CONSUMPTION
 True

109. RUSH OR RELAX ROUND
 Diabetic keto acidosis is a state of
intracellular dehydration
Ans: true

110. JUMBLED WORDS
RULES
 EACH QUESTION CARRIES 10 + 10 = 20 MARKS.
 THE GIVEN WORD WILL BE A JUMBLED MEDICAL
TERMINOLOGY.
 EACH TEAM WILL BE GIVEN 10 MARKS TO
REARRANGE AND FIND THE WORD IN 30
SECONDS.
 THE CLUE WILL BE GIVEN AT YOUR REQUEST OR
BY THE END OF THE 30 SCONDS FOR WHICH 5
MARKS WILL BE REDUCED.
 TWO QUESTIONS RELATED TO THE MEDICAL
TERM WILL BE ASKED (5+5=10)

111. EXAMPLE
PEST SOSO ORID
OSTEOPOROSIS

112. JUMBLED WORDS
GEM CAL YARO

113. JUMBLED WORDS
Hint:
PITUITARY GLAND
DISORDER

114. ACROMEGALY

115. JUMBLED WORDS
 What happens to carbohydrate
metabolism in this condition
 What happens to internal organs

116. JUMBLED WORDS
Ans:
 Impaired glucose tolerance leading to
diabetes mellitus
 Organomegaly

117. JUMBLED WORDS
HYT DROITS
MOR

118. JUMBLED WORDS
Hint:
MEDICAL EMERGENCY
OF THYROID GLAND

119. JUMBLED WORDS
THYROID STROM

120. JUMBLED WORDS
 What symptoms does this condition
presents with?
 What are the percipitating events ?

121. JUMBLED WORDS
 Fever, tachycardia, circulatory collapse,
restlessness
 Major trauma such as surgery or illness in
a hyper thyroid patient

122. JUMBLED WORDS
ROMED SONNY
CNS

123. JUMBLED WORDS
Hint:
“This condition results in sodium and
water retention”

124. JUMBLED WORDS
CONN’S SYNDROME

125. JUMBLED WORDS
 Cause for this condition?
 What happens to ph in this condition?

126. JUMBLED WORDS
 TUMOR OR HYPERPLASIA OF ZONA
GLOMERULOSA (PRIMARY HYPER
ALDOSTERONISM)
 METABOLIC ALKALOSIS (Ph INCREASES)

127. RAPID FIRE ROUND
Rules
 Ten questions for each team.
 Time alloted will be 90 seconds.
 Each question carries 5 marks.
 No negative marks
 If answer is not known you can pass on to
next question.

129. RAPID FIRE ROUND
1. ACTH SECRETION IS MAX DURING
2. RECEPTORS FOR CALCITONIN IN BONE IS FOUND IN WHICH CELLS
3. SIADH IS ALSO CALLED AS
4. MAX NO. OF ISLETS OF LANGERHANS ARE SEEN IN
5. FIRST PROTIEN DETECTED TO POSSESS HORMONAL ACTIVITY
6. MOST IMPORTANT STIMULUS FOR SECRETION OF
ERYTHROPROTIEN SECRETION IS
7. MAJOR CATHECHOLAMINE FROM ADRENAL MEDULLA ?
8. NAME THE HORMONE RESPONSIBLE FOR SYMPTOMS OF
HYPOGLYCEMIA
9. BASAL METABOLIC RATE IS MAINLY REGULATED BY WHICH
HORMONE
10. 90% PLASMA CORTISOL IS BOUND TO

130. RAPID FIRE ROUND
1. ACTH SECRETION IS MAX DURING EARLY MORNING 6-8
2. RECEPTORS FOR CALCITONIN IN BONE IS FOUND IN WHICH CELLS
OSTEOCLAST
3. SIADH IS ALSO CALLED AS DILUTION SYNDROME
4. MAX NO. OF ISLETS OF LANGERHANS ARE SEEN IN TAIL OF
PANCREAS
5. FIRST PROTIEN DETECTED TO POSSESS HORMONAL ACTIVITY
INSULIN
6. MOST IMPORTANT STIMULANT FOR ERYTHROPROTIEN SECRETION
IS HYPOXIA
7. MAJOR CATHECHOLAMINE FROM ADRENAL MEDULLA ? ADRENALIN
8. NAME THE HORMONE RESPONSIBLE FOR SYMPTOMS OF
HYPOGLYCEMIA NOREPINEPHRINE
9. BASAL METABOLIC RATE IS MAINLY REGULATED BY WHICH
HORMONE THYROXINE
10. 90% PLASMA CORTISOL IS BOUND TO TRANSCORTIN

132. RAPID FIRE ROUND
1. GLUT – 6 ?
2. MAJOR ADRENAL SEX STEROIDS ARE
3. SOMATOSTATIN IS DERIVED FROM WHICH CELLS
4. ENDOGENOUS INSULIN PRODUCTION IS MEASURED BY
5. DAILY DIETRY REQUIREMENT OF CALCIUM IN A PREGNANT
WOMEN/DAY IS
6. DIABETIC KETOACIDOSIS IS A STATE OF INTRA-CELLULAR
DEHYDRATION TRUE OR FALSE
7. GROWTH HORMONE IS SYNTHESISED BY
8. ABSENCE OF GH RECEPTORS RESULTS IN WHICH CONDITION
9. HERRING’S BODIES ARE SEEN IN
10. MELATONIN SECRETION IS MAX DURING ?

133. RAPID FIRE ROUND
1. GLUT – 6 ? PSUEDOGENE
2. MAJOR ADRENAL SEX STEROIDS ARE (DHEA) ANDROSTENEDIONE
3. SOMETO STATIN IS DERIVED FROM WHICH CELLS DELTA CELL
4. ENDOGENOUS INSULIN PRODUCTION IS MEASURED BY C-PEPTIDE
5. DAILY DIETRY REQUIREMENT OF CALCIUM IN A PREGNANT
WOMEN/DAY IS 1500mg/day
6. DIABETIC KETOACIDOSIS IS A STATE OF INTRA-CELLULAR
DEHYDRATION TRUE OR FALSE
7. GROWTH HORMONE IS SYNTHESISED BY ARCUATE NUCLEUS
8. ABSENCE OF GH RECEPTORS RESULTS IN WHICH CONDITION
AFRICAN PYGMIES PWART
9. HERRING’S BODIES ARE SEEN IN POSTERIOR PITUITARY
10. MELATONIN SECRETION IS MAX DURING ? 11AM TO 7PM

136. RAPID FIRE ROUND
1. Physiological secretion of insulin stops at what level of
plasma glucose ?
2. Name the only hypoglycemic hormone?
3. What is pendrin ?
4. Renal threshold of blood glucose is
5. Precussor aminoacid for melatonin ?
6. Hyper secretion of thymin results in
7. Thromboxene a2 is systhesised by
8. Urinary vanillyl mandelic acid is elevated in which
condition
9. Acidophillic cells or pituitary gland secrets
10. Somotomedin c10 also known as

137. RAPID FIRE ROUND
1. Physiological secretion of insulin stops at what level of
plasma glucose ? 90mg/dl
2. Name the only hypoglycemic hormone? Insulin
3. What is pendrin ? cl -/ i – exchanger
4. RENAL THRESHOLD OF BLOOD GLUCOSE IS
180mg/dl
5. Precussor aminoacid for melatonin tryptophan
6. Hyper secretion of thymin results in myathenia gravis
7. Thromboxene a2 is systhesised by platelets
8. Urinary vanillyl mandilic acid is elevated in which
condition phechromocytoma
9. Acidophillic cells or pituitary gland secrets gh/prolactin
10. Somotomedin c10 also known as igf-1